Detalhe da pesquisa
1.
Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation.
J Biol Chem
; 292(43): 17963-17974, 2017 10 27.
Artigo
Inglês
| MEDLINE | ID: mdl-28860188
2.
The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2.
J Lipid Res
; 53(6): 1106-16, 2012 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-22493088
3.
A novel fluorogenic substrate for the measurement of endothelial lipase activity.
J Lipid Res
; 52(2): 374-82, 2011 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-21062953
4.
Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution.
Protein Sci
; 20(4): 670-83, 2011 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-21308848
5.
Potency variation of small-molecule chymase inhibitors across species.
Biochem Pharmacol
; 80(7): 1033-41, 2010 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20599788
6.
Structural basis for elastolytic substrate specificity in rodent alpha-chymases.
J Biol Chem
; 283(1): 427-436, 2008 Jan 04.
Artigo
Inglês
| MEDLINE | ID: mdl-17981788
7.
Protein engineering of the colony-stimulating factor-1 receptor kinase domain for structural studies.
J Biol Chem
; 282(6): 4085-93, 2007 Feb 09.
Artigo
Inglês
| MEDLINE | ID: mdl-17132625
8.
Effect of construct design on MAPKAP kinase-2 activity, thermodynamic stability and ligand-binding affinity.
Arch Biochem Biophys
; 449(1-2): 47-56, 2006 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-16620770
9.
Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors.
Bioorg Med Chem Lett
; 16(1): 123-8, 2006 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-16236500