RESUMO
OBJECTIVES: To assess management options for ethmoid adenocarcinoma. STUDY DESIGN: Retrospective review over 28 years. PATIENTS AND METHODS: Ninety-five patients were included. Statistical analysis using the Kaplan-Meier method was performed to establish survival rates, and univariate analysis to determine prognostic factors. Independent chi(2) test was used to compare survival rates between T3 and T4a stages operated by transfacial and craniofacial approaches, respectively. RESULTS: Mean age was 64 years, and 76% patients were stage T3 or T4. Three patients had node metastasis, none of whom had distant metastases at time of diagnosis. Eighty-three percent of patients received surgery and adjuvant radiotherapy on tumor bed. Mean follow-up was 5 years. The recurrence and metastasis rate were 31 and 9% at median time of 3 years, respectively. The disease-specific 5- and 10-year survival rates were 78 and 64%, respectively. The disease-free survival rate was 61 and 44%, respectively, at the same time points. Meningo-encephalic (P = 10(-8)), orbit or infratemporal fossae (P = 0.046), and frontal sinus extension (P = 0.02) negatively impacted survival. There was no statistically significant difference in survival rate between T3 and T4a. CONCLUSIONS: Our data suggest that less surgical treatment may be needed than is usually advocated for T1-T4a tumors and that surgery alone may be appropriate for T1-T3 tumors that have been resected with adequate margins in those patients for whom excellent follow-up is anticipated. No neck irradiation is indicated for N0 disease.
Assuntos
Adenocarcinoma/terapia , Neoplasias dos Seios Paranasais/terapia , Adenocarcinoma/mortalidade , Adenocarcinoma/secundário , Adulto , Idoso , Idoso de 80 Anos ou mais , Terapia Combinada , Seio Etmoidal , Feminino , Seguimentos , Humanos , Metástase Linfática , Masculino , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/patologia , Recidiva Local de Neoplasia/radioterapia , Recidiva Local de Neoplasia/cirurgia , Estadiamento de Neoplasias , Neoplasias dos Seios Paranasais/mortalidade , Neoplasias dos Seios Paranasais/patologia , Dosagem Radioterapêutica , Estudos Retrospectivos , Procedimentos Cirúrgicos Operatórios , Taxa de Sobrevida , Resultado do TratamentoRESUMO
Severe forms of otosclerosis known as far-advanced otosclerosis (FAO) can lead to severe to profound sensorineural hearing loss and can justify cochlear implantation. Because of the pathophysiology of otosclerosis, patients implanted for FAO may experience an increased rate of complications, such as facial nerve stimulation or electrode dislocation, and may have poorer hearing outcomes than expected. This retrospective study aimed to compare cochlear implantation hearing outcomes, surgical difficulties and complications in FAO patients versus non-FAO patients. Moreover, we evaluated whether high resolution computed tomography (CT scan) findings were predictive of perioperative problems, complications and hearing outcomes. FAO patients were diagnosed based on medical history, examination and CT scan. Thirty-five ears from FAO patients were compared to 38 control ears. Audiometric results were assessed at least 12 months after implantation by pure tone average, speech reception threshold, monosyllabic and disyllabic word recognition score (WRS) and Central Institute for the Deaf (CID) sentences test. Complications and surgical difficulties were compiled. CT scan findings were categorised within 3 grades of otosclerotic extension. No significant difference was found between FAO and non-FAO hearing outcomes, except that monosyllabic WRS were lower for FAO patients, especially those who underwent previous stapedotomy. Facial nerve symptomatology occurred in 8.6% of FAO patients; among these, one required explantation-reimplantation surgery. 86% of FAO implanted patients had retrofenestral extension on CT. These were associated with poorer disyllabic WRS (51% vs 68%, p < 0.05) than those with only fenestral involvement. Although not significant, high grade of severity on CT tended to be associated with surgical difficulties and complications. Cochlear implantation in FAO patients is an effective treatment technique. Though the overall complication rate is low, it tends to be higher in cases of severe extension on CT. Patient counselling should be adjusted accordingly.
