RESUMO
The electron microscopic appearances of the corneoscleral and iris tissue removed at operation from a child with Hurler disease and glaucoma showed distinctive swollen cells with intracellular inclusions similar to those which are observed in other tissues in these patients and which are due to abnormal lysosomal storages of mucopolysaccharides. Some recent observations on the possible relationship between mucopolysaccharides and the drainage of fluid from the anterior chamber are briefly reviewed and correlated with the present observations. The development of glaucoma in this patient is thought to be associated with the presence of the mucopolysaccharide-containing cells in the region of the aqueous drainage channels.
Assuntos
Glaucoma/etiologia , Mucopolissacaridose I/complicações , Criança , Córnea/ultraestrutura , Feminino , Glaucoma/patologia , Humanos , Corpos de Inclusão/ultraestrutura , Iris/ultraestrutura , Microscopia Eletrônica , Esclera/ultraestrutura , Pele/ultraestruturaRESUMO
Among 200 children who had received routine ophthalmic and orthoptic examinations as part of their evaluation by a multidisciplinary assessment team, it was found that there was a high incidence of ocular defects. These defects included refractive errors (98 children), squint (74 children), nystagmus (15 children), cataract, retinopathy and optic atrophy. This high incidence of ocular defects emphasized the need for the routine ophthalmic examination of developmentally handicapped children in order to detect and treat ocular conditions which might otherwise have gone undetected, and enabled the visual sense of these children to be evaluated in relationship to their general development.
Assuntos
Pessoas com Deficiência , Oftalmopatias/epidemiologia , Transtornos da Visão/epidemiologia , Blefaroptose/epidemiologia , Catarata/epidemiologia , Criança , Pré-Escolar , Humanos , Lactente , Londres , Microftalmia/epidemiologia , Nistagmo Patológico/epidemiologia , Exame Físico , Doenças Retinianas/epidemiologia , Estrabismo/epidemiologiaRESUMO
Among 171 children who received routine ophthalmic and orthoptic examinations as part of their evaluation for suspected or known developmental handicap it was found that there was an unusually high incidence of ocular defects. Especially prevalent were high refractive errors (52%) and squints (40%), but there were also a number of other serious eye defects ranging from nystagmus and cataracts to microphthalmos.Because of this high incidence of eye defects it was considered essential that ophthalmic and orthoptic examinations should be part of the routine evaluation of developmentally handicapped children by the team of workers in an assessment centre.
Assuntos
Oftalmopatias/complicações , Deficiência Intelectual/complicações , Catarata/epidemiologia , Paralisia Cerebral/complicações , Deficiências do Desenvolvimento , Avaliação da Deficiência , Síndrome de Down/complicações , Oftalmopatias/epidemiologia , Oftalmopatias/etiologia , Oftalmopatias/terapia , Humanos , Microftalmia/epidemiologia , Nistagmo Patológico/epidemiologia , Oftalmoscopia , Ortóptica , Erros de Refração/epidemiologia , Estrabismo/epidemiologia , Transtornos da Visão/epidemiologia , Transtornos da Visão/etiologiaRESUMO
The Downs bipolar coagulator is a precision microsurgical instrument for use in cataract surgery and other ophthalmic operations. Its chief advantages are robustness, ease of sterilization, mechanical reliability, and small size. The coagulation is delivered by a fine pair of forceps (designed for ophthalmic use). Precision can be achieved together with the advantage of being able to coagulate fine vessels under a wet film (as in the iris). The coagulation current can be varied and tissue shrinkage is lessened.