Detalhe da pesquisa
1.
Splicing repression is a major function of TDP-43 in motor neurons.
Acta Neuropathol
; 138(5): 813-826, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31332509
2.
Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations.
Proc Natl Acad Sci U S A
; 113(47): E7580-E7589, 2016 11 22.
Artigo
Inglês
| MEDLINE | ID: mdl-27834214
3.
A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS-FTD.
Nat Med
; 30(2): 382-393, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38278991
4.
Expression of constitutively active FoxO3 in murine forebrain leads to a loss of neural progenitors.
FASEB J
; 26(12): 4990-5001, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-22935140
5.
The dynactin p150 subunit: cell biology studies of sequence changes found in ALS/MND and Parkinsonian syndromes.
J Neural Transm (Vienna)
; 120(5): 785-98, 2013 May.
Artigo
Inglês
| MEDLINE | ID: mdl-23143281
6.
A fluid biomarker reveals loss of TDP-43 splicing repression in pre-symptomatic ALS.
bioRxiv
; 2023 Jan 24.
Artigo
Inglês
| MEDLINE | ID: mdl-36789434
7.
A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons.
Hum Mol Genet
; 19(22): 4385-98, 2010 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20807776
8.
Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis.
Sci Transl Med
; 14(628): eabi9196, 2022 01 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35044790
9.
Neuroprotective function of cellular prion protein in a mouse model of amyotrophic lateral sclerosis.
Am J Pathol
; 176(3): 1409-20, 2010 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-20075202
10.
Author Correction: A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS-FTD.
Nat Med
; 30(5): 1504, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38580817
11.
Tdp-43 cryptic exons are highly variable between cell types.
Mol Neurodegener
; 12(1): 13, 2017 02 02.
Artigo
Inglês
| MEDLINE | ID: mdl-28153034
12.
The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model.
Nat Commun
; 7: 12082, 2016 07 04.
Artigo
Inglês
| MEDLINE | ID: mdl-27373369
13.
Intraventricular Delivery of siRNA Nanoparticles to the Central Nervous System.
Mol Ther Nucleic Acids
; 4: e242, 2015 May 12.
Artigo
Inglês
| MEDLINE | ID: mdl-25965552
14.
Mice with a mutation in the dynein heavy chain 1 gene display sensory neuropathy but lack motor neuron disease.
Exp Neurol
; 215(1): 146-52, 2009 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-18952079
15.
Vacuolization correlates with spin-spin relaxation time in motor brainstem nuclei and behavioural tests in the transgenic G93A-SOD1 mouse model of ALS.
Eur J Neurosci
; 26(7): 1895-901, 2007 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-17868365