Detalhe da pesquisa
1.
ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells.
Cell Commun Signal
; 17(1): 106, 2019 08 23.
Artigo
Inglês
| MEDLINE | ID: mdl-31443721
2.
Preclinical activity of F14512, designed to target tumors expressing an active polyamine transport system.
Invest New Drugs
; 29(1): 9-21, 2011 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-19777159
3.
Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell Activation.
Cancers (Basel)
; 13(8)2021 Apr 13.
Artigo
Inglês
| MEDLINE | ID: mdl-33924378
4.
The Expression of Anti-Müllerian Hormone Type II Receptor (AMHRII) in Non-Gynecological Solid Tumors Offers Potential for Broad Therapeutic Intervention in Cancer.
Biology (Basel)
; 10(4)2021 Apr 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33917111
5.
Circulating CD14high CD16low intermediate blood monocytes as a biomarker of ascites immune status and ovarian cancer progression.
J Immunother Cancer
; 8(1)2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32503947
6.
Antitumor activity of pyridoisoquinoline derivatives F91873 and F91874, novel multikinase inhibitors with activity against the anaplastic lymphoma kinase.
Anticancer Drugs
; 20(5): 364-72, 2009 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-19322071
7.
Synthesis of conjugated spermine derivatives with 7-nitrobenzoxadiazole (NBD), rhodamine and bodipy as new fluorescent probes for the polyamine transport system.
Bioorg Med Chem Lett
; 19(9): 2474-7, 2009 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19332372
8.
Antitumor activity of vinflunine: effector pathways and potential for synergies.
Semin Oncol
; 35(3 Suppl 3): S13-21, 2008 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-18538174
9.
Potential mechanisms of resistance to microtubule inhibitors.
Semin Oncol
; 35(3 Suppl 3): S22-7, 2008 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-18538175
10.
Synthesis and biological evaluation of bengacarboline derivatives.
Bioorg Med Chem Lett
; 18(3): 1212-6, 2008 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18083028
11.
Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3.
Mol Cancer Ther
; 16(7): 1312-1323, 2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28507002
12.
The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells.
Oncotarget
; 8(23): 37061-37079, 2017 Jun 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28427157
13.
The humanized anti-human AMHRII mAb 3C23K exerts an anti-tumor activity against human ovarian cancer through tumor-associated macrophages.
Oncotarget
; 8(59): 99950-99965, 2017 Nov 21.
Artigo
Inglês
| MEDLINE | ID: mdl-29245952
14.
Decreased nucleotide excision repair activity and alterations of topoisomerase IIalpha are associated with the in vivo resistance of a P388 leukemia subline to F11782, a novel catalytic inhibitor of topoisomerases I and II.
Clin Cancer Res
; 10(9): 3156-68, 2004 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-15131057
15.
Antitumor pharmacology -- quo vadis?
Curr Med Chem Anticancer Agents
; 4(5): 389-91, 2004 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-15379689
16.
Novel aspects of natural and modified vinca alkaloids.
Curr Med Chem Anticancer Agents
; 2(1): 55-70, 2002 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-12678751
17.
Inhibition of nucleotide excision repair and sensitisation of cells to DNA cross-linking anticancer drugs by F 11782, a novel fluorinated epipodophylloid.
Biochem Pharmacol
; 63(2): 251-8, 2002 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-11841800
18.
Apoptotic cell death induction by F 11782 a novel dual catalytic inhibitor of topoisomerases I and II.
Biochem Pharmacol
; 65(5): 755-63, 2003 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-12628489
19.
Differential binding to the alpha/beta-tubulin dimer of vinorelbine and vinflunine revealed by nuclear magnetic resonance analyses.
Biochem Pharmacol
; 64(4): 733-40, 2002 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-12167492
20.
Synergistic effects of F 11782, a novel dual inhibitor of topoisomerases I and II, in combination with other anticancer agents.
Cancer Chemother Pharmacol
; 49(6): 479-86, 2002 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-12107553