Detalhe da pesquisa
1.
On the Possible Effect of Phytic Acid (Myo-Inositol Hexaphosphoric Acid, IP6) on Cytochromes P450 and Systems of Xenobiotic Metabolism in Different Hepatic Models.
Int J Mol Sci
; 25(7)2024 Mar 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38612422
2.
Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor.
Drug Metab Dispos
; 46(3): 223-236, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29269410
3.
In vitro infection of primary human hepatocytes by HCV-positive sera: insights on a highly relevant model.
Gut
; 63(9): 1490-500, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24153249
4.
The WNT/ß-catenin pathway is a transcriptional regulator of CYP2E1, CYP1A2, and aryl hydrocarbon receptor gene expression in primary human hepatocytes.
Mol Pharmacol
; 86(6): 624-34, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25228302
5.
Butyrate, a typical product of gut microbiome, affects function of the AhR gene, being a possible agent of crosstalk between gut microbiome, and hepatic drug metabolism.
J Nutr Biochem
; 107: 109042, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35533897
6.
Primary hepatocytes isolated from human and porcine donors display similar patterns of cytochrome p450 expression following exposure to prototypical activators of AhR, CAR and PXR.
Curr Res Toxicol
; 2: 149-158, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34345857
7.
Methods for simultaneous and quantitative isolation of mitochondrial DNA, nuclear DNA and RNA from mammalian cells.
Biotechniques
; 69(6): 436-442, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33103926
8.
Biocompatible modified water as a non-pharmaceutical approach to prevent metabolic syndrome features in obesogenic diet-fed mice.
Food Chem Toxicol
; 141: 111403, 2020 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-32387306
9.
Mesenchymal stem cells seeded on a human amniotic membrane improve liver regeneration and mouse survival after extended hepatectomy.
J Tissue Eng Regen Med
; 12(4): 1062-1073, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29106037
10.
Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV.
Nat Commun
; 7: 12203, 2016 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27417143
11.
Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of ß-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling.
Toxicol Sci
; 148(1): 261-75, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26259606
12.
Use of human hepatocytes to investigate HCV infection.
Methods Mol Biol
; 640: 447-62, 2010.
Artigo
Inglês
| MEDLINE | ID: mdl-20645067