Detalhe da pesquisa
1.
A Bayesian approach to Mendelian randomization using summary statistics in the univariable and multivariable settings with correlated pleiotropy.
Am J Hum Genet
; 111(1): 165-180, 2024 Jan 04.
Artigo
Inglês
| MEDLINE | ID: mdl-38181732
2.
Multi-response Mendelian randomization: Identification of shared and distinct exposures for multimorbidity and multiple related disease outcomes.
Am J Hum Genet
; 110(7): 1177-1199, 2023 07 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37419091
3.
Using genetic association data to guide drug discovery and development: Review of methods and applications.
Am J Hum Genet
; 110(2): 195-214, 2023 02 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36736292
4.
Relaxing parametric assumptions for non-linear Mendelian randomization using a doubly-ranked stratification method.
PLoS Genet
; 19(6): e1010823, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-37390109
5.
Uncovering associations between pre-existing conditions and COVID-19 Severity: A polygenic risk score approach across three large biobanks.
PLoS Genet
; 19(12): e1010907, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-38113267
6.
Robust use of phenotypic heterogeneity at drug target genes for mechanistic insights: Application of cis-multivariable Mendelian randomization to GLP1R gene region.
Genet Epidemiol
; 48(4): 151-163, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38379245
7.
Combining evidence from Mendelian randomization and colocalization: Review and comparison of approaches.
Am J Hum Genet
; 109(5): 767-782, 2022 05 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35452592
8.
Noise-augmented directional clustering of genetic association data identifies distinct mechanisms underlying obesity.
PLoS Genet
; 18(1): e1009975, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35085229
9.
Birth weight influences cardiac structure, function, and disease risk: evidence of a causal association.
Eur Heart J
; 45(6): 443-454, 2024 Feb 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37738114
10.
Statistical methods for cis-Mendelian randomization with two-sample summary-level data.
Genet Epidemiol
; 47(1): 3-25, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36273411
11.
LDL-c Lowering, Ischemic Stroke, and Small Vessel Disease Brain Imaging Biomarkers: A Mendelian Randomization Study.
Stroke
; 2024 Apr 04.
Artigo
Inglês
| MEDLINE | ID: mdl-38572634
12.
Risk Factors for Intracerebral Hemorrhage: Genome-Wide Association Study and Mendelian Randomization Analyses.
Stroke
; 2024 May 08.
Artigo
Inglês
| MEDLINE | ID: mdl-38716647
13.
Genetic investigation into the broad health implications of caffeine: evidence from phenome-wide, proteome-wide and metabolome-wide Mendelian randomization.
BMC Med
; 22(1): 81, 2024 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38378567
14.
Genetically predicted plasma cortisol and common chronic diseases: A Mendelian randomization study.
Clin Endocrinol (Oxf)
; 100(3): 238-244, 2024 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37667866
15.
Impaired glucose tolerance and cardiovascular risk factors in relation to infertility: a Mendelian randomization analysis in the Norwegian Mother, Father, and Child Cohort Study.
Hum Reprod
; 39(2): 436-441, 2024 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37949105
16.
Arterial Stiffness and Diabetes Risk in Framingham Heart Study and UK Biobank.
Circ Res
; 131(6): 545-554, 2022 09 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35946401
17.
Relationship Between Ascending Thoracic Aortic Diameter and Blood Pressure: A Mendelian Randomization Study.
Arterioscler Thromb Vasc Biol
; 43(2): 359-366, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36601961
18.
A data-adaptive method for investigating effect heterogeneity with high-dimensional covariates in Mendelian randomization.
BMC Med Res Methodol
; 24(1): 34, 2024 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-38341532
19.
Educational attainment, structural brain reserve and Alzheimer's disease: a Mendelian randomization analysis.
Brain
; 146(5): 2059-2074, 2023 05 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36310536
20.
Genomic atlas of the human plasma proteome.
Nature
; 558(7708): 73-79, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29875488