Assuntos
Implante Coclear , Otosclerose/cirurgia , Complicações Pós-Operatórias/epidemiologia , Idoso , Audiometria , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Otosclerose/diagnóstico por imagem , Valor Preditivo dos Testes , Estudos Retrospectivos , Índice de Gravidade de Doença , Tomografia Computadorizada por Raios X , Resultado do TratamentoRESUMO
OBJECTIVES: To evaluate functional outcome in 64 cases of facial paralysis following temporal bone fracture and discuss decisive arguments leading either to medical treatment or surgical management. METHODS: Sixty-four patients suffering from post-traumatic facial paralysis were managed between 1995 and 2003: 38 (59%) were given medical treatment and 26 (41%) underwent surgery. A combined middle fossa and transmastoid approach was mostly used (58%). Electrophysiological testing and CT scan results were the main points of the decision algorithm. RESULTS: Electroneuromyography seems to be the most accurate exploration for guiding treatment. Good results (grades I to II on the House and Brackmann scale) were obtained in 63% of cases after medical management and in 39% of cases after surgical treatment. Grades III or IV were obtained in 13% of medically-treated patients and 42% of surgically-treated patients. CONCLUSION: Management of facial paralysis following temporal bone fracture in accordance with electrophysiological testing (evoked EMG) together with CT scan findings enabled accurate indications for surgical treatment. A good grade I or II result can be expected after medical management. A grade III is at best reached after nerve anastomosis.
Assuntos
Paralisia Facial/etiologia , Osso Temporal/lesões , Adolescente , Adulto , Idoso , Anti-Inflamatórios/uso terapêutico , Audiometria/métodos , Criança , Terapia Combinada , Eletromiografia , Paralisia Facial/diagnóstico , Paralisia Facial/terapia , Feminino , Humanos , Masculino , Metilprednisolona/uso terapêutico , Pessoa de Meia-Idade , Prednisona/uso terapêutico , Osso Temporal/cirurgia , Tomografia Computadorizada por Raios X , Ferimentos e Lesões/complicações , Ferimentos e Lesões/terapiaRESUMO
OBJECTIVES: To review and study the management of CPA meningiomas through the experience of an otoneurosurgical team. MATERIAL AND METHODS: Fourty-two patients (44 meningiomas) were considered. Seventy-seven per cent of tumors (34 cases) were operated on; 6 tumors (14.6%) were exclusively irradiated using fractionated radiation therapy (FRT) and four only surveyed (9,8%). RESULTS: transpetrosal approaches were exclusively used. These were translabyrinthine (TLA) in 47%, widened retrolabyrinthine (WRLA) in 41% of cases, transcochlear approach (TCA) in three cases and a middle fossa in one. A transtentorial approach was combined in 35% of cases (8 TLA, 4 WRLA). Surgical removal was incomplete in 11,8% of cases; in 3 cases growing tumor was treated by FRT included one case of anaplasic tumor Postoperative complications were: 1 meningitis, 1 wound abscess, 2 hydrocephalus (6%) and 4 CSF fistulas (12%). No complications have been observed during the last 7 years (21 cases). House and Brackmann Grade 1 or 2 facial function was obtained in 59% of cases (but 10 patients had a preoperative facial nerve paresis). A normal or subnormal AAO-HNS Class A-B Hearing could be preserved in 57% of WRLA. Radiation therapy allowed tumor shrinkage in all cases. In 3 cases this regression was of more than 50%. CONCLUSION: Surgery is the gold standard in treating CPA meningiomas. Transpetrosal approaches and particularly WRLA pure or combined to a transtentorial approach are for us the best way to remove these tumors in preserving hearing and facial nerve function. When hearing is poor or when tumor extension to the clivus or the premeatal area is consistent a TLA is either planned preoperatively or obtained from a WRLA.
