Detalhe da pesquisa
1.
VXX-401, a novel anti-PCSK9 vaccine, reduces LDL-C in cynomolgus monkeys.
J Lipid Res
; 65(2): 100497, 2024 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38216056
2.
Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons.
Neurobiol Dis
; 111: 26-35, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29246723
3.
Optimizing the Cell Painting assay for image-based profiling.
Nat Protoc
; 18(7): 1981-2013, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37344608
4.
A high content drug screen identifies ursolic acid as an inhibitor of amyloid beta protein interactions with its receptor CD36.
J Biol Chem
; 286(40): 34914-22, 2011 Oct 07.
Artigo
Inglês
| MEDLINE | ID: mdl-21835916
5.
GW5074 Increases Microglial Phagocytic Activities: Potential Therapeutic Direction for Alzheimer's Disease.
Front Cell Neurosci
; 16: 894601, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35677758
6.
Isoflurane decreases self-renewal capacity of rat cultured neural stem cells.
Anesthesiology
; 115(4): 754-63, 2011 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-21666433
7.
Image-based profiling for drug discovery: due for a machine-learning upgrade?
Nat Rev Drug Discov
; 20(2): 145-159, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33353986
8.
Generating neurons from stem cells.
Methods Mol Biol
; 438: 31-8, 2008.
Artigo
Inglês
| MEDLINE | ID: mdl-18369747
9.
Oxytocin alters cell fate selection of rat neural progenitor cells in vitro.
PLoS One
; 13(1): e0191160, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29346405
10.
Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta.
Brain Res
; 1175: 107-16, 2007 Oct 17.
Artigo
Inglês
| MEDLINE | ID: mdl-17884023
11.
A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.
Sci Transl Med
; 9(421)2017 Dec 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29263232
12.
Advances in High-Content Imaging and Informatics: A Joint Special Collection with Society for Biomolecular Imaging and Informatics and SLAS.
SLAS Discov
; 26(9): 1073-1075, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34543135
13.
Prolonged Treatment with Propofol Transiently Impairs Proliferation but Not Survival of Rat Neural Progenitor Cells In Vitro.
PLoS One
; 11(7): e0158058, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27379684
14.
Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.
Cell Rep
; 12(9): 1414-29, 2015 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26299970
15.
Society of Biomolecular Imaging and Informatics High-Content Screening/High-Content Analysis Preclinical Translational Imaging Colloquium: How Emerging Technologies in Disease Models, High-Content Imaging, and Data Analytics Are Changing Our Approach to Drug Discovery.
Assay Drug Dev Technol
; 17(1): 3-7, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30657703
16.
A high-content screen identifies novel compounds that inhibit stress-induced TDP-43 cellular aggregation and associated cytotoxicity.
J Biomol Screen
; 19(1): 44-56, 2014 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-24019256
17.
A new means to identify type 3 secreted effectors: functionally interchangeable class IB chaperones recognize a conserved sequence.
mBio
; 3(1)2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22334517
18.
Angiogenic factors stimulate growth of adult neural stem cells.
PLoS One
; 5(2): e9414, 2010 Feb 26.
Artigo
Inglês
| MEDLINE | ID: mdl-20195471