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1.
West Afr J Med ; 40(12 Suppl 1): S43, 2023 Dec 04.
Artigo em Inglês | MEDLINE | ID: mdl-38071506

RESUMO

The authors report a case of ocular myasthenia revealed by a myasthenic crisis after antimalarial treatment with quinine in a 14-year-old girl. The patient's exploration by a chest scan had revealed a thymoma and the test of acetylcholine receptor antibodies was strongly positive. Finally, electromyography revealed a decrement greater than 10% to repetitive nerve stimulation. The interest of this issue lies in the rarity of this observation in Black Africa, where it is often confused with malaria.


Assuntos
Miastenia Gravis , Timoma , Neoplasias do Timo , Feminino , Humanos , Adolescente , Miastenia Gravis/diagnóstico , Miastenia Gravis/tratamento farmacológico , Eletromiografia
2.
Am J Med Genet A ; 182(6): 1316-1320, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-32297714

RESUMO

The aim of this article is to describe the first case of Hutchinson-Gilford Progeria Syndrome (HGPS) in Togo and review all Africans cases. Our patient was a 12.8-year-old Togolese boy followed in our unit till he was 15-year-old for HGPS. He was the only child of non-consanguineous parents. The phenotypic findings were craniofacial dysmorphy, dwarfism, lipodystrophy, diffusely scattered hyperpigmented foci, pyriform thorax, nail dystrophy, decreased joint mobility, and camptodactyly. He had characteristic facies with prominent forehead, prominent eyes, absent ear lobule, thin nasal skin, convex nasal profile, micrognathia, and crowded teeth. Radiologicals findings were bilateral coxa valga, pyriform thorax, and acro-osteolysis. We sequenced the entire coding region of LMNA gene, and mutation analysis revealed a heterozygous mutation c.1824C>T (p.Gly608Gly). Our patient is therefore the fifth African and the fourth with classical mutation, first of Western Africa, and second of (sub-Saharan) African black race. The recurrence of HGPS is low like the cause is neomutation or germinal mosaicism.


Assuntos
Anormalidades Craniofaciais/genética , Predisposição Genética para Doença , Lamina Tipo A/genética , Progéria/genética , Adolescente , Criança , Anormalidades Craniofaciais/patologia , Nanismo/genética , Nanismo/patologia , Humanos , Lipodistrofia/genética , Lipodistrofia/patologia , Masculino , Progéria/patologia
3.
BMC Geriatr ; 20(1): 507, 2020 11 26.
Artigo em Inglês | MEDLINE | ID: mdl-33243161

RESUMO

BACKGROUND: Assessing hospital mortality and its predictors is important as some of these can be prevented through appropriate interventions. Few studies have reported hospital mortality data among older adults in sub-Saharan Africa. The objective of this study was to assess the mortality and associated factors among hospitalized older adults in Togo. METHODS: We conducted a prospective cohort study from February 2018 to September 2019 among patients ≥50 years admitted in medical and surgical services of six hospitals in Togo. Data were recorded during hospitalization and through telephone follow-up survey within 90 days after admission. The main outcome was all-cause mortality at 3 months. Survival curves were estimated using the Kaplan-Meier method and Cox regression analyses were performed to assess predictors of mortality. RESULTS: The median age of the 650 older adults included in the study period was 61 years, IQR: [55-70] and at least one comorbidity was identified in 59.7% of them. The all-cause mortality rate of 17.2% (95%CI: 14.4-20.4) and the majority of death (93.7%) occurred in hospital. Overall survival rate was 85.5 and 82.8% after 30 and 90 days of follow-up, respectively. Factors associated with 3-month mortality were the hospital level in the health pyramid, hospitalization service, length of stay, functional impairment, depression and malignant diseases. CONCLUSION: Togolese health system needs to adjust its response to an aging population in order to provide the most effective care.


