Detalhe da pesquisa
1.
The T Cell Antigen Receptor α Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations.
Immunity
; 49(5): 829-841.e6, 2018 11 20.
Artigo
Inglês
| MEDLINE | ID: mdl-30389415
2.
An open-source drug discovery platform enables ultra-large virtual screens.
Nature
; 580(7805): 663-668, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32152607
3.
Aromatic 19F-13C TROSY: a background-free approach to probe biomolecular structure, function, and dynamics.
Nat Methods
; 16(4): 333-340, 2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30858598
4.
Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction.
Nature
; 530(7591): 485-9, 2016 Feb 25.
Artigo
Inglês
| MEDLINE | ID: mdl-26886795
5.
15N detection harnesses the slow relaxation property of nitrogen: Delivering enhanced resolution for intrinsically disordered proteins.
Proc Natl Acad Sci U S A
; 115(8): E1710-E1719, 2018 02 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29432148
6.
The precious fluorine on the ring: fluorine NMR for biological systems.
J Biomol NMR
; 74(8-9): 365-379, 2020 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-32651751
7.
Structural basis for LeishIF4E-1 modulation by an interacting protein in the human parasite Leishmania major.
Nucleic Acids Res
; 46(7): 3791-3801, 2018 04 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29562352
8.
Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication.
Proc Natl Acad Sci U S A
; 112(29): 9010-5, 2015 Jul 21.
Artigo
Inglês
| MEDLINE | ID: mdl-26150520
9.
Structure of a CGI-58 motif provides the molecular basis of lipid droplet anchoring.
J Biol Chem
; 290(44): 26361-72, 2015 Oct 30.
Artigo
Inglês
| MEDLINE | ID: mdl-26350461
10.
Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling.
J Biol Chem
; 290(30): 18438-53, 2015 Jul 24.
Artigo
Inglês
| MEDLINE | ID: mdl-25953897
11.
CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization.
J Lipid Res
; 56(1): 109-21, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25421061
12.
A peptide derived from G0/G1 switch gene 2 acts as noncompetitive inhibitor of adipose triglyceride lipase.
J Biol Chem
; 289(47): 32559-70, 2014 Nov 21.
Artigo
Inglês
| MEDLINE | ID: mdl-25258314
13.
Increased resolution of aromatic cross peaks using alternate 13C labeling and TROSY.
J Biomol NMR
; 62(3): 291-301, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25957757
14.
"Multiplexed screen identifies a Pseudomonas aeruginosa -specific small molecule targeting the outer membrane protein OprH and its interaction with LPS".
bioRxiv
; 2024 Mar 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38559044
15.
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells.
Science
; 384(6694): eadk5864, 2024 Apr 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38662832
16.
The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes.
Biochim Biophys Acta
; 1821(7): 1012-21, 2012 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-22561231
17.
A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity.
Nat Commun
; 14(1): 6626, 2023 10 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37863876
18.
Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors.
Cell Chem Biol
; 30(8): 953-964.e9, 2023 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-37516113
19.
Recent insights into the structure and function of comparative gene identification-58.
Curr Opin Lipidol
; 22(3): 149-58, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21494142
20.
The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability.
iScience
; 24(11): 103338, 2021 Nov 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34805795