Detalhe da pesquisa
1.
Preclinical Pharmacokinetics of Fosciclopirox, a Novel Treatment of Urothelial Cancers, in Rats and Dogs.
J Pharmacol Exp Ther
; 370(2): 148-159, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31113837
2.
Intratumoral Injection of Large Surface Area Microparticle Taxanes in Carcinomas Increases Immune Effector Cell Concentrations, Checkpoint Expression, and Synergy with Checkpoint Inhibitors: A Review of Preclinical and Clinical Studies.
Oncol Ther
; 12(1): 31-55, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38289576
3.
Local administration of large surface area microparticle docetaxel to solid carcinomas induces direct cytotoxicity and immune-mediated tumoricidal effects: preclinical and clinical studies.
Drug Deliv Transl Res
; 13(2): 503-519, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36058988
4.
Novel compound C150 inhibits pancreatic cancer through induction of ER stress and proteosome assembly.
Front Oncol
; 12: 870473, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36276125
5.
Novel Compound C150 Inhibits Pancreatic Cancer Cell Epithelial-to-Mesenchymal Transition and Tumor Growth in Mice.
Front Oncol
; 11: 773350, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34976816
6.
Local administration of submicron particle paclitaxel to solid carcinomas induces direct cytotoxicity and immune-mediated tumoricidal effects without local or systemic toxicity: preclinical and clinical studies.
Drug Deliv Transl Res
; 11(5): 1806-1817, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33159289
7.
Fosciclopirox suppresses growth of high-grade urothelial cancer by targeting the γ-secretase complex.
Cell Death Dis
; 12(6): 562, 2021 05 31.
Artigo
Inglês
| MEDLINE | ID: mdl-34059639
8.
Inhaled Submicron Particle Paclitaxel (NanoPac) Induces Tumor Regression and Immune Cell Infiltration in an Orthotopic Athymic Nude Rat Model of Non-Small Cell Lung Cancer.
J Aerosol Med Pulm Drug Deliv
; 32(5): 266-277, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31347939
9.
Pharmacokinetic Profile of Inhaled Submicron Particle Paclitaxel (NanoPac®) in a Rodent Model.
J Aerosol Med Pulm Drug Deliv
; 32(2): 99-109, 2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30359162
10.
Targeted inhibition of histone deacetylase leads to suppression of Ewing sarcoma tumor growth through an unappreciated EWS-FLI1/HDAC3/HSP90 signaling axis.
J Mol Med (Berl)
; 97(7): 957-972, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31025088
11.
Evaluation of intravenous and subcutaneous administration of a novel, excipient-free, nanoparticulate formulation of paclitaxel in dogs with spontaneously occurring neoplasia.
Vet Comp Oncol
; 16(4): 650-657, 2018 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-30182530
12.
Tyr1-ψ[( Z)CFâCH]-Gly2 Fluorinated Peptidomimetic Improves Distribution and Metabolism Properties of Leu-Enkephalin.
ACS Chem Neurosci
; 9(7): 1735-1742, 2018 07 18.
Artigo
Inglês
| MEDLINE | ID: mdl-29648788
13.
In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma.
Oncotarget
; 8(3): 4079-4095, 2017 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-27863422
14.
A phase I study of intraperitoneal nanoparticulate paclitaxel (Nanotax®) in patients with peritoneal malignancies.
Cancer Chemother Pharmacol
; 75(5): 1075-87, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25898813