Detalhe da pesquisa
1.
Halo-1,2,3-triazoles: Valuable Compounds to Access Biologically Relevant Molecules.
Chembiochem
; 25(10): e202400150, 2024 May 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38554039
2.
Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase.
Nucleic Acids Res
; 50(10): 5793-5806, 2022 06 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35580049
3.
Synthesis of Bisubstrate Analogues for RNA Methylation Studies using two Transition-Metal-Catalyzed Reactions.
Chemistry
; 29(44): e202301134, 2023 Aug 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37222167
4.
Modulation of the Specificity of Carbapenems and Diazabicyclooctanes for Selective Activity against Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 66(9): e0235721, 2022 09 20.
Artigo
Inglês
| MEDLINE | ID: mdl-35943263
5.
Synthesis of Carbapenems Containing Peptidoglycan Mimetics and Inhibition of the Cross-Linking Activity of a Transpeptidase of l,d Specificity.
Chemistry
; 27(10): 3542-3551, 2021 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33336443
6.
Click and Release Chemistry for Activity-Based Purification of ß-Lactam Targets.
Chemistry
; 27(28): 7687-7695, 2021 May 17.
Artigo
Inglês
| MEDLINE | ID: mdl-33792096
7.
Synthesis of Triazole-Linked SAM-Adenosine Conjugates: Functionalization of Adenosine at N-1 or N-6 Position without Protecting Groups.
Molecules
; 25(14)2020 Jul 16.
Artigo
Inglês
| MEDLINE | ID: mdl-32708658
8.
Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites.
RNA Biol
; 16(6): 798-808, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30879411
9.
Critical Impact of Peptidoglycan Precursor Amidation on the Activity of l,d-Transpeptidases from Enterococcus faecium and Mycobacterium tuberculosis.
Chemistry
; 24(22): 5743-5747, 2018 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-29389045
10.
Synthesis of tRNA analogues containing a terminal ribose locked in the South conformation to study tRNA-dependent enzymes.
Org Biomol Chem
; 16(11): 1903-1911, 2018 03 14.
Artigo
Inglês
| MEDLINE | ID: mdl-29484333
11.
Insights into the interaction of high potency inhibitor IRC-083864 with phosphatase CDC25.
Proteins
; 85(4): 593-601, 2017 04.
Artigo
Inglês
| MEDLINE | ID: mdl-28056492
12.
Electrophilic RNA for Peptidyl-RNA Synthesis and Site-Specific Cross-Linking with tRNA-Binding Enzymes.
Angew Chem Int Ed Engl
; 55(43): 13553-13557, 2016 10 17.
Artigo
Inglês
| MEDLINE | ID: mdl-27667506
13.
Synthesis of 3'-fluoro-tRNA analogues for exploring non-ribosomal peptide synthesis in bacteria.
Chembiochem
; 16(3): 477-86, 2015 Feb 09.
Artigo
Inglês
| MEDLINE | ID: mdl-25586254
14.
Synthesis of 3'-triazoyl-dinucleotides as precursors of stable Phe-tRNA(Phe) and Leu-tRNA(Leu) analogues.
Bioorg Med Chem Lett
; 24(15): 3231-3, 2014 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24986659
15.
The catalytic mechanism of the RNA methyltransferase METTL3.
Elife
; 122024 Mar 12.
Artigo
Inglês
| MEDLINE | ID: mdl-38470714
16.
Synthesis and biological evaluation of non-isomerizable analogues of Ala-tRNA(Ala).
Org Biomol Chem
; 11(36): 6161-9, 2013 Sep 28.
Artigo
Inglês
| MEDLINE | ID: mdl-23925523
17.
The catalytic mechanism of the RNA methyltransferase METTL3.
bioRxiv
; 2023 Dec 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37732228
18.
Design and synthesis of novel bis-thiazolone derivatives as micromolar CDC25 phosphatase inhibitors: effect of dimerisation on phosphatase inhibition.
Bioorg Med Chem Lett
; 22(24): 7345-50, 2012 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23141909
19.
Study of the docking-dependent PLK1 phosphorylation of the CDC25B phosphatase.
Biochem Biophys Res Commun
; 410(1): 87-90, 2011 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-21640712
20.
Novel naphthoquinone and quinolinedione inhibitors of CDC25 phosphatase activity with antiproliferative properties.
Bioorg Med Chem
; 16(19): 9040-9, 2008 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18789703