Pesquisa | Secretaria de Estado da Saúde

1.

Benzoate X receptor zinc-finger gene switches for drug-inducible regulation of transcription.

Schwimmer, L J; Gonzalez, B; Barbas, C F.

Gene Ther ; 19(4): 458-62, 2012 Apr.

Artigo Inglês | MEDLINE | ID: mdl-21796215

2.

Passive immunization with a human monoclonal antibody protects hu-PBL-SCID mice against challenge by primary isolates of HIV-1.

Gauduin, M C; Parren, P W; Weir, R; Barbas, C F; Burton, D R; Koup, R A.

Nat Med ; 3(12): 1389-93, 1997 Dec.

Artigo Inglês | MEDLINE | ID: mdl-9396610

3.

Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes.

Wagner, J; Lerner, R A; Barbas, C F.

Science ; 270(5243): 1797-800, 1995 Dec 15.

Artigo Inglês | MEDLINE | ID: mdl-8525368

4.

Immune versus natural selection: antibody aldolases with enzymic rates but broader scope.

Barbas, C F; Heine, A; Zhong, G; Hoffmann, T; Gramatikova, S; Björnestedt, R; List, B; Anderson, J; Stura, E A; Wilson, I A; Lerner, R A.

Science ; 278(5346): 2085-92, 1997 Dec 19.

Artigo Inglês | MEDLINE | ID: mdl-9405338

5.

Drug-inducible and simultaneous regulation of endogenous genes by single-chain nuclear receptor-based zinc-finger transcription factor gene switches.

Magnenat, L; Schwimmer, L J; Barbas, C F.

Gene Ther ; 15(17): 1223-32, 2008 Sep.

Artigo Inglês | MEDLINE | ID: mdl-18528430

6.

Synthetic human antibodies.

Barbas, C F.

Nat Med ; 1(8): 837-9, 1995 Aug.

Artigo Inglês | MEDLINE | ID: mdl-7585190

7.

Design of novel sequence-specific DNA-binding proteins.

Segal, D J; Barbas, C F.

Curr Opin Chem Biol ; 4(1): 34-9, 2000 Feb.

Artigo Inglês | MEDLINE | ID: mdl-10679372

8.

Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains.

Dreier, B; Segal, D J; Barbas, C F.

J Mol Biol ; 303(4): 489-502, 2000 Nov 03.

Artigo Inglês | MEDLINE | ID: mdl-11054286

9.

CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range.

Yang, W P; Green, K; Pinz-Sweeney, S; Briones, A T; Burton, D R; Barbas, C F.

J Mol Biol ; 254(3): 392-403, 1995 Dec 01.

Artigo Inglês | MEDLINE | ID: mdl-7490758

10.

Molecular profile of an antibody response to HIV-1 as probed by combinatorial libraries.

Barbas, C F; Collet, T A; Amberg, W; Roben, P; Binley, J M; Hoekstra, D; Cababa, D; Jones, T M; Williamson, R A; Pilkington, G R.

J Mol Biol ; 230(3): 812-23, 1993 Apr 05.

Artigo Inglês | MEDLINE | ID: mdl-8478936

11.

Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries.

Ditzel, H J; Parren, P W; Binley, J M; Sodroski, J; Moore, J P; Barbas, C F; Burton, D R.

J Mol Biol ; 267(3): 684-95, 1997 Apr 04.

Artigo Inglês | MEDLINE | ID: mdl-9126846

12.

Recent advances in phage display.

Barbas, C F.

Curr Opin Biotechnol ; 4(5): 526-30, 1993 Oct.

Artigo Inglês | MEDLINE | ID: mdl-7764201

13.

Phage display of combinatorial antibody libraries.

Rader, C; Barbas, C F.

Curr Opin Biotechnol ; 8(4): 503-8, 1997 Aug.

Artigo Inglês | MEDLINE | ID: mdl-9265732

14.

Custom DNA-binding proteins come of age: polydactyl zinc-finger proteins.

Segal, D J; Barbas, C F.

Curr Opin Biotechnol ; 12(6): 632-7, 2001 Dec.

Artigo Inglês | MEDLINE | ID: mdl-11849947

15.

Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp120 CD4-binding site.

Parren, P W; Ditzel, H J; Gulizia, R J; Binley, J M; Barbas, C F; Burton, D R; Mosier, D E.

AIDS ; 9(6): F1-6, 1995 Jun.

Artigo Inglês | MEDLINE | ID: mdl-7662189

16.

Selection and evolution of high-affinity human anti-viral antibodies.

Barbas, C F; Burton, D R.

Trends Biotechnol ; 14(7): 230-4, 1996 Jul.

Artigo Inglês | MEDLINE | ID: mdl-8771795

17.

Recombinant rabbit Fab with binding activity to type-1 plasminogen activator inhibitor derived from a phage-display library against human alpha-granules.

Lang, I M; Barbas, C F; Schleef, R R.

Gene ; 172(2): 295-8, 1996 Jun 26.

Artigo Inglês | MEDLINE | ID: mdl-8682320

18.

Selection of human anti-hapten antibodies from semisynthetic libraries.

Barbas, C F; Amberg, W; Simoncsits, A; Jones, T M; Lerner, R A.

Gene ; 137(1): 57-62, 1993 Dec 27.

Artigo Inglês | MEDLINE | ID: mdl-8282201

19.

Functional display of human plasminogen-activator inhibitor 1 (PAI-1) on phages: novel perspectives for structure-function analysis by error-prone DNA synthesis.

Pannekoek, H; van Meijer, M; Schleef, R R; Loskutoff, D J; Barbas, C F.

Gene ; 128(1): 135-40, 1993 Jun 15.

Artigo Inglês | MEDLINE | ID: mdl-8508955

20.

Alphav integrins mediate adhesion and migration of breast carcinoma cell lines.

Wong, N C; Mueller, B M; Barbas, C F; Ruminski, P; Quaranta, V; Lin, E C; Smith, J W.

Clin Exp Metastasis ; 16(1): 50-61, 1998 Jan.

Artigo Inglês | MEDLINE | ID: mdl-9502077

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