Detalhe da pesquisa
1.
X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis.
Nature
; 521(7550): 105-9, 2015 May 07.
Artigo
Inglês
| MEDLINE | ID: mdl-25686610
2.
Chlorinated Glycopeptide Antibiotic Peptide Precursors Improve Cytochrome P450-Catalyzed Cyclization Cascade Efficiency.
Biochemistry
; 56(9): 1239-1247, 2017 03 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28218515
3.
3'-NADP and 3'-NAADP, Two Metabolites Formed by the Bacterial Type III Effector AvrRxo1.
J Biol Chem
; 291(44): 22868-22880, 2016 10 28.
Artigo
Inglês
| MEDLINE | ID: mdl-27621317
4.
Regulation of the P450 Oxygenation Cascade Involved in Glycopeptide Antibiotic Biosynthesis.
J Am Chem Soc
; 138(21): 6746-53, 2016 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27213615
5.
Biochemical and structural characterisation of the second oxidative crosslinking step during the biosynthesis of the glycopeptide antibiotic A47934.
Beilstein J Org Chem
; 12: 2849-2864, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-28144358
6.
Structural aspects of phenylglycines, their biosynthesis and occurrence in peptide natural products.
Nat Prod Rep
; 32(8): 1207-35, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-25940955
7.
Azobenzene C-Nucleosides for Photocontrolled Hybridization of DNA at Room Temperature.
Chemistry
; 21(49): 17870-6, 2015 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26489532
8.
Reversible photoswitching of RNA hybridization at room temperature with an azobenzene C-nucleoside.
Chemistry
; 21(7): 2845-54, 2015 Feb 09.
Artigo
Inglês
| MEDLINE | ID: mdl-25537843
9.
Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics.
Org Biomol Chem
; 13(7): 2012-21, 2015 Feb 21.
Artigo
Inglês
| MEDLINE | ID: mdl-25501135
10.
Sequential In Vitro Cyclization by Cytochrome P450 Enzymes of Glycopeptide Antibiotic Precursors Bearing the X-Domain from Nonribosomal Peptide Biosynthesis.
Angew Chem Int Ed Engl
; 54(52): 15715-9, 2015 Dec 21.
Artigo
Inglês
| MEDLINE | ID: mdl-26549530
11.
Cytochrome P450 OxyBtei catalyzes the first phenolic coupling step in teicoplanin biosynthesis.
Chembiochem
; 15(18): 2719-28, 2014 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25358800
12.
The structure of a transient complex of a nonribosomal peptide synthetase and a cytochrome P450 monooxygenase.
Angew Chem Int Ed Engl
; 53(32): 8518-22, 2014 Aug 04.
Artigo
Inglês
| MEDLINE | ID: mdl-25044735
13.
Spiropyran photoswitches in the context of DNA: synthesis and photochromic properties.
Chemistry
; 19(46): 15726-34, 2013 Nov 11.
Artigo
Inglês
| MEDLINE | ID: mdl-24115210
14.
Light-controlled tools.
Angew Chem Int Ed Engl
; 51(34): 8446-76, 2012 Aug 20.
Artigo
Inglês
| MEDLINE | ID: mdl-22829531
15.
Systematic risk identification and assessment using a new risk map in pharmaceutical R&D.
Drug Discov Today
; 26(12): 2786-2793, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34229082
16.
Efficient cosubstrate enzyme pairs for sequence-specific methyltransferase-directed photolabile caging of DNA.
Chem Commun (Camb)
; 54(90): 12718-12721, 2018 Nov 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30357150
17.
The Thioesterase Domain in Glycopeptide Antibiotic Biosynthesis Is Selective for Cross-Linked Aglycones.
ACS Chem Biol
; 13(1): 110-120, 2018 01 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29192758
18.
Investigating Cytochrome P450 specificity during glycopeptide antibiotic biosynthesis through a homologue hybridization approach.
J Inorg Biochem
; 185: 43-51, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29751197
19.
A route to diastereomerically pure phenylglycine thioester peptides: crucial intermediates for investigating glycopeptide antibiotic biosynthesis.
Chem Commun (Camb)
; 54(17): 2146-2149, 2018 Feb 22.
Artigo
Inglês
| MEDLINE | ID: mdl-29423498
20.
The ng_ζ1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis.
Nat Commun
; 9(1): 1686, 2018 04 27.
Artigo
Inglês
| MEDLINE | ID: mdl-29703974