Detalhe da pesquisa
1.
Immune profiling of patients with extranodal natural killer/T cell lymphoma treated with daratumumab.
Ann Hematol
; 103(6): 1989-2001, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38233570
2.
A T-cell-redirecting bispecific G-protein-coupled receptor class 5 member D x CD3 antibody to treat multiple myeloma.
Blood
; 135(15): 1232-1243, 2020 04 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32040549
3.
Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice.
J Immunol
; 202(6): 1885-1894, 2019 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30710044
4.
A carboxylic acid isostere screen of the DHODH inhibitor Brequinar.
Bioorg Med Chem Lett
; 30(22): 127589, 2020 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33007394
5.
Discovery and optimization of a series of small-molecule allosteric inhibitors of MALT1 protease.
Bioorg Med Chem Lett
; 29(23): 126743, 2019 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31678006
6.
[2.2.1]-Bicyclic sultams as potent androgen receptor antagonists.
Bioorg Med Chem Lett
; 26(23): 5707-5711, 2016 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27836399
7.
Discovery of Alternative Binding Poses through Fragment-Based Identification of DHODH Inhibitors.
ACS Med Chem Lett
; 15(3): 381-387, 2024 Mar 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38505861
8.
Macrocyclic Carbon-Linked Pyrazoles As Novel Inhibitors of MCL-1.
ACS Med Chem Lett
; 14(7): 955-961, 2023 Jul 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37465311
9.
Modulation of cofilin phosphorylation by inhibition of the Lim family kinases.
Bioorg Med Chem Lett
; 22(18): 5995-8, 2012 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22902653
10.
N-Heterocyclic 3-Pyridyl Carboxamide Inhibitors of DHODH for the Treatment of Acute Myelogenous Leukemia.
J Med Chem
; 65(16): 11241-11256, 2022 08 25.
Artigo
Inglês
| MEDLINE | ID: mdl-35925768
11.
Drug safety is a barrier to the discovery and development of new androgen receptor antagonists.
Prostate
; 71(5): 480-8, 2011 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-20878947
12.
Discovery of Highly Potent and Selective IRAK1 Degraders to Probe Scaffolding Functions of IRAK1 in ABC DLBCL.
J Med Chem
; 64(15): 10878-10889, 2021 08 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34279092
13.
Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail.
Mol Cell Biol
; 27(8): 3165-75, 2007 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-17296734
14.
Design and synthesis of 4-[3,5-dioxo-11-oxa-4,9-diazatricyclo[5.3.1.0(2,6)]undec-4-yl]-2-trifluoromethyl-benzonitriles as androgen receptor antagonists.
Bioorg Med Chem Lett
; 20(15): 4491-5, 2010 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20584610
15.
SAR of PXR transactivation in benzimidazole-based IGF-1R kinase inhibitors.
Bioorg Med Chem Lett
; 20(5): 1744-8, 2010 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20153189
16.
Castration-resistant prostate cancer: locking up the molecular escape routes.
Clin Cancer Res
; 15(10): 3251-5, 2009 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19447877
17.
BMS-536924 reverses IGF-IR-induced transformation of mammary epithelial cells and causes growth inhibition and polarization of MCF7 cells.
Clin Cancer Res
; 15(1): 226-37, 2009 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19118050
18.
Blockade of VLA4 sensitizes leukemic and myeloma tumor cells to CD3 redirection in the bone marrow microenvironment.
Blood Cancer J
; 10(6): 65, 2020 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32483120
19.
Teclistamab is an active T cell-redirecting bispecific antibody against B-cell maturation antigen for multiple myeloma.
Blood Adv
; 4(18): 4538-4549, 2020 09 22.
Artigo
Inglês
| MEDLINE | ID: mdl-32956453
20.
A novel C2 domain binding CD33xCD3 bispecific antibody with potent T-cell redirection activity against acute myeloid leukemia.
Blood Adv
; 4(5): 906-919, 2020 03 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32150609