Detalhe da pesquisa
1.
Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults.
Proc Natl Acad Sci U S A
; 115(14): 3686-3691, 2018 04 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29555771
2.
Profiling of Short-Tandem-Repeat Disease Alleles in 12,632 Human Whole Genomes.
Am J Hum Genet
; 101(5): 700-715, 2017 Nov 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29100084
3.
Fast and accurate HLA typing from short-read next-generation sequence data with xHLA.
Proc Natl Acad Sci U S A
; 114(30): 8059-8064, 2017 07 25.
Artigo
Inglês
| MEDLINE | ID: mdl-28674023
4.
Deep sequencing of 10,000 human genomes.
Proc Natl Acad Sci U S A
; 113(42): 11901-11906, 2016 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-27702888
5.
Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.
Nat Genet
; 32(2): 245-53, 2002 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-12219087
6.
The forkhead transcription factor Foxo1 regulates adipocyte differentiation.
Dev Cell
; 4(1): 119-29, 2003 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-12530968
7.
Tuning a three-component reaction for trapping kinase substrate complexes.
J Am Chem Soc
; 130(51): 17568-74, 2008 Dec 24.
Artigo
Inglês
| MEDLINE | ID: mdl-19053485
8.
A small molecule-kinase interaction map for clinical kinase inhibitors.
Nat Biotechnol
; 23(3): 329-36, 2005 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-15711537
9.
Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680.
Cancer Res
; 66(2): 1007-14, 2006 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-16424036
10.
The human noncoding genome defined by genetic diversity.
Nat Genet
; 50(3): 333-337, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29483654
11.
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth.
J Clin Invest
; 110(12): 1839-47, 2002 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-12488434
12.
Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites.
Nat Genet
; 49(4): 568-578, 2017 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-28263315
13.
Company profile: Aviir, Inc.
Pharmacogenomics
; 14(3): 245-8, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23394387
14.
Analytical performance validation of a coronary heart disease risk assessment multi-analyte proteomic test.
Expert Opin Med Diagn
; 7(2): 127-36, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23530883
15.
Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases.
Proc Natl Acad Sci U S A
; 102(31): 11011-6, 2005 Aug 02.
Artigo
Inglês
| MEDLINE | ID: mdl-16046538
16.
Identification and characterization of mouse SSX genes: a multigene family on the X chromosome with restricted cancer/testis expression.
Genomics
; 82(6): 628-36, 2003 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-14611804
17.
Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification.
Proc Natl Acad Sci U S A
; 101(9): 2975-80, 2004 Mar 02.
Artigo
Inglês
| MEDLINE | ID: mdl-14978268
18.
Analysis of the regulation of the A33 antigen gene reveals intestine-specific mechanisms of gene expression.
J Biol Chem
; 277(37): 34531-9, 2002 Sep 13.
Artigo
Inglês
| MEDLINE | ID: mdl-12114523
19.
Regulation of the FoxO family of transcription factors by phosphatidylinositol-3 kinase-activated signaling.
Arch Biochem Biophys
; 403(2): 292-8, 2002 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-12139979