Detalhe da pesquisa
1.
Precision proteoform design for 4R tau isoform selective templated aggregation.
Proc Natl Acad Sci U S A
; 121(15): e2320456121, 2024 Apr 09.
Artigo
Inglês
| MEDLINE | ID: mdl-38568974
2.
A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein.
J Biol Chem
; 300(4): 107163, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38484799
3.
Glial reactivity and T cell infiltration in frontotemporal lobar degeneration with tau pathology.
Brain
; 147(2): 590-606, 2024 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37703311
4.
NLRP3 inflammasome activation drives tau pathology.
Nature
; 575(7784): 669-673, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31748742
5.
Clinical value of plasma ALZpath pTau217 immunoassay for assessing mild cognitive impairment.
J Neurol Neurosurg Psychiatry
; 2024 Apr 24.
Artigo
Inglês
| MEDLINE | ID: mdl-38658136
6.
Novel avenues of tau research.
Alzheimers Dement
; 20(3): 2240-2261, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38170841
7.
Calpain-2 Mediates MBNL2 Degradation and a Developmental RNA Processing Program in Neurodegeneration.
J Neurosci
; 42(25): 5102-5114, 2022 06 22.
Artigo
Inglês
| MEDLINE | ID: mdl-35606145
8.
Clustering of Tau fibrils impairs the synaptic composition of α3-Na+/K+-ATPase and AMPA receptors.
EMBO J
; 38(3)2019 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30630857
9.
Extracellular vesicles: Major actors of heterogeneity in tau spreading among human tauopathies.
Mol Ther
; 30(2): 782-797, 2022 02 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34563677
10.
Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment.
Mol Ther
; 30(4): 1484-1499, 2022 04 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35007758
11.
Can the administration of platelet lysates to the brain help treat neurological disorders?
Cell Mol Life Sci
; 79(7): 379, 2022 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-35750991
12.
A Polyaminobiaryl-Based ß-secretase Modulator Alleviates Cognitive Impairments, Amyloid Load, Astrogliosis, and Neuroinflammation in APPSwe/PSEN1ΔE9 Mice Model of Amyloid Pathology.
Int J Mol Sci
; 24(6)2023 Mar 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36982363
13.
Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response.
J Neuroinflammation
; 19(1): 307, 2022 Dec 20.
Artigo
Inglês
| MEDLINE | ID: mdl-36539803
14.
Efficacy of lanreotide 120 mg primary therapy on tumour shrinkage and ophthalmologic symptoms in acromegaly after 1 month.
Clin Endocrinol (Oxf)
; 97(1): 52-63, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35470446
15.
Functional Analyses of Two Novel LRRK2 Pathogenic Variants in Familial Parkinson's Disease.
Mov Disord
; 37(8): 1761-1767, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35708213
16.
Human platelet lysate biotherapy for traumatic brain injury: preclinical assessment.
Brain
; 144(10): 3142-3158, 2021 11 29.
Artigo
Inglês
| MEDLINE | ID: mdl-34086871
17.
Current directions in tau research: Highlights from Tau 2020.
Alzheimers Dement
; 18(5): 988-1007, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34581500
18.
Plasma amyloid beta predicts conversion to dementia in subjects with mild cognitive impairment: The BALTAZAR study.
Alzheimers Dement
; 18(12): 2537-2550, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35187794
19.
Discovery of Compounds That Selectively Repress the Amyloidogenic Processing of the Amyloid Precursor Protein: Design, Synthesis and Pharmacological Evaluation of Diphenylpyrazoles.
Int J Mol Sci
; 23(21)2022 Oct 28.
Artigo
Inglês
| MEDLINE | ID: mdl-36361896
20.
Microtube Array Membrane Encapsulated Cell Therapy: A Novel Platform Technology Solution for Treatment of Alzheimer's Disease.
Int J Mol Sci
; 23(12)2022 Jun 20.
Artigo
Inglês
| MEDLINE | ID: mdl-35743295