Assuntos
Hospitalização , Mortalidade , África Subsaariana , Idoso , Feminino , Mortalidade Hospitalar , Humanos , Masculino , Estudos Prospectivos , Fatores de Risco , Togo/epidemiologia
4.
J Public Health Afr ; 14(5): 2301, 2023 Apr 30.
Artigo em Inglês | MEDLINE | ID: mdl-37441118

RESUMO

Objectives: To assess urinary sodium/potassium intake and identify its links with global cardiovascular risk (GCVR) according to the WHOPEN approach to WHO/ISH (International High Blood Pressure Society). Methods: It was a cross-sectional and analytical study that took place from July 6, 2020, to September 17, 2021, in Togo, in the Aneho, Notse and Dapaong localities. It focused on 400 adults selected by sampling. The analysis of two urine samples was done. Cardiovascular risk scores were determined from specific graphs that take into account age, gender, systolic blood pressure, diabetes status, and smoking behavior. Results: Among the 400 respondents, 49% lived in rural areas. The average age was 41 (30; 51) years. The average sodium and potassium intakes were respectively 3.2 g (1.04-5.99) or 7.95 g of salt and 1.4 g (1.89-5.62) per day. The risk of excessive sodium intake was 2.39 times higher in urban areas than in rural ones (P=0.049). Residing in rural areas was associated with high potassium intakes compared to urban ones [OR=3,2 IC (1.89-5.62)]. Thirteen percent (13%) of respondents were likely to develop at least a deadly or non-deadly cardiovascular disease in the next 10 years 'time, of whom 5% present a high risk. Excessive sodium intake increases by 2.10 times the risk of a deadly cardiovascular disease occurrence. Conclusions: Sodium intakes are high while potassium intakes are low with a subsequent GCVR in the three cities. Sodium intakes were associated with GCVR. It is necessary to take steps to reduce excessive sodium intake and improve potassium intake.

5.
J Neurol Sci ; 434: 120119, 2022 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-34982975

RESUMO

PURPOSE: Neurology is one of Africa's central and noble specialties due to the frequency of its related diseases. Through this study we: -1-described the status of neurologists in Africa in terms of numbers,-2-listed the reasons and discussed how to increase their number, and how to get the most benefit of them in healthcare coverage. METHODS: The distribution and number of neurologists in the African continent was acquired from many participants in different African countries using a survey sent between March 2020 and August 2020 by email. Further, data from the World health organization on the number of neurologists was added for the countries, from which we didn't receive answers by the survey. RESULTS: Surveys' answers were received from representatives of 50 (92%) of the 54 African nations. Authors suggest a ranking into four levels according to the number of neurologists per nation. Level A [more than 201 neurologists per country] included 2 nations. Level B [31 to 200 neurologists per country] included six nations. Level C [1 to 30 neurologists per country] including the majority of African countries (36 nations). Level D includes 10 nations without any neurologists. CONCLUSION: The need for reliable and competent neurologists with a sufficient number is considered as a crucial element to enhance the care of neurological diseases in Africa. For this, all African countries should establish new centers of excellence in neurology, by developing good south-south collaboration with supports from governmental and non-governmental institutions.


Assuntos
Doenças do Sistema Nervoso , Neurologia , África/epidemiologia , População Negra , Países em Desenvolvimento , Humanos , Neurologistas
6.
J Neurosci Rural Pract ; 13(3): 541-545, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-35946029

RESUMO

Introduction Neuromyelitis optica spectrum disorders (NMOSD) would disproportionately affect blacks within mixed populations. However, they are rarely reported in black African. The objective of this work was to report the experience of Togo, a West African country in terms of NMOSD. Methods This is a series of six cases diagnosed between 2015 and 2020 in the only three neurology departments in Togo. The diagnosis of NMOSD was made according to the criteria of the International Panel for NMO Diagnosis (2015) and the patients had a minimum clinical follow-up of 6 months after the diagnosis. The search for anti-aquaporin 4 (AQP4) antibodies was performed by immunofluorescence on transfected cells. Results The mean age was 25.33 years and the sex ratio female/male was 5/1. The average time between the first attack and the diagnosis was 122.83 days. Clinically, there was isolated medullary involvement (2/6), simultaneous opticomedullary involvement (3/6), and area postrema syndrome (1/6). Five patients were anti-AQP4 positive. All six patients had extensive longitudinal myelitis. At 6 months of follow-up, there was one case of death and one case of blindness. Conclusion The rarity of NMOSD cases in Togo could be linked to an underestimation. To better characterize the NMOSDs of the black African population, multicenter and multidisciplinary studies are necessary.

