Detalhe da pesquisa
1.
BTK inhibition limits microglia-perpetuated CNS inflammation and promotes myelin repair.
Acta Neuropathol
; 147(1): 75, 2024 Apr 24.
Artigo
Inglês
| MEDLINE | ID: mdl-38656399
2.
Imaging meningeal inflammation in CNS autoimmunity identifies a therapeutic role for BTK inhibition.
Brain
; 144(5): 1396-1408, 2021 06 22.
Artigo
Inglês
| MEDLINE | ID: mdl-33724342
3.
Inhibition of Bruton's tyrosine kinase interferes with pathogenic B-cell development in inflammatory CNS demyelinating disease.
Acta Neuropathol
; 140(4): 535-548, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32761407
4.
Seizures and disturbed brain potassium dynamics in the leukodystrophy megalencephalic leukoencephalopathy with subcortical cysts.
Ann Neurol
; 83(3): 636-649, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29466841
5.
Varicella zoster virus and influenza vaccine antibody titres in patients from MAGNIFY-MS who were treated with cladribine tablets for highly active relapsing multiple sclerosis.
Mult Scler
; 28(13): 2151-2153, 2022 11.
Artigo
Inglês
| MEDLINE | ID: mdl-35672923
6.
Immunohistochemical detection of sphingosine-1-phosphate receptor 1 and 5 in human multiple sclerosis lesions.
Neuropathol Appl Neurobiol
; 40(5): 564-78, 2014 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-23551178
7.
A plain language summary of the impact of vaccines against flu and chickenpox in people with multiple sclerosis treated with cladribine tablets.
Neurodegener Dis Manag
; 13(1): 15-21, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36545912
8.
Revealing the immune cell subtype reconstitution profile in patients from the CLARITY study using deconvolution algorithms after cladribine tablets treatment.
Sci Rep
; 13(1): 8067, 2023 05 18.
Artigo
Inglês
| MEDLINE | ID: mdl-37202447
9.
Molecular signature associated with cladribine treatment in patients with multiple sclerosis.
Front Immunol
; 14: 1233546, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37559720
10.
Specific Patterns of Immune Cell Dynamics May Explain the Early Onset and Prolonged Efficacy of Cladribine Tablets: A MAGNIFY-MS Substudy.
Neurol Neuroimmunol Neuroinflamm
; 10(1)2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36411081
11.
Different Susceptibility of T and B Cells to Cladribine Depends On Their Levels of Deoxycytidine Kinase Activity Linked to Activation Status.
J Neuroimmune Pharmacol
; 17(1-2): 195-205, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33851318
12.
Human T-bet+ B cell development is associated with BTK activity and suppressed by evobrutinib.
JCI Insight
; 7(16)2022 08 22.
Artigo
Inglês
| MEDLINE | ID: mdl-35852869
13.
Immunomodulatory Effects Associated with Cladribine Treatment.
Cells
; 10(12)2021 12 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34943995
14.
In vivo processing of CXCL12α/SDF-1α after intravenous and subcutaneous administration to mice.
Proteomics
; 10(24): 4342-51, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-21136589
15.
Bruton's Tyrosine Kinase Inhibition Promotes Myelin Repair.
Brain Plast
; 5(2): 123-133, 2020 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33282676
16.
Non-invasive visual evoked potentials to assess optic nerve involvement in the dark agouti rat model of experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein.
Brain Pathol
; 30(1): 137-150, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31267597
17.
Effects of cladribine tablets on lymphocyte subsets in patients with multiple sclerosis: an extended analysis of surface markers.
Ther Adv Neurol Disord
; 12: 1756286419854986, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31244898
18.
Megalencephalic leukoencephalopathy with cysts: the Glialcam-null mouse model.
Ann Clin Transl Neurol
; 4(7): 450-465, 2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28695146
19.
Differential effects of chemokines on oligodendrocyte precursor proliferation and myelin formation in vitro.
J Neuroimmunol
; 174(1-2): 133-46, 2006 May.
Artigo
Inglês
| MEDLINE | ID: mdl-16574247
20.
Effect of ceralifimod (ONO-4641) on lymphocytes and cardiac function: Randomized, double-blind, placebo-controlled trial with an open-label fingolimod arm.
J Clin Pharmacol
; 55(9): 1051-60, 2015 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-25855155