1.
Chemistry
; 20(51): 17119-24, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25345835
RESUMO
An enantioselective total synthesis of the natural (+)-linoxepin (1) was accomplished in eleven steps from bromovanin (24). Key steps are a domino carbopalladation/ Mizoroki-Heck reaction with the formation of a pentacyclic system, an asymmetric hydroboration as well as an oxidative lactonization.