7.
Int J Stroke ; 16(1): 93-99, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-32026763

RESUMO

Africa is the world's most genetically diverse, second largest, and second most populous continent, with over one billion people distributed across 54 countries. With a 23% lifetime risk of stroke, Africa has some of the highest rates of stroke worldwide and many occur in the prime of life with huge economic losses and grave implications for the individual, family, and the society in terms of mental capital, productivity, and socioeconomic progress. Tackling the escalating burden of stroke in Africa requires prioritized, multipronged, and inter-sectoral strategies tailored to the unique African epidemiological, cultural, socioeconomic, and lifestyle landscape. The African Stroke Organization (ASO) is a new pan-African coalition that brings together stroke researchers, clinicians, and other health-care professionals with participation of national and regional stroke societies and stroke support organizations. With a vision to reduce the rapidly increasing burden of stroke in Africa, the ASO has a four-pronged focus on (1) research, (2) capacity building, (3) development of stroke services, and (4) collaboration with all stakeholders. This will be delivered through advocacy, awareness, and empowerment initiatives to bring about people-focused changes in policy, clinical practice, and public education. In the spirit of the African philosophy of Ubuntu "I am because we are," the ASO will harness the power of diversity, inclusiveness, togetherness, and team work to build a strong, enduring, and impactful platform for tackling stroke in Africa.


Assuntos
Acidente Vascular Cerebral , África/epidemiologia , Fortalecimento Institucional , Humanos , Organizações , Acidente Vascular Cerebral/epidemiologia , Acidente Vascular Cerebral/terapia
8.
Sante ; 2010 Aug 04.
Artigo em Francês | MEDLINE | ID: mdl-20682484

RESUMO

The financial crisis that affected the healthcare systems of most developing countries in the 1980s, the ensuing need to control hospital costs, the partial disengagement of States, and the resort to policies based on cost recovery -- all these led to the restructuring of hospital systems in Africa, in accordance with the Bamako initiative, adopted by the WHO regional committee in September 1987. This restructuring required populations to pay much of the cost of their health care. In practice, however, the major obstacle to this policy of cost recovery remains poverty. Twenty years after the adoption of this initiative, we sought to evaluate the cost of hospitalisation for cerebral stroke in Togo, where there is no national health insurance programme, and to propose strategies to improve its management. This prospective study was conducted in the neurology department of the University Hospital of Lomé over a period of 12 months, from 1 January to 31 December 2005 and included 412 consecutive patients with a confirmed diagnosis according to WHO criteria and cerebral computed tomography (CT) results. This department has 30 beds in rooms categorized according to their cost to the patients: EUR 27.30 for a superior single room, EUR 18.20 for the first category standard room, EUR 13.7 euros for the second, and EUR 8.20 for the third. Patients or their family could choose their room category. Of the 412 patients included in our study, 248 (60.2%) had an ischaemic stroke (IS) and 164 (39.8%) a haemorrhagic stroke (HS). The average length of stay was 17.4 +/- 10.4 days (range: 3 to 41 days), 10.17 days (range: 3 to 24) for IS and 26.7 (range: 13 to 41) for HS. In all, 124 (30%) patients produced insurance certificates, and 288 (70%) paid directly; among the latter 152 (36.9%) patients paid their own expenses, while relatives paid for 65 (63.10%). Housewives accounted for 136 (33%) patients, 96 (23%) retired and 180 (20.4%) civil servants. No one chose the superior quality private room; 256 (62%) patients used category 3 rooms, 68 (27.2%) of them housewives and 44 (17.2%) retired. The total cost averaged EUR 679.6 +/- 297.90, almost 19 times higher than the minimum monthly salary of civil servants in Togo (EUR 36.30). The total for IS was EUR 428.80 +/- 188.9 and for HS, EUR 935.6 +/- 36.50. The average person in Togo spends EUR 3.99 per person per year on health, while a stroke patient hospitalized in Lome spends an average of 170 times more in only 17.4 days. Accordingly, most of the Togolese cannot access specialized neurology care for a stroke. Drug expenses accounted for the highest portion of the cost, in part because patients are obliged to buy retail pharmaceutical products that could have been provided to them at the hospital. Use of generic drugs could reduce this cost. Length of stay and tests could be reduced by setting time limits for procedures and setting up rehabilitation facilities.

