Detalhe da pesquisa
1.
Cellular processing of α-synuclein fibrils results in distinct physiological C-terminal truncations with a major cleavage site at residue Glu 114.
J Biol Chem
; 299(7): 104912, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37307916
2.
Tau Lysine Pseudomethylation Regulates Microtubule Binding and Enhances Prion-like Tau Aggregation.
Int J Mol Sci
; 24(9)2023 May 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37175990
3.
Novel Conformation-Dependent Tau Antibodies Are Modulated by Adjacent Phosphorylation Sites.
Int J Mol Sci
; 24(18)2023 Sep 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37761979
4.
Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human α-synuclein transgenic mice.
Acta Neuropathol
; 143(6): 663-685, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35488930
5.
A multiverse of α-synuclein: investigation of prion strain properties with carboxyl-terminal truncation specific antibodies in animal models.
Acta Neuropathol Commun
; 12(1): 91, 2024 Jun 10.
Artigo
Inglês
| MEDLINE | ID: mdl-38858742
6.
Tau mutation S356T in the three repeat isoform leads to microtubule dysfunction and promotes prion-like seeded aggregation.
Front Neurosci
; 17: 1181804, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37304025
7.
Polymerization of recombinant tau core fragments in vitro and seeding studies in cultured cells.
Front Neurosci
; 17: 1268360, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-38161790
8.
Carboxyl truncation of α-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of α-synuclein pathogenesis.
Acta Neuropathol Commun
; 11(1): 119, 2023 07 23.
Artigo
Inglês
| MEDLINE | ID: mdl-37482615
9.
Reassessment of Neuronal Tau Distribution in Adult Human Brain and Implications for Tau Pathobiology.
Acta Neuropathol Commun
; 10(1): 94, 2022 06 28.
Artigo
Inglês
| MEDLINE | ID: mdl-35765058
10.
Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice.
Commun Biol
; 5(1): 446, 2022 05 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35550593
11.
Tau K321/K353 pseudoacetylation within KXGS motifs regulates tau-microtubule interactions and inhibits aggregation.
Sci Rep
; 11(1): 17069, 2021 08 23.
Artigo
Inglês
| MEDLINE | ID: mdl-34426645
12.
Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer's disease and other tauopathies.
Acta Neuropathol Commun
; 8(1): 88, 2020 06 22.
Artigo
Inglês
| MEDLINE | ID: mdl-32571418