Assuntos
Ângulo Cerebelopontino/efeitos da radiação , Ângulo Cerebelopontino/cirurgia , Neoplasias Meníngeas/radioterapia , Neoplasias Meníngeas/cirurgia , Meningioma/radioterapia , Meningioma/cirurgia , Adulto , Idoso , Ângulo Cerebelopontino/patologia , Terapia Combinada , Feminino , Humanos , Imageamento por Ressonância Magnética , Masculino , Neoplasias Meníngeas/patologia , Meningioma/patologia , Pessoa de Meia-Idade , Estudos RetrospectivosRESUMO
From January 1986 to March 1989, 20 patients with stage III and IV cerebello-pontine angle neurinomas were treated with external fractionated radiation therapy; seven patients had phacomatosis. Indications for radiation therapy were as follows: (a) poor general condition or old age contraindicating surgery, 10 patients; (b) hearing preservation in bilateral neurinomas after contralateral tumor removal, 5 patients; (c) partial resection or high risk of recurrence after subsequent surgery for relapse, 4 patients; (d) non-surgical relapse, 1 patient. Most patients were irradiated with a 9 MV linear accelerator. A 3 to 4-field technique with 5 x 5 cm portals was used. Doses were calculated on a 95% isodose and were given 5 days a week for a mean total dose of 5140 cGy (180 cGy/fraction). Median follow-up from radiation therapy was 30 months (7 to 46); 4 patients died, 2 with progressive disease. Two patients underwent total tumor removal after radiation therapy (1 stable and 1 growing tumor). On the whole, 14 tumors remained stable, 3 decreased in size, and 3 progressed. CT scan or NMR tumor changes consistent with partial tumor necrosis appeared in four cases. Hearing preservation was obtained in 3/5 hearing patients with phacomatosis. When surgery is not indicated or incomplete, fractionated radiation therapy appears to be an effective and well-tolerated treatment for stage III and IV neurinomas. Hearing can be preserved.
Assuntos
Neoplasias Cerebelares/radioterapia , Ângulo Cerebelopontino , Neurilemoma/radioterapia , Neurofibromatose 1/radioterapia , Neuroma Acústico/radioterapia , Adulto , Idoso , Neoplasias Cerebelares/epidemiologia , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Neurilemoma/epidemiologia , Neurofibromatose 1/epidemiologia , Neuroma Acústico/epidemiologia , Estudos RetrospectivosRESUMO
PURPOSE: To reevaluate long-term results of fractionated radiation therapy (RT) in a previously published series of cerebello-pontine angle neurinomas (CPA). METHODS AND MATERIALS: From January 1986 to May 1992, 24 patients with Stage III and IV CPA neurinomas were treated with external fractionated RT; 7 patients had phacomatosis. One patient was irradiated on both sides and indications for radiotherapy were as follows: (a) poor general condition or old age contraindicating surgery, 14 cases; (b) hearing preservation in bilateral neurinomas after contralateral tumor removal, 5 cases; (c) partial resection or high risk of recurrence after subsequent surgery for relapse, 4 cases; (d) nonsurgical relapse, 2 cases. Most patients were irradiated with 9 MV photons. A three- to four-field technique with coned-down portals was used. Doses were calculated on a 95% isodose and were given 5 days a week for a mean total dose of 51 Gy (1.80 Gy/fraction). RESULTS: Median follow-up from RT was 60 months (7 to 84); five patients died, two with progressive disease. Two patients underwent total tumor removal after RT (one stable and one growing tumor). On the whole, tumor shrinkage was observed in 9 patients (36%), stable disease in 13 (52%), and tumor progression in 3. Hearing was maintained in 3 out of 5 hearing patients with phacomatosis. CONCLUSION: Fractionated RT appears to be an effective and well-tolerated treatment for Stage III and IV CPA neurinomas. Hearing can be preserved for a long time.
Assuntos
Neoplasias Cerebelares/radioterapia , Ângulo Cerebelopontino , Neurilemoma/radioterapia , Adulto , Idoso , Idoso de 80 Anos ou mais , Neoplasias Cerebelares/diagnóstico por imagem , Neoplasias Cerebelares/patologia , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Neurilemoma/diagnóstico por imagem , Neurilemoma/patologia , Dosagem Radioterapêutica , Tomografia Computadorizada por Raios XRESUMO
OBJECT: The goal of this study was to assess the clinical results of hypoglossal-facial nerve attachment (HFA), which was primarily performed in patients following excision of tumors of the cerebellopontine angle. In six of the patients a new side-to-end procedure was used. METHODS: The authors have performed a retrospective study of 33 patients who underwent HFA, including 24 classic end-to-end, three May, and six side-to-end procedures. For the latter procedure, a hemihypoglossal-facial nerve attachment was performed by rerouting the intratemporal facial nerve; this avoided the jump-cable graft used in May's technique. The goal of the new procedure is to reduce the incidence of morbidity due to hemilingual paralysis (difficulty in chewing, speaking, and swallowing). The incidence of hemilingual paralysis was evaluated based on the findings of a questionnaire that was completed by the patients. The patient's facial mobility was assessed using the House and Brackmann grading system and the author's analytic scoring system. CONCLUSIONS: The HFA offers good functional results. Of the 28 cases evaluated, nine had House and Brackmann Grade III, 17 Grade IV, and only two Grade V at 18 months. When the new technique of side-to-end hemihypoglossal-facial nerve attachment was used, there was considerable reduction, if not complete disappearance, of lingual morbidity and the facial functional results were constant and satisfactory: there were five patients with House and Brackmann Grade III and one with Grade IV, and their mean percentage of facial mobility was 43.3%.
