Detalhe da pesquisa
1.
Chemical control of structure and guest uptake by a conformationally mobile porous material.
Nature
; 565(7738): 213-217, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30626943
2.
The Synthesis and Reactivity of Naphthoquinonynes.
Angew Chem Int Ed Engl
; 63(18): e202400188, 2024 Apr 24.
Artigo
Inglês
| MEDLINE | ID: mdl-38445547
3.
AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis.
Proc Natl Acad Sci U S A
; 116(4): 1414-1419, 2019 01 22.
Artigo
Inglês
| MEDLINE | ID: mdl-30617067
4.
Machine-Learning Prediction of Metal-Organic Framework Guest Accessibility from Linker and Metal Chemistry.
Angew Chem Int Ed Engl
; 61(9): e202114573, 2022 Feb 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34878706
5.
Amino Acid Residues Determine the Response of Flexible Metal-Organic Frameworks to Guests.
J Am Chem Soc
; 142(35): 14903-14913, 2020 09 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32786807
6.
New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors.
Biochem J
; 475(15): 2435-2455, 2018 08 14.
Artigo
Inglês
| MEDLINE | ID: mdl-29934490
7.
New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors.
Biochem J
; 475(15): 2417-2433, 2018 08 14.
Artigo
Inglês
| MEDLINE | ID: mdl-29934491
8.
α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy.
Neurobiol Dis
; 118: 40-54, 2018 10.
Artigo
Inglês
| MEDLINE | ID: mdl-29940336
9.
Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1.
Proc Natl Acad Sci U S A
; 112(3): 755-60, 2015 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-25564664
10.
Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.
Proc Natl Acad Sci U S A
; 109(21): 8298-303, 2012 May 22.
Artigo
Inglês
| MEDLINE | ID: mdl-22566611
11.
Abacavir forms novel cross-linking abacavir protein adducts in patients.
Chem Res Toxicol
; 27(4): 524-35, 2014 Apr 21.
Artigo
Inglês
| MEDLINE | ID: mdl-24571427
12.
Carbon monoxide poisoning is prevented by the energy costs of conformational changes in gas-binding haemproteins.
Proc Natl Acad Sci U S A
; 108(38): 15780-5, 2011 Sep 20.
Artigo
Inglês
| MEDLINE | ID: mdl-21900609
13.
Guest-adaptable and water-stable peptide-based porous materials by imidazolate side chain control.
Angew Chem Int Ed Engl
; 53(1): 193-8, 2014 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-24302659
14.
Design, synthesis and modelling of photoreactive chemical probes for investigating target engagement of plasmepsin IX and X in Plasmodium falciparum.
RSC Chem Biol
; 5(1): 19-29, 2024 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38179191
15.
Antitubercular pharmacodynamics of phenothiazines.
J Antimicrob Chemother
; 68(4): 869-80, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23228936
16.
Snakebite drug discovery: high-throughput screening to identify novel snake venom metalloproteinase toxin inhibitors.
Front Pharmacol
; 14: 1328950, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-38273820
17.
Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform.
Front Pharmacol
; 14: 1331224, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-38273832
18.
Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis.
ACS Infect Dis
; 9(2): 221-238, 2023 02 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36606559
19.
HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex.
Antimicrob Agents Chemother
; 56(7): 3739-47, 2012 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-22547613
20.
Targeting the Ubiquinol-Reduction (Qi) Site of the Mitochondrial Cytochrome bc1 Complex for the Development of Next Generation Quinolone Antimalarials.
Biology (Basel)
; 11(8)2022 Jul 25.
Artigo
Inglês
| MEDLINE | ID: mdl-35892964