Detalhe da pesquisa
1.
S1PR1 signaling attenuates apoptosis of retinal ganglion cells via modulation of cJun/Bim cascade and Bad phosphorylation in a mouse model of glaucoma.
FASEB J
; 37(1): e22710, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36520045
2.
Neuroserpin gene therapy inhibits retinal ganglion cell apoptosis and promotes functional preservation in glaucoma.
Mol Ther
; 31(7): 2056-2076, 2023 07 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36905120
3.
Neuroserpin, a crucial regulator for axogenesis, synaptic modelling and cell-cell interactions in the pathophysiology of neurological disease.
Cell Mol Life Sci
; 79(3): 172, 2022 Mar 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35244780
4.
Dicer up-regulation by inhibition of specific proteolysis in differentiating monocytic cells.
Proc Natl Acad Sci U S A
; 117(15): 8573-8583, 2020 04 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32220961
5.
Fingolimod effects on the brain are mediated through biochemical modulation of bioenergetics, autophagy, and neuroinflammatory networks.
Proteomics
; 22(19-20): e2100247, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35866514
6.
Modulation of microRNA processing by 5-lipoxygenase.
FASEB J
; 35(2): e21193, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33205517
7.
Mitochondrial dysfunction in Alzheimer's disease - a proteomics perspective.
Expert Rev Proteomics
; 18(4): 295-304, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33874826
8.
Evolving geographic diversity in SARS-CoV2 and in silico analysis of replicating enzyme 3CLpro targeting repurposed drug candidates.
J Transl Med
; 18(1): 278, 2020 07 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32646487
9.
P2X7 Receptor Regulates Internalization of Antimicrobial Peptide LL-37 by Human Macrophages That Promotes Intracellular Pathogen Clearance.
J Immunol
; 195(3): 1191-201, 2015 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26116509
10.
Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis.
Proc Natl Acad Sci U S A
; 111(31): 11371-6, 2014 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25034252
11.
Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein.
FASEB J
; 29(12): 5029-43, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26289316
12.
Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase.
J Pharmacol Exp Ther
; 355(1): 108-16, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-26283693
13.
The role of myelin in neurodegeneration: implications for drug targets and neuroprotection strategies.
Rev Neurosci
; 35(3): 271-292, 2024 Apr 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37983528
14.
Glial Cell Activation and Immune Responses in Glaucoma: A Systematic Review of Human Postmortem Studies of the Retina and Optic Nerve.
Aging Dis
; 2024 Mar 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38502591
15.
Quantitative Proteomics Reveal Region-Specific Alterations in Neuroserpin-Deficient Mouse Brain and Retina: Insights into Serpini1 Function.
Proteomes
; 12(1)2024 Mar 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38535505
16.
Tau modulation through AAV9 therapy augments Akt/Erk survival signalling in glaucoma mitigating the retinal degenerative phenotype.
Acta Neuropathol Commun
; 12(1): 89, 2024 Jun 07.
Artigo
Inglês
| MEDLINE | ID: mdl-38845058
17.
Spatial and temporal aspects and the interplay of Grb14 and protein tyrosine phosphatase-1B on the insulin receptor phosphorylation.
Cell Commun Signal
; 11: 96, 2013 Dec 18.
Artigo
Inglês
| MEDLINE | ID: mdl-24350791
18.
Anti-inflammatory Effects of Siponimod in a Mouse Model of Excitotoxicity-Induced Retinal Injury.
Mol Neurobiol
; 60(12): 7222-7237, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37542647
19.
Siponimod exerts neuroprotective effects on the retina and higher visual pathway through neuronal S1PR1 in experimental glaucoma.
Neural Regen Res
; 18(4): 840-848, 2023 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-36204852
20.
Signalling pathways and cell death mechanisms in glaucoma: Insights into the molecular pathophysiology.
Mol Aspects Med
; 94: 101216, 2023 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37856930