Assuntos
Nervo Facial/cirurgia , Nervo Hipoglosso/cirurgia , Adolescente , Adulto , Idoso , Neoplasias Cerebelares/cirurgia , Ângulo Cerebelopontino/cirurgia , Criança , Deglutição/fisiologia , Músculos Faciais/fisiopatologia , Paralisia Facial/etiologia , Feminino , Humanos , Incidência , Nervo Lingual/fisiopatologia , Masculino , Mastigação/fisiologia , Pessoa de Meia-Idade , Paralisia/etiologia , Satisfação do Paciente , Complicações Pós-Operatórias/prevenção & controle , Recuperação de Função Fisiológica , Estudos Retrospectivos , Fala/fisiologia , Inquéritos e Questionários , Osso Temporal/inervação , Língua/inervação , Resultado do TratamentoRESUMO
For many years, the retrolabyrinthine approach has been limited to functional surgery of the cerebellopontine angle (CPA). As a result of the increased surgical exposure, particularly the opening of the internal auditory meatus (IAM), the widened retrolabyrinthine technique permits tumor excision from both the CPA and the IAM, regardless of the histological nature of the tumor. The authors have treated 60 acoustic neuromas of varying sizes via this approach (6% intrameatal tumors; 30% > 25 mm in diameter). The postoperative mortality rate was 0%. The risk of fistula formation was 3.3%, and 3.3% of the patients suffered from postoperative meningitis. The results for facial nerve function were equivalent to those obtained previously via a widened translabyrinthine approach and those in a series treated via a suboccipital approach (80% with Grades I and II, 15% with Grade III, and 5% with Grades V and VI). One patient (1.7%) required a secondary hypoglossal-facial nerve anastomosis and had attained a Grade IV result 6 months later. Postoperatively 21.7% of these patients maintained socially useful hearing and 20% had mediocre hearing. Socially useful hearing was preserved in 50% of a subgroup of 20 patients who had both good preoperative hearing and a tumor that involved less than half of the IAM regardless of its volume. Additionally, 15% had mediocre hearing that could be improved with hearing aids. Because of its efficacy in preserving hearing, the authors favor the retrolabyrinthine over the occipital approach, with the latter being considered less subtle and more aggressive.
Assuntos
Neuroma Acústico/cirurgia , Adulto , Idoso , Anatomia Artística , Surdez/etiologia , Orelha Interna/diagnóstico por imagem , Orelha Interna/patologia , Face/fisiopatologia , Feminino , Humanos , Imageamento por Ressonância Magnética , Masculino , Ilustração Médica , Pessoa de Meia-Idade , Morbidade , Neuroma Acústico/diagnóstico , Neuroma Acústico/epidemiologia , Complicações Pós-Operatórias , Tomografia Computadorizada por Raios XRESUMO
OBJECTIVE: The goal of this study was to review decision factors and overall results regarding surgical and nonsurgical management of post-traumatic facial nerve paralysis (FP). STUDY DESIGN: A retrospective study and literature review were performed. METHODS: Between 1984 and 1990, 115 cases of post-traumatic FP were handled. Patients were evaluated through clinical, audiologic, radiologic, and electromyogram assessment. Depending on examination results, patients were treated either medically or surgically through total facial nerve decompression. RESULTS: Forty-nine of the 50 medically treated patients experienced a normal or subnormal facial function recovery (grade I-II). Of the 65 (56.5%) surgically treated patients, 52 (80%) had immediate, 2 had delayed, and 11 (17%) had unknown delay-associated FP. The approaches chosen were middle fossa and transmastoid (75.3%), translabyrinthine (10.7%), or pure transmastoid according to facial nerve nonmotor branch evaluation, hearing, location of the fracture line, and the patient's general condition. Lesions were predominantly found in the geniculate ganglion area (66.2%). A nerve gap was found in only 13.8% of the cases. At 2 years after surgery, 93.8% had a grade I to III recovery. None had grade V or VI. CONCLUSION: The rarity of severe nerve lesions encountered in surgically treated patients raises the question of better selection of candidates for surgery. Surgery is clearly indicated when FP is total, is of immediate onset, and is associated with a bad prognosis electromyogram pattern. In other settings, decisions are to be made based on high-resolution CT data and electromyogram results, thanks to a clinical survey and second electromyogram evaluation.
