Detalhe da pesquisa
1.
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity.
Cell
; 184(15): 4032-4047.e31, 2021 07 22.
Artigo
Inglês
| MEDLINE | ID: mdl-34171309
2.
GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies.
Mol Cell
; 84(10): 1886-1903.e10, 2024 May 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38688280
3.
Integrative clinical genomics of advanced prostate cancer.
Cell
; 161(5): 1215-1228, 2015 May 21.
Artigo
Inglês
| MEDLINE | ID: mdl-26000489
4.
Braveheart, a long noncoding RNA required for cardiovascular lineage commitment.
Cell
; 152(3): 570-83, 2013 Jan 31.
Artigo
Inglês
| MEDLINE | ID: mdl-23352431
5.
Recurrent SRSF2 mutations in MDS affect both splicing and NMD.
Genes Dev
; 34(5-6): 413-427, 2020 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32001512
6.
Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing.
Mol Cell
; 72(3): 496-509.e9, 2018 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30388411
7.
Most human introns are recognized via multiple and tissue-specific branchpoints.
Genes Dev
; 32(7-8): 577-591, 2018 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29666160
8.
Integrative Clinical Genomics of Advanced Prostate Cancer.
Cell
; 162(2): 454, 2015 Jul 16.
Artigo
Inglês
| MEDLINE | ID: mdl-28843286
9.
Spliceosomal disruption of the non-canonical BAF complex in cancer.
Nature
; 574(7778): 432-436, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31597964
10.
Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis.
Nature
; 574(7777): 273-277, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31578525
11.
The RNA Surveillance Factor UPF1 Represses Myogenesis via Its E3 Ubiquitin Ligase Activity.
Mol Cell
; 67(2): 239-251.e6, 2017 Jul 20.
Artigo
Inglês
| MEDLINE | ID: mdl-28669802
12.
Congenital myotonic dystrophy-an RNA-mediated disease across a developmental continuum.
Genes Dev
; 31(11): 1067-1068, 2017 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28717044
13.
Coordinated missplicing of TMEM14C and ABCB7 causes ring sideroblast formation in SF3B1-mutant myelodysplastic syndrome.
Blood
; 139(13): 2038-2049, 2022 03 31.
Artigo
Inglês
| MEDLINE | ID: mdl-34861039
14.
Characterization of neoantigen-specific T cells in cancer resistant to immune checkpoint therapies.
Proc Natl Acad Sci U S A
; 118(30)2021 07 27.
Artigo
Inglês
| MEDLINE | ID: mdl-34285073
15.
Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis.
Genes Dev
; 30(9): 989-1001, 2016 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27151974
16.
RNA components of the spliceosome regulate tissue- and cancer-specific alternative splicing.
Genome Res
; 29(10): 1591-1604, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31434678
17.
Rare and private spliceosomal gene mutations drive partial, complete, and dual phenocopies of hotspot alterations.
Blood
; 135(13): 1032-1043, 2020 03 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31961934
18.
Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms.
Blood
; 136(13): 1477-1486, 2020 09 24.
Artigo
Inglês
| MEDLINE | ID: mdl-32640014
19.
Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1.
Proc Natl Acad Sci U S A
; 115(44): E10437-E10446, 2018 10 30.
Artigo
Inglês
| MEDLINE | ID: mdl-30322915
20.
Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A.
Genes Dev
; 27(9): 1032-45, 2013 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23651857