9.
Sante ; 20(2): 93-7, 2010.
Artigo em Francês | MEDLINE | ID: mdl-20682482

RESUMO

Epilepsy, the most common serious neurological condition, is one of the most widespread non-transmissible diseases in the world. In developing countries, about 90% of those with epilepsy do not receive appropriate treatment; this treatment gap, very high compared with other chronic diseases, helps to explain the marginalisation and poor living conditions of these people. Reducing this treatment gap and the burden that epilepsy represents is a difficult task and the obstacles are numerous. The cultural attitudes, the absence of priority for this disease, the weak health infrastructure and the insufficient supply of anti-epileptics are just some of the factors that prevent adequate treatment. The extent of this problem led WHO and the International League against Epilepsy to launch an international campaign in June 1997 to bring epilepsy "out from the shadows". We sought to evaluate a strategy of community-based care for epilepsy in the six pilot districts. This strategy consisted in reducing the treatment gap in six local primary care units (PCUs) and then spreading the programme to surrounding PCUs, the entire district and then the entire region. This prospective evaluation study, which took place from May 2008 to July 2009, applied many strategies. WHO/AFRO made available funding of USD 3500 a year. A training meeting was held for PCU staff and community health agents, and numerous meetings from May 2007 through March 2008 aimed to increase awareness and motivation. The National Program for Mental Health (NPMH) ensured the availability of a permanent supply of anti-epileptics. Monitoring with supervision of activities and evaluation were conducted during and at the end of the process by the members of the Lomé Hospital neurology team and the management team of every district. Community-based management of 816 people with epilepsy over a period of 15 months was assessed internally. The planned strategies were conducted. The sex ratio (M/W) was 1.10. Treatment adhesion ranged from 96% to 99%. Mortality was 9%. The treatment gap in the PCUs, which varied from 98% to 94% in May 2008 fell by July 2009, ranging from only 40% to 25%. The "good practice" of accepting and treating patients with epilepsy in these areas where traditional culture excludes them from the community demanded the local acceptance of responsibility -- both medical and psychosocial. The reduction in epilepsy attacks and the integration of 2 or 3 patients in a community sufficed to bring other people with epilepsy out from the shadows. These successes show that in developing countries, it is possible to improve the health of different populations when these projects are integrated into primary health care. Positive results, and specifically a treatment gap below 50%, were obtained in all six PCUs. These results, acquired after months of activity, contributed to decrease the stigmatisation of epilepsy. Maintaining this reduction in the treatment gap requires continuation of the struggle against epilepsy and permanent improvement of primary health care. The often unplanned moves of staff and the reluctance of district and regional health managers to allocate resources to the project to perpetuate the programme constitute major difficulties. It appears urgent to adopt an active policy for providing care of patients with epilepsy in Africa in order to increase their lifespan.


Assuntos
Epilepsia/terapia , Atenção Primária à Saúde/normas , Serviços de Saúde Comunitária/organização & administração , Agentes Comunitários de Saúde/educação , Atenção à Saúde/normas , Países em Desenvolvimento , Epilepsia/epidemiologia , Humanos , Projetos Piloto , Togo/epidemiologia
10.
J Public Health Afr ; 11(1): 1302, 2020 Apr 29.
Artigo em Inglês | MEDLINE | ID: mdl-33209236

RESUMO

The number of older adults is increasing worldwide, including in sub-Saharan Africa (SSA). However, there is a paucity of data on the overall health status of older adults living in SSA. To assess the prevalence and factors associated with poor Self-Rated Health (SRH) among community-dwelling older adults in Lomé, Togo, we conducted a cross-sectional study from January to June 2019 in Lomé among community-dwelling older adults aged 50 years and older. A 30- minute questionnaire was used to collect socio-demographic characteristics, medical history, patterns of medication use and use of herbal products and dietary supplements during a face-to-face interview. SRH was assessed using a single item: Overall, you would say that your health is… (1) excellent, (2) very good, (3) good, (4) fair and (5) poor with response fair or poor defining poor SRH. A total of 344 respondents with median age 63 years, (IQR: 55-72) were enrolled in the study. Women represented 57.6% of the sample. Overall prevalence of poor SRH was 56.4% (95%CI: 51.0-61.9) and was the highest among females (62.6% vs 47.9%; P=0.007) and participants ³60 years (61.5% vs 51.1%; P=0.021). Female sex, aged ≥60 years, osteoarthritis, hospitalization within the 12 months preceding the survey, polypharmacy, and the use of herbal products were factors associated with poor SRH (P<0.05). More than half of community- dwelling older adults had poor SRH in Lomé. Further studies are needed to guide policymakers in their efforts to design and implement meaningful policies to improve older adults health conditions.