Assuntos
Paralisia Facial/etiologia , Paralisia Facial/terapia , Fraturas Ósseas/complicações , Osso Temporal/lesões , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Terapia Combinada , Terapia por Estimulação Elétrica/métodos , Eletromiografia , Feminino , Seguimentos , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/terapia , Humanos , Masculino , Metilprednisolona/administração & dosagem , Pessoa de Meia-Idade , Procedimentos Neurocirúrgicos/métodos , Modalidades de Fisioterapia/métodos , Estudos Retrospectivos , Sensibilidade e Especificidade , Índice de Gravidade de Doença , Osso Temporal/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Resultado do TratamentoRESUMO
The authors developed a research program on piezoelectric middle ear implants. A piezoelectric vibrator was implanted on guinea pigs, enabling piezoelectric auditory-evoked recording. The shape and sizes of a vibrator for humans were determined by a human temporal bone study. These human-type vibrators showed good performances in vitro. A particular vibrator for humans that can be implanted on the stapes' head, without irreversibly interrupting the ossicular chain, was designed by the authors.
Assuntos
Correção de Deficiência Auditiva , Ossículos da Orelha , Orelha Média/cirurgia , Auxiliares de Audição , Próteses e Implantes , Animais , Orelha Média/fisiopatologia , Potenciais Evocados Auditivos , Cobaias , Transtornos da Audição/fisiopatologia , Humanos , Técnicas In Vitro , Osso PetrosoRESUMO
Nasal polyposis (NP) is a common condition in patients consulting ENT practitioners in France. A multicenter prospective study was performed to evaluate symptoms, demography, environmental factors, personal and family history and associated conditions like asthma, and food or drugs sensitivity (FDS) in patients suffering from NP. In each investigation center assessments were performed at the moment of the initial consultation by the same investigator, then updated with complementary exploration results required by the protocol. The chi 2 test and the Fisher test were used for statistical analysis. In this study 224 patients were included. Males were predominant at 63%. Asthma was found in 45% of cases without relevant sex difference. However, FDS, positive in 31% of the patients, was statistically higher in females than in males (42.9% vs. 24.4%). Severe and major symptoms were more frequently found in the female population. Environment and habitat factors did not appear to be relevant. High rates of NP (52.66%) and asthma (43.58%) were found in the family history. Hereditary factors were suggested and lead us to further study the genetic factors potentially involved in this pathology.
Assuntos
Pólipos Nasais/epidemiologia , Asma/epidemiologia , Hipersensibilidade a Drogas/epidemiologia , Feminino , Hipersensibilidade Alimentar/epidemiologia , França/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Pólipos Nasais/diagnóstico , Estudos Prospectivos , Distribuição por SexoRESUMO
The biocompatibility of the bioactive glass-ceramic Ceravital was investigated experimentally both in vivo and in vitro. In the former, ceramic discs were interposed in 30 rat middle ears for periods ranging from 6 weeks to 12 months. In the latter, Ceravital otological prosthesis were placed in human fibroblast culture. Reactions to the biomaterial were assessed by means of scanning electron microscopy (SEM) with chemical analysis facilities (EDAX, WDAX) and light microscopy. The interface reactions were similar in both in vivo and in vitro studies and confirmed the findings of other authors regarding the implants' biocompatibility and bioactivity. The technique of ion etching, however, enabled clear demonstration of this bioactivity on the implant surface, exposed merely to the middle-ear secretions, thus questioning the necessity of placing bone pâté on the implant head at surgery, in order to encourage bioactive bonding with the overlying drum. A clinical trial of Ceravital in 128 patients with an average follow-up period of 2 years is reported. Forty per cent of these patients underwent a type II tympanoplasty, 60 per cent a type III. Though relatively short-term, the results to date have been encouraging: 88 per cent of the implants have been well-tolerated; 70 per cent of the cases have yielded a satisfactory hearing result; and only 3 per cent of the implanted prostheses have been extruded.
