Detalhe da pesquisa
1.
Pregnancy-associated plasma protein-A (PAPP-A) is a key component of an interactive cellular mechanism promoting pulmonary fibrosis.
J Cell Physiol
; 237(4): 2220-2229, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35098542
2.
PAPP-A as a Potential Target in Thyroid Eye Disease.
J Clin Endocrinol Metab
; 2024 May 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38752390
3.
Constitutive expression of pregnancy-associated plasma protein-A in arterial smooth muscle reduces the vascular response to injury in vivo.
Am J Physiol Endocrinol Metab
; 304(2): E139-44, 2013 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23169786
4.
Senescence induces proteolytically-active PAPP-A secretion and association with extracellular vesicles in human pre-adipocytes.
Exp Gerontol
; 172: 112070, 2023 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-36549546
5.
Resistance to age-dependent thymic atrophy in long-lived mice that are deficient in pregnancy-associated plasma protein A.
Proc Natl Acad Sci U S A
; 106(27): 11252-7, 2009 Jul 07.
Artigo
Inglês
| MEDLINE | ID: mdl-19549878
6.
Brain-specific PAPP-A knock-out mice?
Exp Gerontol
; 154: 111548, 2021 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34509589
7.
Transgenic overexpression of pregnancy-associated plasma protein-A in murine arterial smooth muscle accelerates atherosclerotic lesion development.
Am J Physiol Heart Circ Physiol
; 299(2): H284-91, 2010 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-20472761
8.
Genetic and Pharmacological Inhibition of PAPP-A Protects Against Visceral Obesity in Mice.
Endocrinology
; 161(10)2020 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32888014
9.
Metalloproteinase PAPP-A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis.
JCI Insight
; 5(4)2020 02 27.
Artigo
Inglês
| MEDLINE | ID: mdl-31990681
10.
Cellular characterization of human epicardial adipose tissue: highly expressed PAPP-A regulates insulin-like growth factor I signaling in human cardiomyocytes.
Physiol Rep
; 7(4): e14006, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30809969
11.
Overcoming platinum resistance in ovarian cancer by targeting pregnancy-associated plasma protein-A.
PLoS One
; 14(11): e0224564, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31751381
12.
Loss of pregnancy-associated plasma protein A extends lifespan in mice.
Aging Cell
; 6(5): 727-9, 2007 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-17681037
13.
Differential regulation of pregnancy associated plasma protein-A in human coronary artery endothelial cells and smooth muscle cells.
Growth Horm IGF Res
; 18(3): 213-20, 2008 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-17936662
14.
Characterization of mouse pericardial fat: regulation by PAPP-A.
Growth Horm IGF Res
; 42-43: 1-7, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-30025286
15.
Inducible knockdown of pregnancy-associated plasma protein-A gene expression in adult female mice extends life span.
Aging Cell
; 16(4): 895-897, 2017 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28600811
16.
Stress-activated signaling pathways mediate the stimulation of pregnancy-associated plasma protein-A expression in cultured human fibroblasts.
Endocrinology
; 147(2): 885-90, 2006 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-16269458
17.
Comparative gene expression and phenotype analyses of skeletal muscle from aged wild-type and PAPP-A-deficient mice.
Exp Gerontol
; 80: 36-42, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27086066
18.
Targeted Inhibition of Pregnancy-Associated Plasma Protein-A Activity Reduces Atherosclerotic Plaque Burden in Mice.
J Cardiovasc Transl Res
; 9(1): 77-9, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26733326
19.
PAPP-A in normal human mesangial cells: effect of inflammation and factors related to diabetic nephropathy.
J Endocrinol
; 231(1): 71-80, 2016 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27519211
20.
Disruption of insulin-like growth factor-II imprinting during embryonic development rescues the dwarf phenotype of mice null for pregnancy-associated plasma protein-A.
J Endocrinol
; 186(2): 325-31, 2005 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-16079258