Detalhe da pesquisa
1.
Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis.
Proc Natl Acad Sci U S A
; 116(19): 9521-9526, 2019 05 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31019090
2.
PNPLA3, CGI-58, and Inhibition of Hepatic Triglyceride Hydrolysis in Mice.
Hepatology
; 69(6): 2427-2441, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30802989
3.
The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation.
Hepatology
; 66(4): 1111-1124, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28520213
4.
Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins.
J Biol Chem
; 291(20): 10659-76, 2016 May 13.
Artigo
Inglês
| MEDLINE | ID: mdl-27013658
5.
Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis.
Hepatology
; 61(1): 108-18, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-24917523
6.
Rab7 mutants associated with Charcot-Marie-Tooth disease cause delayed growth factor receptor transport and altered endosomal and nuclear signaling.
J Biol Chem
; 288(2): 1135-49, 2013 Jan 11.
Artigo
Inglês
| MEDLINE | ID: mdl-23188822
7.
Rapid parallel flow cytometry assays of active GTPases using effector beads.
Anal Biochem
; 442(2): 149-57, 2013 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23928044
8.
Hepatocyte mARC1 promotes fatty liver disease.
JHEP Rep
; 5(5): 100693, 2023 May.
Artigo
Inglês
| MEDLINE | ID: mdl-37122688
10.
RAB18 modulates autophagy in human stellate cells.
J Clin Lipidol
; 13(5): 832-838, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31563421
11.
A Pan-GTPase Inhibitor as a Molecular Probe.
PLoS One
; 10(8): e0134317, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26247207
12.
Rab7 mutants associated with Charcot-Marie-Tooth disease exhibit enhanced NGF-stimulated signaling.
PLoS One
; 5(12): e15351, 2010 Dec 09.
Artigo
Inglês
| MEDLINE | ID: mdl-21151572