Detalhe da pesquisa
1.
Neuroprotective Effects of Transferrin in Experimental Glaucoma Models.
Int J Mol Sci
; 23(21)2022 Oct 22.
Artigo
Inglês
| MEDLINE | ID: mdl-36361544
2.
Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat.
Brain
; 138(Pt 12): 3632-53, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26490331
3.
Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons.
Neurobiol Dis
; 69: 263-75, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24844147
4.
Olesoxime accelerates myelination and promotes repair in models of demyelination.
Ann Neurol
; 71(2): 213-26, 2012 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22367994
5.
Neuromuscular defects and breathing disorders in a new mouse model of spinal muscular atrophy.
Neurobiol Dis
; 38(1): 125-35, 2010 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-20085811
6.
TRO40303, a new cardioprotective compound, inhibits mitochondrial permeability transition.
J Pharmacol Exp Ther
; 333(3): 696-706, 2010 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-20215409
7.
[Anti-TNF-α in the treatment of non-infectious uveitis]. / Les anti-TNF-α pour le traitement des uvéites non infectieuses.
Med Sci (Paris)
; 36(10): 893-899, 2020 Oct.
Artigo
Francês
| MEDLINE | ID: mdl-33026332
8.
Transferrin Non-Viral Gene Therapy for Treatment of Retinal Degeneration.
Pharmaceutics
; 12(9)2020 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32882879
9.
Ocular gene therapies in clinical practice: viral vectors and nonviral alternatives.
Drug Discov Today
; 24(8): 1685-1693, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31173914
10.
Preclinical Development of an AAV8-hUGT1A1 Vector for the Treatment of Crigler-Najjar Syndrome.
Mol Ther Methods Clin Dev
; 12: 157-174, 2019 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30705921
11.
Specific antinociceptive activity of cholest-4-en-3-one, oxime (TRO19622) in experimental models of painful diabetic and chemotherapy-induced neuropathy.
J Pharmacol Exp Ther
; 326(2): 623-32, 2008 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-18492948
12.
Non-viral ocular gene therapy, pEYS606, for the treatment of non-infectious uveitis: Preclinical evaluation of the medicinal product.
J Control Release
; 285: 244-251, 2018 09 10.
Artigo
Inglês
| MEDLINE | ID: mdl-30009894
13.
TRO40303 Ameliorates Alcohol-Induced Pancreatitis Through Reduction of Fatty Acid Ethyl Ester-Induced Mitochondrial Injury and Necrotic Cell Death.
Pancreas
; 47(1): 18-24, 2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29200128
14.
Gene Therapy for Uveitis.
Int Ophthalmol Clin
; 61(4): 249-270, 2021 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34584061
15.
Differences in the profile of protection afforded by TRO40303 and mild hypothermia in models of cardiac ischemia/reperfusion injury.
Eur J Pharmacol
; 760: 7-19, 2015 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25895640
16.
Adenoviral and adeno-associated viral vector mediated gene transfer in the guinea pig cochlea.
Neuroreport
; 13(10): 1295-9, 2002 Jul 19.
Artigo
Inglês
| MEDLINE | ID: mdl-12151790
17.
Mitochondrial membrane fluidity is consistently increased in different models of Huntington disease: restorative effects of olesoxime.
Mol Neurobiol
; 50(1): 107-18, 2014 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-24633813
18.
Olesoxime protects embryonic cortical neurons from camptothecin intoxication by a mechanism distinct from BDNF.
Br J Pharmacol
; 168(8): 1975-88, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23278424
19.
Early deficits in glycolysis are specific to striatal neurons from a rat model of huntington disease.
PLoS One
; 8(11): e81528, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24303051
20.
Olesoxime (TRO19622): A Novel Mitochondrial-Targeted Neuroprotective Compound.
Pharmaceuticals (Basel)
; 3(2): 345-368, 2010 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-27713255