11.
Curr Gerontol Geriatr Res ; 2020: 4346035, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32351556

RESUMO

BACKGROUND: In the sub-Saharan African, region of the world with a fast growing aging population and where the use of herbal products is very common, there is a paucity of data on medication consumption patterns among elderly people. The objective of this study was to assess the prevalence of polypharmacy and its associated factors among community-dwelling elderly in Lomé, Togo, in 2017. METHODS: A cross-sectional study was conducted from March to June 2017 in Lomé, Togo among people aged 60 years and older. The Respondent Driven Sampling method was used to recruit participants. Data on socio-demographic characteristics and medication consumption patterns, including the use of medicinal plants and dietary supplements, were collected using a standardized questionnaire during a face-to-face interview at participants' home. Descriptive and binary logistic regression analyses were performed. RESULTS: A total of 370 participants with median age 65 years, (IQR: 62-71) were enrolled in the study. Almost three elderly in five (57.6%) were multimorbid (had two or more chronic diseases). Conventional drugs (78.4%), medicinal plants (14.3%) and other dietary supplements (9.5%) were used by participants. The prevalence of polypharmacy was 22.7% (95% CI: 18.5-27.3%). Concurrent use of conventional drugs and medicinal plants or other dietary supplements was observed among 17.0% of participants and 67.3% reported self-medication. Multimorbidity (aOR = 4.55; 95% CI: [2.42-8.54]) and female sex (aOR = 1.86; 95% CI: [1.00-3.47]) were associated with polypharmacy. CONCLUSION: One elderly in five uses five or more medications in Togo. Further studies are needed to assess drug-drug interactions and herb-drug interactions among this population.

12.
Artigo em Inglês | AIM | ID: biblio-1435821

RESUMO

Objectives. To assess urinary sodium/potassium intake and identify its links with global cardiovascular risk (RCVG) according to the WHOPEN approach to WHO/ISH (International High Blood Pressure Society). Methods. It was a cross-sectional and analytical study that took place from July 6, 2020, to September 17, 2021, in Togo, in the Aneho, Notse and Dapaong localities. It focused on 400 adults selected by sampling. The analysis of two urine samples was done. Cardiovascular risk scores were determined from specific graphs that take into account age, gender, systolic blood pressure, diabetes status and smoking behavior. Results. Among the 400 respondents, 49% lived in rural areas. The average age was 41 (30; 51) years. The average sodium and potassium intakes were respectively 3.2 g (1.04-5.99) or 7.95 g of salt and 1.4 g (1.89-5.62) per day. The risk of excessive sodium intake was 2.39 times higher in urban areas than in rural ones (p=0.049). Residing in rural areas was associated with high potassium intakes compared to urban ones (OR=3,2 IC [1.89-5.62]). Thirteen percent (13%) of respondents were likely to develop at least a deadly or non-deadly cardiovascular disease in the next 10 years 'time, of whom 5% present a high risk. Excessive sodium intake increases by 2.10 times the risk of a deadly cardiovascular disease occurrence. Conclusions. Sodium intakes are high while potassium intakes are low with a subsequent global cardiovascular risk (GCVR) in the three cities. Sodium intakes were associated with VCVR. It is necessary to take steps to reduce excessive sodium intake and improve potassium intake.


Assuntos
Potássio , Sódio , Doenças Cardiovasculares , Hipertensão
13.
J Neurosci Rural Pract ; 6(2): 221-4, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25883484

