Detalhe da pesquisa
1.
SEC14-like condensate phase transitions at plasma membranes regulate root growth in Arabidopsis.
PLoS Biol
; 21(9): e3002305, 2023 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-37721949
2.
Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets.
Proc Natl Acad Sci U S A
; 119(24): e2120083119, 2022 06 14.
Artigo
Inglês
| MEDLINE | ID: mdl-35666870
3.
RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function.
Diabetologia
; 2024 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38743124
4.
In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis.
Proc Natl Acad Sci U S A
; 117(5): 2484-2495, 2020 02 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31964806
5.
PtdIns(4,5)P2 is not required for secretory granule docking.
Traffic
; 19(6): 436-445, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29542271
6.
Local PI(4,5)P2 signaling inhibits fusion pore expansion during exocytosis.
Cell Rep
; 42(2): 112036, 2023 02 28.
Artigo
Inglês
| MEDLINE | ID: mdl-36701234
7.
Quantification of Secretory Granule Exocytosis by TIRF Imaging and Capacitance Measurements.
Methods Mol Biol
; 2565: 179-186, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36205894
8.
The ß-cell primary cilium is an autonomous Ca2+ compartment for paracrine GABA signaling.
J Cell Biol
; 222(1)2023 01 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36350286
9.
Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction.
Nat Commun
; 14(1): 4250, 2023 07 17.
Artigo
Inglês
| MEDLINE | ID: mdl-37460527
10.
Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.
Nat Biotechnol
; 40(7): 1042-1055, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35241836
11.
cAMP mediators of pulsatile insulin secretion from glucose-stimulated single beta-cells.
J Biol Chem
; 285(30): 23007-18, 2010 Jul 23.
Artigo
Inglês
| MEDLINE | ID: mdl-20498366
12.
Paracrine control of α-cell glucagon exocytosis is compromised in human type-2 diabetes.
Nat Commun
; 11(1): 1896, 2020 04 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32312960
13.
Release of the styryl dyes from single synaptic vesicles in hippocampal neurons.
J Neurosci
; 28(8): 1894-903, 2008 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-18287506
14.
High extracellular glucose inhibits exocytosis through disruption of syntaxin 1A-containing lipid rafts.
Biochem Biophys Res Commun
; 389(2): 241-6, 2009 Nov 13.
Artigo
Inglês
| MEDLINE | ID: mdl-19716806
15.
Fusion pore regulation by cAMP/Epac2 controls cargo release during insulin exocytosis.
Elife
; 82019 05 20.
Artigo
Inglês
| MEDLINE | ID: mdl-31099751
16.
Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling.
Diabetes
; 68(4): 747-760, 2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30670477
17.
Delay between fusion pore opening and peptide release from large dense-core vesicles in neuroendocrine cells.
Neuron
; 33(2): 287-99, 2002 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-11804575
18.
Syntaxin clusters at secretory granules in a munc18-bound conformation.
Mol Biol Cell
; 29(22): 2700-2708, 2018 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30156474
19.
Glucose-Dependent Granule Docking Limits Insulin Secretion and Is Decreased in Human Type 2 Diabetes.
Cell Metab
; 27(2): 470-478.e4, 2018 02 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29414688
20.
Functional Characterization of Native, High-Affinity GABAA Receptors in Human Pancreatic ß Cells.
EBioMedicine
; 30: 273-282, 2018 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-29606630