Detalhe da pesquisa
1.
A Phase 2, Randomized, Multicenter, Placebo-Controlled, Proof-of-Concept Trial of Oral Fexinidazole in Adults With Chronic Indeterminate Chagas Disease.
Clin Infect Dis
; 76(3): e1186-e1194, 2023 02 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35925555
2.
Recent Development of Visceral Leishmaniasis Treatments: Successes, Pitfalls, and Perspectives.
Clin Microbiol Rev
; 31(4)2018 10.
Artigo
Inglês
| MEDLINE | ID: mdl-30158301
3.
Quantifying the Infectiousness of Post-Kala-Azar Dermal Leishmaniasis Toward Sand Flies.
Clin Infect Dis
; 69(2): 251-258, 2019 07 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30357373
4.
AFQ056/mavoglurant, a novel clinically effective mGluR5 antagonist: identification, SAR and pharmacological characterization.
Bioorg Med Chem
; 22(21): 5790-803, 2014 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25316499
5.
The Pandemic Response BoxâAccelerating Drug Discovery Efforts after Disease Outbreaks.
ACS Infect Dis
; 8(4): 713-720, 2022 04 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35286809
6.
New regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease (BENDITA): a phase 2, double-blind, randomised trial.
Lancet Infect Dis
; 21(8): 1129-1140, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33836161
7.
CpG ODN D35 improves the response to abbreviated low-dose pentavalent antimonial treatment in non-human primate model of cutaneous leishmaniasis.
PLoS Negl Trop Dis
; 14(2): e0008050, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32109251
8.
Implications of asymptomatic infection for the natural history of selected parasitic tropical diseases.
Semin Immunopathol
; 42(3): 231-246, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32189034
9.
Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis.
Pharmacol Ther
; 117(1): 77-93, 2008 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-17961662
10.
The selective nicotinic acetylcholine receptor alpha7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain.
Neuropharmacology
; 56(1): 254-63, 2009 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-18793655
11.
Single-step detection of mutant huntingtin in animal and human tissues: a bioassay for Huntington's disease.
Anal Biochem
; 395(1): 8-15, 2009 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19664996
12.
mGluR5 antagonists: discovery, characterization and drug development.
Curr Opin Drug Discov Devel
; 11(5): 655-65, 2008 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-18729017
13.
Tres Cantos Open Lab: celebrating a decade of innovation in collaboration to combat endemic infectious diseases.
Nat Rev Drug Discov
; 20(11): 799-800, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34471283
14.
AQW051, a novel, potent and selective α7 nicotinic ACh receptor partial agonist: pharmacological characterization and phase I evaluation.
Br J Pharmacol
; 172(5): 1292-304, 2015 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25363835
15.
At issue: A model for academic/industry collaboration.
Schizophr Bull
; 30(4): 997-1004, 2004.
Artigo
Inglês
| MEDLINE | ID: mdl-15954203
16.
Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progression.
J Clin Invest
; 122(10): 3731-6, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22996692
17.
The acute antiparkinsonian and antidyskinetic effect of AFQ056, a novel metabotropic glutamate receptor type 5 antagonist, in L-Dopa-treated parkinsonian monkeys.
Parkinsonism Relat Disord
; 17(4): 270-6, 2011 May.
Artigo
Inglês
| MEDLINE | ID: mdl-21315648
18.
Metabotropic glutamate receptor type 5 in levodopa-induced motor complications.
Neurobiol Aging
; 32(7): 1286-95, 2011 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20036444
19.
Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056.
Sci Transl Med
; 3(64): 64ra1, 2011 Jan 05.
Artigo
Inglês
| MEDLINE | ID: mdl-21209411
20.
Infectious diseases. Overcoming neglect of kinetoplastid diseases.
Science
; 348(6238): 974-6, 2015 May 29.
Artigo
Inglês
| MEDLINE | ID: mdl-26023124