RESUMO

INTRODUCTION: The extent of neuromeningeal cryptococcosis (NMC) has increased since the advent of HIV/AIDS. It has non-specific clinical signs but marked by high mortality. OBJECTIVE: To analyze the characteristics of the NMC in sub-Saharan Africa. MATERIALS AND METHODS: We have conducted a literature reviewed on the NMC in sub-Saharan Africa from the publications available on the basis of national and international data with keywords such as "Cryptococcus, Epidemiology, Symptoms, Outcomes and Mortality" and their equivalent in French in July 2011. All publications from 1990 to 2010 with 202 references were analyzed. The following results are the means of different studied variables. RESULTS: We selected in final 43 publications dealing with the NMC which 24 involved 17 countries in Africa. The average age was 36 years old. The average prevalence was 3.41% and the average incidence was 10.48% (range 6.90% to 12%). The most common signs were fever (75%), headaches (62.50%) and impaired consciousness. Meningeal signs were present in 49% of cases. The mean CD4 count was 44.8cells/mm(3). The India ink and latex agglutination tests were the most sensitive. The average time before the consultation and the hospital stay was almost identical to 27.71 days. The average death rate was 45.90%. Fluconazole has been the most commonly used molecule. CONCLUSION: The epidemiological indicators of NMC varied more depending on the region of sub-Saharan Africa. Early and effective taking care of patients to reduce diagnostic delay and heavy mortality remains the challenges.

14.
Sante ; 14(2): 109-14, 2004.
Artigo em Francês | MEDLINE | ID: mdl-15454370

RESUMO

For many years the cost of health care in sub-Saharan Africa was largely covered by the State. But in September 1987, in view of the economical problems those countries had to face, the WHO regional committee adopted the "Bainako's Initiative" resolution. This meant that from then on everybody was to pay for their health expenses. The purpose of this prospective study which was conducted from March 1, 1996 to February 28, 1999 among 316 patients was to assess hospitalization charges incurred for patients in the Neurology Department of Lomé Teaching Hospital with a view to improve the quality of the services provided and the accessibility of care. A questionnaire was used and every expense relating to the hospitalization of each patient was recorded on a daily basis. The average cost is 389,586 (48,485 FCFA for an average stay of 19.7 (2.5 days. This average cost is 19 times the minimal monthly salary of a state employee. It can be broken down as follows: Accommodation costs represent 52%, medical acts and tests 20.3% while drug costs amount to 21.2% and accompanist expenses represent 6.5%. The average cost of HIV-infected patients is 635,017 (190,624 FCFA for an average stay of 57 (12.9 days. The average cost of HIV-negative patients is 257,354 (12,837 FCFA for an average stay of 24.4 (1.8 days. To improve the quality of the services and the accessibility of care, it is necessary to prescribe and make drugs available in their generic form. After a few days in hospital, some disabling diseases as strokes, myelopathy and myopathy should be treated at home to reduce the length of stay in hospital or in cheaper places such as prolonged accommodation centres.


Assuntos
Custos de Cuidados de Saúde/estatística & dados numéricos , Preços Hospitalares/estatística & dados numéricos , Adulto , Feminino , Pesquisas sobre Atenção à Saúde , Acessibilidade aos Serviços de Saúde , Hospitalização/economia , Humanos , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Qualidade da Assistência à Saúde , Togo
15.
Tunis Med ; 80(1): 33-6, 2002 Jan.
Artigo em Francês | MEDLINE | ID: mdl-12071042

RESUMO

To ascertain the aetiology, of non traumatic paraplegia retrospective survey, concerning 2396 patients hospitalised from January 1st 1995 to December 31st 1999, was done. Two hundred forty three cases were founded after investigation. The frequency of non traumatic paraplegia was 10.14%. Peripheral motor neuron's causes were 48.97% (119 cases). In this group, tropical neuromyelopathies were the commonest 65.54% (78 cases) while Guillain Barre syndrome was 3.36% (4 cases). Bones, epidural et meningeal (envelope) causes were 38.68% (94 cases). In this group, tuberculosis was 17 cases, tumour 36 cases. Central motor neuron causes were 9.46% (23 cases) with HIV myelitis 13 cases, tumour 3 cases, degenerative conditions 6 cases. It is concluded that the major causes of non traumatic paraplegia in Lome are similar to that reported from sub sahara countries with tropical neuromyelopathies, tumours, tuberculosis and HIV myelitis.


