Detalhe da pesquisa
1.
YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis.
Nucleic Acids Res
; 47(6): 3127-3141, 2019 04 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30605522
2.
Using the structural diversity of RNA: protein interfaces to selectively target RNA with small molecules in cells: methods and perspectives.
Front Mol Biosci
; 10: 1298441, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-38033386
3.
Targeting RNA:protein interactions with an integrative approach leads to the identification of potent YBX1 inhibitors.
Elife
; 122023 01 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36651723
4.
Design, synthesis and biological evaluation of quinoline-2-carbonitrile-based hydroxamic acids as dual tubulin polymerization and histone deacetylases inhibitors.
Eur J Med Chem
; 240: 114573, 2022 Oct 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35797900
5.
Targeting Degradation of EGFR through the Allosteric Site Leads to Cancer Cell Detachment-Promoted Death.
Cancers (Basel)
; 11(8)2019 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31374910
6.
Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A-4.
J Med Chem
; 61(15): 6574-6591, 2018 Aug 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30004697
7.
Cucurbitacin I elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-kinase.
Biochem Pharmacol
; 102: 45-63, 2016 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26707799
8.
α- and ß-hydrazino acid-based pseudopeptides inhibit the chymotrypsin-like activity of the eukaryotic 20S proteasome.
Eur J Med Chem
; 70: 505-24, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24185380
9.
Elucidation of the ATP7B N-domain Mg2+-ATP coordination site and its allosteric regulation.
PLoS One
; 6(10): e26245, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-22046264