Detalhe da pesquisa
1.
Targeting WEE1 kinase as a p53-independent therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia.
Cancer Cell Int
; 23(1): 202, 2023 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37715172
2.
Synthesis and In Vivo Evaluation of a Site-specifically Labeled Radioimmunoconjugate for Dual-Modal (PET/NIRF) Imaging of MT1-MMP in Sarcomas.
Bioconjug Chem
; 33(8): 1564-1573, 2022 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35867034
3.
Paediatric Burkitt lymphoma patient-derived xenografts capture disease characteristics over time and are a model for therapy.
Br J Haematol
; 192(2): 354-365, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32880915
4.
Phase II-like murine trial identifies synergy between dexamethasone and dasatinib in T-cell acute lymphoblastic leukemia.
Haematologica
; 106(4): 1056-1066, 2021 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32139432
5.
Glucocorticoids and selumetinib are highly synergistic in RAS pathway-mutated childhood acute lymphoblastic leukemia through upregulation of BIM.
Haematologica
; 104(9): 1804-1811, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30655370
6.
The ability to cross the blood-cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts.
Blood
; 127(16): 1998-2006, 2016 Apr 21.
Artigo
Inglês
| MEDLINE | ID: mdl-26869395
7.
Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.
Haematologica
; 103(4): 634-644, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29449437
8.
Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma.
Haematologica
; 102(7): 1247-1257, 2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28385782
9.
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition.
Blood
; 124(23): 3420-30, 2014 Nov 27.
Artigo
Inglês
| MEDLINE | ID: mdl-25253770
10.
Combination p53 activation and BCL-xL/BCL-2 inhibition as a therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia.
Leukemia
; 38(6): 1223-1235, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38600316
11.
Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1.
iScience
; 27(4): 109576, 2024 Apr 19.
Artigo
Inglês
| MEDLINE | ID: mdl-38638836
12.
Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth.
Nat Commun
; 15(1): 1359, 2024 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38355578
13.
Nanoparticle-mediated targeting of the fusion gene RUNX1/ETO in t(8;21)-positive acute myeloid leukaemia.
Leukemia
; 37(4): 820-834, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36823395
14.
The MLL-Menin Interaction is a Therapeutic Vulnerability in NUP98-rearranged AML.
Hemasphere
; 7(8): e935, 2023 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-37520776
15.
Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.
bioRxiv
; 2023 Jul 19.
Artigo
Inglês
| MEDLINE | ID: mdl-37503022
16.
Disruption to the FOXO-PRDM1 axis resulting from deletions of chromosome 6 in acute lymphoblastic leukaemia.
Leukemia
; 37(3): 636-649, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36670235
17.
Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.
Cell Rep
; 42(12): 113568, 2023 12 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38104314
18.
Biallelic TET2 mutations confer sensitivity to 5'-azacitidine in acute myeloid leukemia.
JCI Insight
; 8(2)2023 Jan 24.
Artigo
Inglês
| MEDLINE | ID: mdl-36480300
19.
Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus.
BMC Biol
; 9: 14, 2011 Feb 28.
Artigo
Inglês
| MEDLINE | ID: mdl-21356043
20.
A human mesenchymal spheroid prototype to replace moderate severity animal procedures in leukaemia drug testing.
F1000Res
; 11: 1280, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-38046539