Assuntos
Materiais Biocompatíveis , Cerâmica , Teste de Materiais , Prótese Ossicular , Animais , Células Cultivadas , Ensaios Clínicos como Assunto , Ossículos da Orelha/ultraestrutura , Fibroblastos , Humanos , Microscopia Eletrônica de Varredura , RatosRESUMO
A case of malignant carotid body chemodectoma with neighbouring lymph nodes metastases is reported. The case is noteworthy as it was accompanied by another jugulotympanic chemodectoma. There was also hereditary component as four of the patients forebears had been operated for cervical chemodectomas. An ultrastructural study showed the characteristic secretory granules. 32 other cases of tumors of carotid body and jugular glomus with metastases are reviewed.
Assuntos
Tumor do Corpo Carotídeo/patologia , Metástase Linfática/patologia , Paraganglioma Extrassuprarrenal/patologia , Adolescente , Adulto , Tumor do Corpo Carotídeo/genética , Tumor do Corpo Carotídeo/cirurgia , Feminino , Humanos , Microscopia Eletrônica , Paraganglioma Extrassuprarrenal/genética , Paraganglioma Extrassuprarrenal/cirurgiaRESUMO
The authors present statistics of 40 acoustic neuromas operated upon by micro-surgical technique in co-operation with oto-neuro-surgery. As regards clinical picture, all persons presenting with unilateral progressive sensoryneural deafness should be subjected to cochlear vestibular and radiologic examination. They advocated essentially two routes:--translabyrinthine approach for the tumours within the internal auditory meatus, --posterior fossa approach for the other tumours. They reported their results and analysed the major advantages of the microsurgical technique which diminish considerably the risk of this surgery, so that the functional result should be of first importance.
Assuntos
Neuroma/cirurgia , Neoplasias do Sistema Nervoso Periférico/cirurgia , Nervo Vestibulococlear/cirurgia , Adulto , Idoso , Fossa Craniana Posterior/cirurgia , Orelha Interna/cirurgia , Feminino , Humanos , Masculino , Microcirurgia , Pessoa de Meia-Idade , Complicações Pós-OperatóriasRESUMO
Congenital malformations and agenesis of the ear can affect the external and middle ears, while internal ear structures are generally spared. The malformations may be of different degrees but two stages are usually distinguished. Major agenesis involves malformations of the pinna with absence of the canal and severe middle ear lesions, while in minor agenesis the external ear is only slightly affected or is normal, but is associated with malformations of the auditory ossicula and the walls of the tympanic cavity. The difficulty in deciding on therapy and the extreme variability of results from one case to another explains the wide divergence of opinions of different authors. Three factors are of importance to ensure effective treatment : as early as possible detection, determination of suitability for operation by a complete investigation, and language teaching, a major problem in bilateral agenesis, by means of a hearing-aid initially, followed by surgery.
Assuntos
Orelha/anormalidades , Orelha/cirurgia , HumanosRESUMO
The enlarged retro-labyrinthic route described here allows opening of the internal auditory canal, exeresis of tumors localized in the ponto-cerebellous angle and in the internal auditory canal. We used this route for 55 neurinomas of the auditory nerve (7.4% stage I, 23.6% stage II, 45.4% stage III and 23.6% stage IV). Most of the tumors in our series were > 2 cm. There were no post-operative deaths. Risk of fistulization was low, 3.8%. Post-operative meningitis (3.8%) regressed rapidly with treatment. Facial function outcome was equivalent to that obtained with the enlarged trans-labyrinthic route and reported in the literature in series treated via the sub-occipital route (83.6% for grades I and II, 11% for grade III). One patient required hypoglosso-facial anastomosis with a grade IV result at 6 months. Auditive function was preserved at a socially acceptable level in 14.5% of the patients and in 21.8% hearing aids were needed. Selecting a subgroup of 25 patients with good quality hearing prior to surgery (< 30 dB) and a tumor invading less than three-fourths of the internal auditory canal, for all tumor sizes, 28% preserved socially acceptable hearing. To these must be added 20% who had some hearing loss which could be corrected. The modulary mature of the retrolabyrinthic route is easily transposable to the trans-labyrinthic rout. Because of the potential for preserving auditive function this technique should replace the less flexible sub-occipital route.
Assuntos
Neuroma Acústico/cirurgia , Audiometria , Orelha Interna/cirurgia , Eletrofisiologia , Estudos de Avaliação como Assunto , Nervo Facial/fisiopatologia , Seguimentos , Humanos , Imageamento por Ressonância Magnética , Métodos , Complicações Pós-Operatórias , Período Pós-Operatório , Fatores de RiscoRESUMO
We developed a new biomaterial designed to replaced loss of tympanic tissue. This new material has an original collagen-elastin structure which can be used to create an new artificial conjunctive matrix. The concept and the first experimental results are reported.
