Detalhe da pesquisa
1.
Enhancement of folate analogue transport inward in L1210 cells during methotrexate therapy of leukemic mice: evidence of the nature of the effect, possible host mediation, and pharmacokinetic significance.
Cancer Res
; 47(20): 5334-9, 1987 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-3498533
2.
Differing specificities for 4-aminofolate analogues of folylpolyglutamyl synthetase from tumors and proliferative intestinal epithelium of the mouse with significance for selective antitumor action.
Cancer Res
; 50(15): 4639-43, 1990 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-2369741
3.
Proposed mechanism of therapeutic selectivity for 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia based upon lower capacities for transport and phosphorylation in proliferative intestinal epithelium compared to tumor cells.
Cancer Res
; 47(3): 700-6, 1987 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-3802076
4.
AIDS-related Kaposi's sarcoma: a phase II study of liposomal doxorubicin. The TLC D-99 Study Group.
Clin Cancer Res
; 5(11): 3432-7, 1999 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-10589755
5.
Carrier-mediated transport of folate compounds in L1210 cells. Initial rate kinetics and extent of duality of entry routes for folic acid and diastereomers of 5-methyltetrahydrohomofolate in the presence of physiological anions.
Biochem Pharmacol
; 36(10): 1659-67, 1987 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-3593392
6.
Synthesis of the 7-hydroxy metabolites of methotrexate and 10-ethyl-10-deazaaminopterin.
J Pharm Sci
; 76(8): 635-8, 1987 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-11002823
7.
Membrane transport and the antineoplastic action of nucleoside analogues.
Cancer Metastasis Rev
; 6(4): 459-80, 1987.
Artigo
Inglês
| MEDLINE | ID: mdl-3327628
8.
Evidence for the facilitated transport of methotrexate polyglutamates into lysosomes derived from S180 cells. Basic properties and specificity for polyglutamate chain length.
J Biol Chem
; 266(18): 11732-7, 1991 Jun 25.
Artigo
Inglês
| MEDLINE | ID: mdl-1711038
9.
Metabolic turnover of methotrexate polyglutamates in lysosomes derived from S180 cells. Definition of a two-step process limited by mediated lysosomal permeation of polyglutamates and activating reduced sulfhydryl compounds.
J Biol Chem
; 267(22): 15356-61, 1992 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-1379226
10.
Facilitated transport of methotrexate polyglutamates into lysosomes derived from S180 cells. Further characterization and evidence for a simple mobile carrier system with broad specificity for homo- or heteropeptides bearing a C-terminal glutamyl moiety.
J Biol Chem
; 267(28): 19986-91, 1992 Oct 05.
Artigo
Inglês
| MEDLINE | ID: mdl-1383199
11.
Altered molecular properties of tubulin in a multidrug-resistant variant of Chinese hamster cells selected for resistance to vinca alkaloids.
J Cell Physiol
; 136(2): 341-7, 1988 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-3045133