Detalhe da pesquisa
1.
Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.
Cell
; 135(1): 49-60, 2008 Oct 03.
Artigo
Inglês
| MEDLINE | ID: mdl-18854154
2.
The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα.
Nature
; 541(7638): 541-545, 2017 01 26.
Artigo
Inglês
| MEDLINE | ID: mdl-28068668
3.
A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis.
Nature
; 546(7658): 376-380, 2017 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28562588
4.
Imidazolopiperazines Kill both Rings and Dormant Rings in Wild-Type and K13 Artemisinin-Resistant Plasmodium falciparum In Vitro.
Antimicrob Agents Chemother
; 62(5)2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29530849
5.
Discovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hit.
Bioorg Med Chem Lett
; 27(6): 1385-1389, 2017 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28216045
6.
Determining the distribution of probes between different subcellular locations through automated unmixing of subcellular patterns.
Proc Natl Acad Sci U S A
; 107(7): 2944-9, 2010 Feb 16.
Artigo
Inglês
| MEDLINE | ID: mdl-20133616
7.
Efficacy of HD201 vs Referent Trastuzumab in Patients With ERBB2-Positive Breast Cancer Treated in the Neoadjuvant Setting: A Multicenter Phase 3 Randomized Clinical Trial.
JAMA Oncol
; 8(5): 698-705, 2022 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35238873
8.
NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models.
Sci Transl Med
; 13(579)2021 02 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33536278
9.
Development of a Cytopathic Effect-Based Phenotypic Screening Assay against Cryptosporidium.
ACS Infect Dis
; 4(4): 635-645, 2018 04 13.
Artigo
Inglês
| MEDLINE | ID: mdl-29341586
10.
A small molecule promotes mitochondrial fusion in mammalian cells.
Angew Chem Int Ed Engl
; 51(37): 9302-5, 2012 Sep 10.
Artigo
Inglês
| MEDLINE | ID: mdl-22907892
11.
Identification of SPPL2a Inhibitors by Multiparametric Analysis of a High-Content Ultra-High-Throughput Screen.
SLAS Discov
; 22(9): 1106-1119, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-28731783
12.
The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase.
Cell Rep
; 19(3): 451-460, 2017 04 18.
Artigo
Inglês
| MEDLINE | ID: mdl-28423309
13.
A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi.
Elife
; 62017 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29215331
14.
Cancer promoted by the oncoprotein v-ErbA may be due to subcellular mislocalization of nuclear receptors.
Mol Endocrinol
; 19(5): 1213-30, 2005 May.
Artigo
Inglês
| MEDLINE | ID: mdl-15650025
15.
UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes.
Nat Microbiol
; 1: 16166, 2016 Sep 19.
Artigo
Inglês
| MEDLINE | ID: mdl-27642791
16.
FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells.
PLoS One
; 8(1): e51671, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23300950
17.
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP.
Chem Biol
; 19(8): 955-62, 2012 Aug 24.
Artigo
Inglês
| MEDLINE | ID: mdl-22884261
18.
Cofactors required for TLR7- and TLR9-dependent innate immune responses.
Cell Host Microbe
; 11(3): 306-18, 2012 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22423970
19.
A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor.
ACS Chem Biol
; 6(11): 1214-22, 2011 Nov 18.
Artigo
Inglês
| MEDLINE | ID: mdl-21866942
20.
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
Science
; 334(6061): 1372-7, 2011 Dec 09.
Artigo
Inglês
| MEDLINE | ID: mdl-22096101