Assuntos
Materiais Biocompatíveis , Colágeno , Elastina , Timpanoplastia/instrumentação , Animais , Modelos Animais de Doenças , Teste de Materiais , CoelhosRESUMO
We report our experience with a new access route for benign expansive bone tumors of the anterior floor of the skull. From 1991, we used a unique transfrontonasal route, adapted from Raveh's technique for trauma surgery of the anterior floor, to access all tumors in this region. The images presented here show the advantages of this technique: overall vision allows permanent intraoperative control. In addition, the absence functional or esthetic sequelae favor this route for benign tumors.
Assuntos
Craniotomia/métodos , Neoplasias Cranianas/cirurgia , Adolescente , Adulto , Osso Etmoide/cirurgia , Feminino , Seguimentos , Testa/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Osso Nasal/cirurgia , Retalhos CirúrgicosRESUMO
OBJECTIVE: To review patient selection and factors affecting the decision for surgical or non-surgical management of patients with trauma-induced facial nerve palsy. STUDY DESIGN: Retrospective review of 85 consecutive cases occurring over a 6-year period. METHODS: Between 1984 and 1990, 85 cases of facial nerve palsy following trauma were treated. Patient assessment included clinical, audiological, radiological and EMG examinations. Depending on test results, patients were either given medical treatment or underwent total facial nerve decompression surgery. RESULTS: Recovery was achieved in all 33 medically treated patients. Among the 52 surgically-treated patients (61.2%), 47 had immediate facial nerve palsy at admission (90.4%). Onset of facial palsy was delayed in 5 others, including 3 for whom the delay to onset was unknown. Surgical accesses used were the middle fossa and transmastoidal (60%), translabyrinthine (11%), and pure transmastoidal (29%) routes depending on hearing loss, location of fracture line and general patient condition. Lesions were predominantly found in the geniculate ganglion area. A nerve gap was found in only 13.5% of the cases. Two years post-operatively, 92.3% of the patients had grade I-III recovery. No grade V or VI cases were observed. DISCUSSION AND CONCLUSION: The rarity of severe nerve lesions encountered in surgically-treated patients raises the question of better candidate selection for surgery. At present, imaging techniques, particularly radiology, can help to choose the best indication. Immediate total facial palsy associated with a clear-cut fracture going through the Fallopian canal is perhaps the only case requiring surgery. When the delay of onset is unknown, an EMG indicating a total denervation process is the decisive argument.
Assuntos
Paralisia Facial/terapia , Fraturas Ósseas/complicações , Adolescente , Adulto , Idoso , Criança , Paralisia Facial/etiologia , Paralisia Facial/cirurgia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Risco , Resultado do TratamentoRESUMO
UNLABELLED: The purpose of this research was to evaluate long-term results of fractionated radiation therapy (RT) in the treatment of cerebello-pontine angle schwannomas. METHODS: from January 1986 to October 1995, 29 patients with stage III and IV scwhannomas were treated with external fractionated RT. One patient was irradiated on both sides and indication for RT was as follows: a) poor general condition or old age contraindicating surgery, 16 cases; b) hearing preservation in bilateral tumors after contralateral tumor removal, 6 cases; c) partial resection or high risk of recurrence after subsequent surgery for relapse, 5 cases; d) non surgical relapse, 3 cases. Most patients were irradiated with 6 to 10 MV photons. A three- to four-field technique with coplanar static beams and conformal blocks was used. Doses were calculated on a 95 % isodose and were given 5 days a week for a mean total dose of 51 Gy (1.8 Gy/fraction). RESULTS: Median follow-up from RT was 66 months (7 to 120); seven patients died, two with progressive disease, five from non tumoral cause. Two patients underwent total removal after RT (1 stable and 1 growing tumor). On the whole, tumor shrinkage was observed in 13 patients (43.3 %), stable disease in 14 (46.6 %), and tumor progression in three. Hearing was preserved in 4 out of 6 hearing patients (1 class A hearing, 2 class B and 1 class C). No patient experienced CN5 or CN7 neuropathy. CONCLUSION: long-term efficacy or fractionated RT is well documented in this series. Acute and delayed tolerance was excellent. Hearing can be preserved for a long time.