Detalhe da pesquisa
1.
Identification of Novel Non-Nucleoside Inhibitors of Zika Virus NS5 Protein Targeting MTase Activity.
Int J Mol Sci
; 25(4)2024 Feb 19.
Artigo
Inglês
| MEDLINE | ID: mdl-38397115
2.
A chalcone derivative binds a putative allosteric site of YopH: Inhibition of a virulence factor of Yersinia.
Bioorg Med Chem Lett
; 30(16): 127350, 2020 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32631548
3.
Discovery of small molecule inhibitors of Leishmania braziliensis Hsp90 chaperone.
J Enzyme Inhib Med Chem
; 35(1): 639-649, 2020 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-32048531
4.
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.
EMBO J
; 34(2): 200-17, 2015 Jan 13.
Artigo
Inglês
| MEDLINE | ID: mdl-25476449
5.
A Molecular Tool Targeting the Base-Flipping Activity of Human UHRF1.
Chemistry
; 25(58): 13363-13375, 2019 Oct 17.
Artigo
Inglês
| MEDLINE | ID: mdl-31322780
6.
Synthesis of distal and proximal fleximer base analogues and evaluation in the nucleocapsid protein of HIV-1.
Bioorg Med Chem
; 27(13): 2883-2892, 2019 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31126822
7.
Chemically stable inhibitors of 14-3-3 protein-protein interactions derived from BV02.
J Enzyme Inhib Med Chem
; 34(1): 657-664, 2019 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-30727786
8.
Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents.
Proc Natl Acad Sci U S A
; 113(19): 5388-93, 2016 May 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27118832
9.
Proton Therapy and Src Family Kinase Inhibitor Combined Treatments on U87 Human Glioblastoma Multiforme Cell Line.
Int J Mol Sci
; 20(19)2019 09 24.
Artigo
Inglês
| MEDLINE | ID: mdl-31554327
10.
Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X.
Molecules
; 24(21)2019 Nov 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31690062
11.
Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1.
Bioorg Med Chem Lett
; 28(4): 637-641, 2018 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29395975
12.
Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment.
Bioorg Med Chem Lett
; 28(21): 3454-3457, 2018 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30262428
13.
SRC Family Kinase Inhibition in Ewing Sarcoma Cells Induces p38 MAP Kinase-Mediated Cytotoxicity and Reduces Cell Migration.
J Cell Physiol
; 232(1): 129-35, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27037775
14.
Hematopoietic cell kinase (HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/PI3K pathway and regulation of erythropoiesis: HCK in erythropoietin/PI3K pathway.
Biochim Biophys Acta Mol Basis Dis
; 1863(2): 450-461, 2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27840303
15.
Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding.
Chembiochem
; 18(4): 374-377, 2017 02 16.
Artigo
Inglês
| MEDLINE | ID: mdl-27992102
16.
Pyrazolo[3,4-d]pyrimidines-loaded human serum albumin (HSA) nanoparticles: Preparation, characterization and cytotoxicity evaluation against neuroblastoma cell line.
Bioorg Med Chem Lett
; 27(14): 3196-3200, 2017 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28558969
17.
Design and synthesis of a novel inhibitor of T. Viride chitinase through an in silico target fishing protocol.
Bioorg Med Chem Lett
; 27(15): 3332-3336, 2017 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28610983
18.
Potent and Selective Carboxylic Acid Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII.
Molecules
; 23(1)2017 Dec 22.
Artigo
Inglês
| MEDLINE | ID: mdl-29271882
19.
Novel Sulfamide-Containing Compounds as Selective Carbonic Anhydrase I Inhibitors.
Molecules
; 22(7)2017 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-28672822
20.
Inhibition of HIV-1 Reverse Transcriptase Dimerization by Small Molecules.
Chembiochem
; 17(8): 683-8, 2016 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26946324