Assuntos
Paraplegia/etiologia , Doenças do Sistema Nervoso Periférico/complicações , Adolescente , Adulto , Idoso , Criança , Feminino , Síndrome de Guillain-Barré/complicações , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Doença dos Neurônios Motores/complicações , Paraplegia/epidemiologia , Estudos Retrospectivos , Tuberculose/complicações , Tunísia/epidemiologia
16.
Afr J Paediatr Surg ; 11(2): 162-5, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24841019

RESUMO

BACKGROUND: The aim of this study was to evaluate pain management in paediatric surgery at Sylvanus Olympio University Teaching Hospital, Lome. PATIENTS AND METHODS: A prospective descriptive study was conducted in the Department of Anaesthesiology and Intensive Care at Sylvanus Olympio teaching hospital from 1 January to 30 June 2012. Data collected include: demography, type of surgery, American Society of Anaesthesiologists (ASA) classification, anaesthetic protocol, analgesia technique, post-operative complications and cost of analgesia. RESULTS: The study includes 106 post-operative children. Abdominal surgery was performed in 41.5% and orthopaedic surgery in 31.1%. A total of 75% of patients were classified ASA 1. General anaesthesia (GA) was performed in 88%. Anaesthetists supervised post-operative care in 21.7% cases. Multimodal analgesia was used in every case and 12% of patients received a regional block. The most frequently unwanted effects of analgesics used were nausea and/or vomiting in 12.3%. At H24, child under 7 years have more pain assessment than those from 7 to 15 years (46% vs 24%) and this difference was statistically significant (chi-square = 4.7598; P = 0.0291 < 0.05). The average cost of peri-operative analgesia under loco regional analgesia (LRA) versus GA during the first 48 h post-operative was US $23 versus $46. CONCLUSION: Our study showed that post-operative pain management in paediatric surgery is often not well controlled and paediatric loco regional analgesia technique is under practiced in sub Saharan Africa.


Assuntos
Manejo da Dor/métodos , Dor Pós-Operatória/diagnóstico , Dor Pós-Operatória/terapia , Procedimentos Cirúrgicos Operatórios/efeitos adversos , Adolescente , Analgésicos Opioides/uso terapêutico , Distribuição de Qui-Quadrado , Criança , Pré-Escolar , Estudos de Coortes , Países em Desenvolvimento , Feminino , Hospitais de Ensino , Hospitais Universitários , Humanos , Lactente , Masculino , Bloqueio Nervoso/métodos , Medição da Dor , Dor Pós-Operatória/epidemiologia , Pediatria/métodos , Estudos Prospectivos , Medição de Risco , Índice de Gravidade de Doença , Procedimentos Cirúrgicos Operatórios/métodos , Togo , Resultado do Tratamento
17.
Afr. j. neurol. sci. (Online) ; 34(1): 17-25, 2015. tab
Artigo em Francês | AIM | ID: biblio-1257438

RESUMO

Description La sténose du canal lombaire est une affection rachidienne fréquente. A Parakou, sa prise en charge neurochirurgicale est possible malgré notre modeste plateau technique.Objectif Rapporter les résultats chirurgicaux et fonctionnels des sténoses du canal lombaire opérées dans une unité de neurochirurgie au Bénin.Méthodes Il s'est agi d'une étude rétrospective et descriptive basée sur examen de dossiers. Elle a inclu tous les patients opérés pour une sténose du canal lombaire entre Janvier 2008 et Mars 2013 au Centre Hospitalier Universitaire et Départemental du Borgou/Alibori (CHUD-B/A) du Bénin. Les renseignements cliniques et l'imagerie ont permis de poser le diagnostic puis les indications opératoires. Les variables étudiées étaient les données socio démographiques, les signes cliniques, l'imagerie et l'évolution post opératoire.Résultats Durant la période de l'étude, 178 cas de sténose du canal lombaire opéré ont été retenus. Ces patients se répartissaient en 97 hommes (54,5%) et 81 femmes (45,5%). L'âge moyen des patients était de 52,36 ± 10,94 ans. La claudication neurogène (92,7%), Les radiculalgies (93, 8%) et les troubles mictionnels (59,6%) étaient les principaux signes cliniques. Leur durée moyenne d'évolution était de 3,55±2,46 ans. Le scanner lombaire a contribué au diagnostic pour 147 patients (82,6%). Les suites opératoires était simples (88,8%) et les résultats fonctionnels étaient excellents ou bons dans 84,2% des cas. Les principales complications étaient les brèches durales (5,6%) et les suppurations pariétales (3,9%). La létalité était de 1,1% (n=2).Conclusion La chirurgie de la sténose du canal lombaire est réalisable à Parakou. Les résultats post opératoires et fonctionnels sont conformes à la littérature


Assuntos
Laminectomia
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