Detalhe da pesquisa
1.
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
N Engl J Med
; 387(21): 1923-1934, 2022 Nov 24.
Artigo
Inglês
| MEDLINE | ID: mdl-36342113
2.
Worldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study.
Lancet
; 399(10326): 719-728, 2022 02 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35101175
3.
Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome.
N Engl J Med
; 381(6): 531-542, 2019 08 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31390500
4.
Genetic and Mechanistic Insights into the Modulation of Circulating Lipoprotein (a) Concentration by Apolipoprotein E Isoforms.
Curr Atheroscler Rep
; 24(6): 399-405, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35355214
5.
Novel PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Variants in Patients With Familial Hypercholesterolemia From Cape Town.
Arterioscler Thromb Vasc Biol
; 41(2): 934-943, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33147992
6.
Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia.
N Engl J Med
; 376(17): 1647-1658, 2017 04 27.
Artigo
Inglês
| MEDLINE | ID: mdl-28402248
7.
Lomitapide and Mipomersen-Inhibiting Microsomal Triglyceride Transfer Protein (MTP) and apoB100 Synthesis.
Curr Atheroscler Rep
; 21(12): 48, 2019 11 19.
Artigo
Inglês
| MEDLINE | ID: mdl-31741187
8.
Homozygous Familial Hypercholesterolemia Patients With Identical Mutations Variably Express the LDLR (Low-Density Lipoprotein Receptor): Implications for the Efficacy of Evolocumab.
Arterioscler Thromb Vasc Biol
; 38(3): 592-598, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29284604
9.
Survival in homozygous familial hypercholesterolaemia is determined by the on-treatment level of serum cholesterol.
Eur Heart J
; 39(14): 1162-1168, 2018 04 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29106543
10.
Efficacy and safety of evolocumab in reducing lipids and cardiovascular events.
N Engl J Med
; 372(16): 1500-9, 2015 Apr 16.
Artigo
Inglês
| MEDLINE | ID: mdl-25773607
11.
A 52-week placebo-controlled trial of evolocumab in hyperlipidemia.
N Engl J Med
; 370(19): 1809-19, 2014 May 08.
Artigo
Inglês
| MEDLINE | ID: mdl-24678979
12.
Effects of Evolocumab on Vitamin E and Steroid Hormone Levels: Results From the 52-Week, Phase 3, Double-Blind, Randomized, Placebo-Controlled DESCARTES Study.
Circ Res
; 117(8): 731-41, 2015 Sep 25.
Artigo
Inglês
| MEDLINE | ID: mdl-26228031
13.
Evaluation of the efficacy, safety and glycaemic effects of evolocumab (AMG 145) in hypercholesterolaemic patients stratified by glycaemic status and metabolic syndrome.
Diabetes Obes Metab
; 19(1): 98-107, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27619750
14.
Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial.
Lancet
; 385(9965): 341-50, 2015 Jan 24.
Artigo
Inglês
| MEDLINE | ID: mdl-25282520
15.
Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study.
Lancet
; 381(9860): 40-6, 2013 Jan 05.
Artigo
Inglês
| MEDLINE | ID: mdl-23122768
16.
Recent advances in the treatment of homozygous familial hypercholesterolaemia.
Curr Opin Lipidol
; 24(4): 288-94, 2013 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-23839331
17.
Sex Differences in Diagnosis, Treatment, and Cardiovascular Outcomes in Homozygous Familial Hypercholesterolemia.
JAMA Cardiol
; 9(4): 313-322, 2024 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38353972
18.
Long-Term Efficacy and Safety of the Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide in Patients With Homozygous Familial Hypercholesterolemia.
Circulation
; 136(3): 332-335, 2017 07 18.
Artigo
Inglês
| MEDLINE | ID: mdl-28716835
19.
Proprotein convertase subtilisin/kexin type 9 inhibition.
Curr Opin Lipidol
; 23(6): 511-7, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-22907332
20.
International Atherosclerosis Society guidance for implementing best practice in the care of familial hypercholesterolaemia.
Nat Rev Cardiol
; 20(12): 845-869, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37322181