Detalhe da pesquisa
1.
Evinacumab for Pediatric Patients With Homozygous Familial Hypercholesterolemia.
Circulation
; 149(5): 343-353, 2024 01 30.
Artigo
Inglês
| MEDLINE | ID: mdl-37860863
2.
Exposure-response Modeling From the CLARITY Trial of Pimavanserin for Adjunctive Treatment of Major Depressive Disorder.
Clin Pharmacol Drug Dev
; 12(5): 463-474, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36880278
3.
Population pharmacokinetics of molnupiravir in adults with COVID-19: Lack of clinically important exposure variation across individuals.
CPT Pharmacometrics Syst Pharmacol
; 12(12): 1859-1871, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37798914
4.
Population Pharmacokinetic Modeling and Exposure-Response Analysis for Aripiprazole Once Monthly in Subjects With Schizophrenia.
Clin Pharmacol Drug Dev
; 11(2): 150-164, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34979059
5.
Mechanism-based disease progression modeling of type 2 diabetes in Goto-Kakizaki rats.
J Pharmacokinet Pharmacodyn
; 38(1): 143-62, 2011 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-21127951
6.
Population Pharmacokinetic Analysis of BMS-986166, a Novel Selective Sphingosine-1-Phosphate-1 Receptor Modulator, and Exposure-Response Assessment of Lymphocyte Counts and Heart Rate in Healthy Participants.
Clin Pharmacol Drug Dev
; 10(1): 8-21, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33090733
7.
Population Pharmacokinetic Analysis of the Cathepsin K Inhibitor Odanacatib: Insights Into Intrinsic and Extrinsic Factor Effects on Exposure in Postmenopausal and Elderly Women.
J Clin Pharmacol
; 60(8): 1107-1123, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32302427
8.
Population pharmacokinetic modeling of LY2189102 after multiple intravenous and subcutaneous administrations.
AAPS J
; 16(5): 1009-17, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24912797
9.
ABC transporters and the accumulation of imatinib and its active metabolite CGP74588 in rat C6 glioma cells.
Pharmacol Res
; 57(3): 214-22, 2008 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-18337118
10.
Influence of breast cancer resistance protein (Abcg2) and p-glycoprotein (Abcb1a) on the transport of imatinib mesylate (Gleevec) across the mouse blood-brain barrier.
J Neurochem
; 102(6): 1749-1757, 2007 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-17696988
11.
Modulation of the brain distribution of imatinib and its metabolites in mice by valspodar, zosuquidar and elacridar.
Pharm Res
; 24(9): 1720-8, 2007 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-17380257
12.
Influence of hydroxyurea on imatinib mesylate (gleevec) transport at the mouse blood-brain barrier.
Drug Metab Dispos
; 34(12): 1945-9, 2006 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-16936068