Detalhe da pesquisa
1.
ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.
Hum Mol Genet
; 30(13): 1175-1187, 2021 06 17.
Artigo
Inglês
| MEDLINE | ID: mdl-33601422
2.
RUES2 hESCs exhibit MGE-biased neuronal differentiation and muHTT-dependent defective specification hinting at SP1.
Neurobiol Dis
; 146: 105140, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33065279
3.
PD-1 expression is upregulated on adapted T cells in experimental autoimmune encephalomyelitis but is not required to maintain a hyporesponsive state.
Eur J Immunol
; 49(1): 112-120, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30485411
4.
Differentiation of human telencephalic progenitor cells into MSNs by inducible expression of Gsx2 and Ebf1.
Proc Natl Acad Sci U S A
; 114(7): E1234-E1242, 2017 02 14.
Artigo
Inglês
| MEDLINE | ID: mdl-28137879
5.
Loss of NGF-TrkA signaling from the CNS is not sufficient to induce cognitive impairments in young adult or intermediate-aged mice.
J Neurosci
; 32(43): 14885-98, 2012 Oct 24.
Artigo
Inglês
| MEDLINE | ID: mdl-23100411
6.
hESC-derived striatal progenitors grafted into a Huntington's disease rat model support long-term functional motor recovery by differentiating, self-organizing and connecting into the lesioned striatum.
Stem Cell Res Ther
; 14(1): 189, 2023 07 28.
Artigo
Inglês
| MEDLINE | ID: mdl-37507794
7.
In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution.
Cell Rep Methods
; 2(12): 100367, 2022 12 19.
Artigo
Inglês
| MEDLINE | ID: mdl-36590694
8.
Modeling human telencephalic development and autism-associated SHANK3 deficiency using organoids generated from single neural rosettes.
Nat Commun
; 13(1): 5688, 2022 10 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36202854
9.
hiPSCs for predictive modelling of neurodegenerative diseases: dreaming the possible.
Nat Rev Neurol
; 17(6): 381-392, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33658662
10.
The coding and long noncoding single-cell atlas of the developing human fetal striatum.
Science
; 372(6542)2021 05 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33958447
11.
A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2.
Stem Cell Res
; 49: 102016, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33039807
12.
Stem Cell-Derived Human Striatal Progenitors Innervate Striatal Targets and Alleviate Sensorimotor Deficit in a Rat Model of Huntington Disease.
Stem Cell Reports
; 14(5): 876-891, 2020 05 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32302555
13.
Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease.
J Clin Invest
; 129(6): 2390-2403, 2019 05 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31063986
14.
LPS-matured CD11c+ bone marrow-derived dendritic cells can initiate autoimmune pathology with minimal injection site inflammation.
Lab Anim
; 51(3): 292-300, 2017 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-27488372
15.
Prevention of spontaneous mammary adenocarcinoma in HER-2/neu transgenic mice by foreign DNA.
FASEB J
; 16(13): 1749-54, 2002 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-12409317
16.
1,25-Dihydroxyvitamin D3-Conditioned CD11c+ Dendritic Cells are Effective Initiators of CNS Autoimmune Disease.
Front Immunol
; 6: 575, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26635791
17.
BDNF-TrkB signaling in striatopallidal neurons controls inhibition of locomotor behavior.
Nat Commun
; 4: 2031, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23774276
18.
Targeting Plk1 to chromosome arms and regulating chromosome compaction by the PICH ATPase.
Cell Cycle
; 7(10): 1480-9, 2008 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-18418076
19.
A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.
J Biol Chem
; 282(24): 17330-4, 2007 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17478428
20.
Antitumor activity of the TLR-5 ligand flagellin in mouse models of cancer.
J Immunol
; 176(11): 6624-30, 2006 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-16709820