Detalhe da pesquisa
1.
PCSK9 ablation attenuates Aß pathology, neuroinflammation and cognitive dysfunctions in 5XFAD mice.
Brain Behav Immun
; 115: 517-534, 2024 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37967665
2.
Identification of 4-amino-2-Pyridones as new potent PCSK9 inhibitors: From phenotypic hit discovery to in vivo tolerability.
Eur J Med Chem
; 265: 116063, 2024 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-38160616
3.
Evidence for a protective effect of the loss of α4-containing nicotinic acetylcholine receptors on Aß-related neuropathology in Tg2576 mice.
Front Neurosci
; 17: 1097857, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37113156
4.
Melanocortin receptor agonist NDP-α-MSH improves cognitive deficits and microgliosis but not amyloidosis in advanced stages of AD progression in 5XFAD and 3xTg mice.
Front Immunol
; 13: 1082036, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36703981
5.
S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis.
Transl Psychiatry
; 11(1): 562, 2021 11 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34741005
6.
Identification of a Thyroid Hormone Derivative as a Pleiotropic Agent for the Treatment of Alzheimer's Disease.
Pharmaceuticals (Basel)
; 14(12)2021 Dec 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34959730