Detalhe da pesquisa
1.
Brain-penetrant cyanoindane and cyanotetralin inhibitors of G2019S-LRRK2 kinase activity.
Bioorg Med Chem Lett
; 95: 129487, 2023 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37734423
2.
Fine tuning for success in structure-based virtual screening.
J Comput Aided Mol Des
; 35(12): 1195-1206, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34799816
3.
Cyclopropane derivatives as potential human serine racemase inhibitors: unveiling novel insights into a difficult target.
J Enzyme Inhib Med Chem
; 31(4): 645-52, 2016 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-26133542
4.
LiGen: a high performance workflow for chemistry driven de novo design.
J Chem Inf Model
; 53(6): 1518-27, 2013 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-23617275
5.
Use of experimental design to optimize docking performance: the case of LiGenDock, the docking module of LiGen, a new de novo design program.
J Chem Inf Model
; 53(6): 1503-17, 2013 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-23590204
6.
Discovery of a Potent, Selective, and Orally Bioavailable Tool Compound for Probing the Role of Lysophosphatidic Acid Type 2 Receptor Antagonists in Fibrotic Disorders.
J Med Chem
; 66(8): 5622-5656, 2023 04 27.
Artigo
Inglês
| MEDLINE | ID: mdl-37017110
7.
Aspergillus fumigatus tryptophan metabolic route differently affects host immunity.
Cell Rep
; 34(4): 108673, 2021 01 26.
Artigo
Inglês
| MEDLINE | ID: mdl-33503414
8.
Selective Inhibitors of G2019S-LRRK2 Kinase Activity.
J Med Chem
; 63(23): 14821-14839, 2020 12 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33197196
9.
Accepting the Invitation to Open Innovation in Malaria Drug Discovery: Synthesis, Biological Evaluation, and Investigation on the Structure-Activity Relationships of Benzo[b]thiophene-2-carboxamides as Antimalarial Agents.
J Med Chem
; 60(5): 1959-1970, 2017 03 09.
Artigo
Inglês
| MEDLINE | ID: mdl-28128956
10.
Rational Design, Synthesis, and Preliminary Structure-Activity Relationships of α-Substituted-2-Phenylcyclopropane Carboxylic Acids as Inhibitors of Salmonella typhimurium O-Acetylserine Sulfhydrylase.
J Med Chem
; 59(6): 2567-78, 2016 Mar 24.
Artigo
Inglês
| MEDLINE | ID: mdl-26894308
11.
Uma revisita ao desejo do psicanalista em O banquete de Platão, segundo o legado de Freud e Lacan / A revisit to the analyst's desire at Plato's The banquet, according to the legacy of Freud and Lacan / Una revisita al deseo del psicoanalista en El banquete de Platón, de acuerdo con el legado de Freud y Lacan
Rev. psicanal
; 27(3): 605-625, Dezembro 2020.
Artigo
Português
| LILACS, Index Psi (psicologia) | ID: biblio-1252774
12.
Further insights into the SAR of α-substituted cyclopropylamine derivatives as inhibitors of histone demethylase KDM1A.
Eur J Med Chem
; 92: 377-86, 2015 Mar 06.
Artigo
Inglês
| MEDLINE | ID: mdl-25585008
13.
2-Aminonicotinic acid 1-oxides are chemically stable inhibitors of quinolinic acid synthesis in the mammalian brain: a step toward new antiexcitotoxic agents.
J Med Chem
; 56(23): 9482-95, 2013 Dec 12.
Artigo
Inglês
| MEDLINE | ID: mdl-24274468
14.
Molecular dynamics simulations and docking studies on 3D models of the heterodimeric and homodimeric 5-HT(2A) receptor subtype.
Future Med Chem
; 3(6): 665-81, 2011 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-21554074