Detalhe da pesquisa
1.
FDA Approval Summary: Olaparib Monotherapy or in Combination with Bevacizumab for the Maintenance Treatment of Patients with Advanced Ovarian Cancer.
Oncologist
; 26(1): e164-e172, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33017510
2.
Phase I/II Trial of Vandetanib and Bortezomib in Adults with Locally Advanced or Metastatic Medullary Thyroid Cancer.
Oncologist
; 24(1): 16-e14, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30297385
3.
Patients with melanoma treated with an anti-PD-1 antibody beyond RECIST progression: a US Food and Drug Administration pooled analysis.
Lancet Oncol
; 19(2): 229-239, 2018 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29361469
4.
Continued Tumor Reduction of Metastatic Pheochromocytoma/Paraganglioma Harboring Succinate Dehydrogenase Subunit B Mutations with Cyclical Chemotherapy.
Cell Mol Neurobiol
; 38(5): 1099-1106, 2018 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-29623478
5.
Phase I trial of belinostat with cisplatin and etoposide in advanced solid tumors, with a focus on neuroendocrine and small cell cancers of the lung.
Anticancer Drugs
; 29(5): 457-465, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29420340
6.
Regulatory considerations on endpoints in ovarian cancer drug development.
Cancer
; 123(14): 2604-2608, 2017 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28499075
7.
A Phase II Multi-Center Study of Bevacizumab in Combination with Ixabepilone in Subjects with Advanced Renal Cell Carcinoma.
Oncologist
; 22(8): 888-e84, 2017 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28679644
8.
Phase II Clinical Trial of Ixabepilone in Metastatic Cervical Carcinoma.
Oncologist
; 20(7): 725-6, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-26040622
9.
FDA ovarian cancer clinical trial endpoints workshop: A Society of Gynecologic Oncology White Paper.
Gynecol Oncol
; 147(1): 3-10, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28844539
10.
FDA Approval Summary: Pembrolizumab plus Lenvatinib for Endometrial Carcinoma, a Collaborative International Review under Project Orbis.
Clin Cancer Res
; 26(19): 5062-5067, 2020 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32295834
11.
A population pharmacokinetic/toxicity model for the reduction of platelets during a 48-h continuous intravenous infusion of the histone deacetylase inhibitor belinostat.
Cancer Chemother Pharmacol
; 82(3): 565-570, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29951694
12.
FDA Approval Summary: Rucaparib for the Treatment of Patients with Deleterious BRCA Mutation-Associated Advanced Ovarian Cancer.
Clin Cancer Res
; 23(23): 7165-7170, 2017 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28751443
13.
Adrenocortical Cancer: A Molecularly Complex Disease Where Surgery Matters.
Clin Cancer Res
; 22(20): 4989-5000, 2016 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27742785
14.
UGT1A1 genotype-dependent dose adjustment of belinostat in patients with advanced cancers using population pharmacokinetic modeling and simulation.
J Clin Pharmacol
; 56(4): 450-60, 2016 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-26637161
15.
Effects of UGT1A1 genotype on the pharmacokinetics, pharmacodynamics, and toxicities of belinostat administered by 48-hour continuous infusion in patients with cancer.
J Clin Pharmacol
; 56(4): 461-73, 2016 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-26313268
16.
Advancing Clinical Trials to Streamline Drug Development.
Clin Cancer Res
; 21(20): 4527-35, 2015 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26473188
17.
Expansion Cohorts in First-in-Human Solid Tumor Oncology Trials.
Clin Cancer Res
; 21(20): 4545-51, 2015 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26473190
18.
A phase i study of DMS612, a novel bifunctional alkylating agent.
Clin Cancer Res
; 21(4): 721-9, 2015 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25467180
19.
The VEGF inhibitor axitinib has limited effectiveness as a therapy for adrenocortical cancer.
J Clin Endocrinol Metab
; 99(4): 1291-7, 2014 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-24423320
20.
Targeting the epigenome in lung cancer: expanding approaches to epigenetic therapy.
Front Oncol
; 3: 261, 2013 Oct 09.
Artigo
Inglês
| MEDLINE | ID: mdl-24130964