Detalhe da pesquisa
1.
Over-expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease.
J Neurochem
; 124(6): 880-93, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23121022
2.
mTOR drives cerebrovascular, synaptic, and cognitive dysfunction in normative aging.
Aging Cell
; 19(1): e13057, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31693798
3.
Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's disease.
J Cereb Blood Flow Metab
; 33(9): 1412-21, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23801246
4.
Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice.
J Cereb Blood Flow Metab
; 33(10): 1605-11, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23838831