Detalhe da pesquisa
1.
Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase.
Proc Natl Acad Sci U S A
; 116(10): 4316-4325, 2019 03 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30782830
2.
Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes.
Hum Mol Genet
; 25(1): 9-23, 2016 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26494904
3.
An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome.
Hum Mol Genet
; 25(18): 3998-4011, 2016 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27466187
4.
Computer-assisted engineering of hyperstable fibroblast growth factor 2.
Biotechnol Bioeng
; 115(4): 850-862, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29278409
5.
Fibroblast growth factor and canonical WNT/ß-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage.
Biochim Biophys Acta
; 1852(5): 839-50, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25558817
6.
Effect of FGFR inhibitors on chicken limb development.
Dev Growth Differ
; 56(8): 555-72, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25280231
7.
Decrease in abundance of apurinic/apyrimidinic endonuclease causes failure of base excision repair in culture-adapted human embryonic stem cells.
Stem Cells
; 31(4): 693-702, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23315699
8.
Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling.
EMBO Mol Med
; 12(11): e11739, 2020 11 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33200460
9.
Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome.
Cell Signal
; 42: 144-154, 2018 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-29030113
10.
Nanodiamonds as "artificial proteins": Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals.
Biomaterials
; 176: 106-121, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29879652
11.
The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases.
Sci Signal
; 11(548)2018 09 18.
Artigo
Inglês
| MEDLINE | ID: mdl-30228226
12.
ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3.
Bone
; 105: 57-66, 2017 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-28826843
13.
Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480.
Oncotarget
; 8(65): 109319-109331, 2017 12 12.
Artigo
Inglês
| MEDLINE | ID: mdl-29312610
14.
One reporter for in-cell activity profiling of majority of protein kinase oncogenes.
Elife
; 62017 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28199182
15.
A novel variant of FGFR3 causes proportionate short stature.
Eur J Endocrinol
; 172(6): 763-70, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-25777271
16.
Receptor tyrosine kinases activate canonical WNT/ß-catenin signaling via MAP kinase/LRP6 pathway and direct ß-catenin phosphorylation.
PLoS One
; 7(4): e35826, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22558232