Detalhe da pesquisa
1.
GPCR-G Protein-ß-Arrestin Super-Complex Mediates Sustained G Protein Signaling.
Cell
; 166(4): 907-919, 2016 Aug 11.
Artigo
Inglês
| MEDLINE | ID: mdl-27499021
2.
BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated Gq activation at early endosomes.
Proc Natl Acad Sci U S A
; 118(20)2021 05 18.
Artigo
Inglês
| MEDLINE | ID: mdl-33990469
3.
Michaelis-Menten Quantification of Ligand Signaling Bias Applied to the Promiscuous Vasopressin V2 Receptor.
Mol Pharmacol
; 102(3): 139-149, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35779859
4.
Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor.
Nat Chem Biol
; 15(1): 11-17, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30510194
5.
Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor.
Nat Chem Biol
; 15(2): 206, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30573766
6.
GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets.
Mol Pharmacol
; 93(6): 581-591, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29572336
7.
Quantification of ligand bias for clinically relevant ß2-adrenergic receptor ligands: implications for drug taxonomy.
Mol Pharmacol
; 85(3): 492-509, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24366668
8.
EGFR signaling and pharmacology in oncology revealed with innovative BRET-based biosensors.
Commun Biol
; 7(1): 250, 2024 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38429428
9.
Lateral allosterism in the glucagon receptor family: glucagon-like peptide 1 induces G-protein-coupled receptor heteromer formation.
Mol Pharmacol
; 81(3): 309-18, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22108912
10.
Multimerization of Staufen1 in live cells.
RNA
; 16(3): 585-97, 2010 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-20075165
11.
A systematic analysis of prostaglandin E2 type 3 receptor isoform signaling reveals isoform- and species-dependent L798106 Gαz-biased agonist responses.
Eur J Pharmacol
; 927: 175043, 2022 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35598847
12.
Effector membrane translocation biosensors reveal G protein and ßarrestin coupling profiles of 100 therapeutically relevant GPCRs.
Elife
; 112022 03 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35302493
13.
Receptor-regulated interaction of activator of G-protein signaling-4 and Galphai.
J Biol Chem
; 285(27): 20588-94, 2010 Jul 02.
Artigo
Inglês
| MEDLINE | ID: mdl-20452976
14.
Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor.
J Biol Chem
; 285(44): 33949-58, 2010 Oct 29.
Artigo
Inglês
| MEDLINE | ID: mdl-20716524
15.
Combining resonance energy transfer methods reveals a complex between the alpha2A-adrenergic receptor, Galphai1beta1gamma2, and GRK2.
FASEB J
; 24(12): 4733-43, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-20696855
16.
Mechanistic insights into dopaminergic and serotonergic neurotransmission - concerted interactions with helices 5 and 6 drive the functional outcome.
Chem Sci
; 12(33): 10990-11003, 2021 Aug 25.
Artigo
Inglês
| MEDLINE | ID: mdl-34522296
17.
Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling.
Cell Rep
; 35(11): 109246, 2021 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34133934
18.
Multiplexing of multicolor bioluminescence resonance energy transfer.
Biophys J
; 99(12): 4037-46, 2010 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21156147
19.
Vasopressin type 2 receptor V88M mutation: molecular basis of partial and complete nephrogenic diabetes insipidus.
Nephron Physiol
; 114(1): p1-10, 2010.
Artigo
Inglês
| MEDLINE | ID: mdl-19816050
20.
Signal profiling of the ß1AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by ß1AR and ß2AR.
Sci Rep
; 10(1): 8779, 2020 05 29.
Artigo
Inglês
| MEDLINE | ID: mdl-32471984