Detalhe da pesquisa
1.
Optimization of 8-oxoadenines with toll-like-receptor 7 and 8 activity.
Bioorg Med Chem Lett
; 30(6): 126984, 2020 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32001135
2.
Efficient tin-mediated synthesis of lysophospholipid conjugates of a TLR7/8-active imidazoquinoline.
Tetrahedron Lett
; 57(19): 2093-2096, 2016 May 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32863447
3.
Phospholipidation of TLR7/8-active imidazoquinolines using a tandem phosphoramidite method.
Tetrahedron Lett
; 57(19): 2063-2066, 2016 May 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32863446
4.
Characterization of TRIF selectivity in the AGP class of lipid A mimetics: role of secondary lipid chains.
Bioorg Med Chem Lett
; 25(3): 547-53, 2015 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25553892
5.
Structural requirements for TLR7-selective signaling by 9-(4-piperidinylalkyl)-8-oxoadenine derivatives.
Bioorg Med Chem Lett
; 25(6): 1318-23, 2015 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25698055
6.
Co-Delivery of a Novel Lipidated TLR7/8 Agonist and Hemagglutinin-Based Influenza Antigen Using Silica Nanoparticles Promotes Enhanced Immune Responses.
Pharmaceutics
; 16(1)2024 Jan 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38258117
7.
A lipidated TLR7/8 adjuvant enhances the efficacy of a vaccine against fentanyl in mice.
NPJ Vaccines
; 8(1): 97, 2023 Jul 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37429853
8.
Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination.
Sci Rep
; 12(1): 16860, 2022 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36258023
9.
Novel Lipidated Imidazoquinoline TLR7/8 Adjuvants Elicit Influenza-Specific Th1 Immune Responses and Protect Against Heterologous H3N2 Influenza Challenge in Mice.
Front Immunol
; 11: 406, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-32210973
10.
Synthetic Toll-like Receptors 7 and 8 Agonists: Structure-Activity Relationship in the Oxoadenine Series.
ACS Omega
; 4(13): 15665-15677, 2019 Sep 24.
Artigo
Inglês
| MEDLINE | ID: mdl-31572869
11.
The 'Ethereal' nature of TLR4 agonism and antagonism in the AGP class of lipid A mimetics.
Bioorg Med Chem Lett
; 18(20): 5350-4, 2008 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-18835160
12.
Evaluation of novel synthetic TLR7/8 agonists as vaccine adjuvants.
Vaccine
; 34(36): 4304-12, 2016 08 05.
Artigo
Inglês
| MEDLINE | ID: mdl-27402566
13.
Regio- and Stereoselective Synthesis of beta-D-Gluco-, alpha-L-Ido-, and alpha-L-Altropyranosiduronic Acids from Delta(4)-Uronates.
J Org Chem
; 64(1): 144-152, 1999 Jan 08.
Artigo
Inglês
| MEDLINE | ID: mdl-11674096
14.
Inhibition of apolipoprotein E-related neurotoxicity by glycosaminoglycans and their oligosaccharides.
Biochemistry
; 41(25): 8203-11, 2002 Jun 25.
Artigo
Inglês
| MEDLINE | ID: mdl-12069613