Detalhe da pesquisa
1.
A Phase 3, Randomized Trial of Bulevirtide in Chronic Hepatitis D.
N Engl J Med
; 389(1): 22-32, 2023 Jul 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37345876
2.
Bulevirtide monotherapy in patients with chronic HDV: Efficacy and safety results through week 96 from a phase 3 randomized trial.
J Hepatol
; 2024 May 09.
Artigo
Inglês
| MEDLINE | ID: mdl-38734383
3.
Acute antiarrhythmic effects of SGLT2 inhibitors-dapagliflozin lowers the excitability of atrial cardiomyocytes.
Basic Res Cardiol
; 119(1): 93-112, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38170280
4.
Extracellular Vesicles as Surrogates for the Regulation of the Drug Transporters ABCC2 (MRP2) and ABCG2 (BCRP).
Int J Mol Sci
; 25(7)2024 Apr 08.
Artigo
Inglês
| MEDLINE | ID: mdl-38612927
5.
Time course of CYP3A activity during and after metamizole (dipyrone) in healthy volunteers.
Br J Clin Pharmacol
; 89(8): 2458-2464, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36946257
6.
Effect of Clarithromycin, a Strong CYP3A and P-glycoprotein Inhibitor, on the Pharmacokinetics of Edoxaban in Healthy Volunteers and the Evaluation of the Drug Interaction with Other Oral Factor Xa Inhibitors by a Microdose Cocktail Approach.
Cardiovasc Drugs Ther
; 2023 Mar 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36870039
7.
Influence of a Short Course of Ritonavir Used as Booster in Antiviral Therapies Against SARS-CoV-2 on the Exposure of Atorvastatin and Rosuvastatin.
Cardiovasc Drugs Ther
; 2023 Dec 19.
Artigo
Inglês
| MEDLINE | ID: mdl-38112932
8.
Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans.
Eur J Clin Pharmacol
; 78(6): 975-987, 2022 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-35238961
9.
Oral bioavailability of microdoses and therapeutic doses of midazolam as a 2-dimensionally printed orodispersible film in healthy volunteers.
Eur J Clin Pharmacol
; 78(12): 1965-1972, 2022 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-36258053
10.
Metabolic Effect of Blocking Sodium-Taurocholate Co-Transporting Polypeptide in Hypercholesterolemic Humans with a Twelve-Week Course of Bulevirtide-An Exploratory Phase I Clinical Trial.
Int J Mol Sci
; 23(24)2022 Dec 14.
Artigo
Inglês
| MEDLINE | ID: mdl-36555566
11.
Intact plasma quantification of the large therapeutic lipopeptide bulevirtide.
Anal Bioanal Chem
; 413(22): 5645-5654, 2021 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-34018034
12.
Simultaneous phenotyping of CYP2E1 and CYP3A using oral chlorzoxazone and midazolam microdoses.
Br J Clin Pharmacol
; 85(10): 2310-2320, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31222796
13.
Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice.
Hepatology
; 66(5): 1631-1643, 2017 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28498614
14.
Autoinhibitory properties of the parent but not of the N-oxide metabolite contribute to infusion rate-dependent voriconazole pharmacokinetics.
Br J Clin Pharmacol
; 83(9): 1954-1965, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28370390
15.
Cost-effectiveness of an electronic clinical decision support system for improving quality of antenatal and childbirth care in rural Tanzania: an intervention study.
BMC Health Serv Res
; 17(1): 537, 2017 Aug 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28784130
16.
First-in-human application of the novel hepatitis B and hepatitis D virus entry inhibitor myrcludex B.
J Hepatol
; 65(3): 483-9, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27132172
17.
Treatment of chronic hepatitis D with the entry inhibitor myrcludex B: First results of a phase Ib/IIa study.
J Hepatol
; 65(3): 490-8, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27132170
18.
Quality of antenatal and childbirth care in rural health facilities in Burkina Faso, Ghana and Tanzania: an intervention study.
Trop Med Int Health
; 21(1): 70-83, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26503485
19.
Quantitative bile acid profiling by liquid chromatography quadrupole time-of-flight mass spectrometry: monitoring hepatitis B therapy by a novel Na(+)-taurocholate cotransporting polypeptide inhibitor.
Anal Bioanal Chem
; 407(22): 6815-25, 2015 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-26143062
20.
Cost of installing and operating an electronic clinical decision support system for maternal health care: case of Tanzania rural primary health centres.
BMC Health Serv Res
; 15: 132, 2015 Apr 02.
Artigo
Inglês
| MEDLINE | ID: mdl-25888762