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Physiol Res ; 71(3): 327-339, 2022 07 29.
Artigo em Inglês | MEDLINE | ID: mdl-35904344

RESUMO

Extracellular vesicles are small membrane particles (30-1000 nm) released by Bacteria, Eukaryotes and Archaea. They have been shown to play an important role in intracellular and intercellular communication, within and between kingdoms via transport of bioactive molecules. Thus, they can be involved in altering gene expression and regulation of physiological and pathological processes of the recipient. Their unique properties make extracellular vesicles a perfect candidate vector for targeted drug delivery or a biomarker. For a long time, animal and mainly mammal extracellular vesicles have been used in research. But for plants, there had been speculations about the existence of nanovesicles due to the presence of a cell wall. Today, awareness of plant extracellular vesicles is on the rise and their research has proved they have various functions, such as protein secretion, transport of bioactive molecules or defense against pathogens. Further potential of plant extracellular vesicles is stressed in this review.


Assuntos
Vesículas Extracelulares , Animais , Bactérias , Biomarcadores/metabolismo , Comunicação Celular , Sistemas de Liberação de Medicamentos , Vesículas Extracelulares/metabolismo , Humanos , Mamíferos
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