Detalhe da pesquisa
1.
Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.
Cell
; 175(4): 1045-1058.e16, 2018 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30388443
2.
A lower X-gate in TASK channels traps inhibitors within the vestibule.
Nature
; 582(7812): 443-447, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32499642
3.
Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.
EMBO J
; 40(14): e107294, 2021 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34031912
4.
Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Cell
; 136(2): 352-63, 2009 Jan 23.
Artigo
Inglês
| MEDLINE | ID: mdl-19167335
5.
Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair.
Genes Dev
; 25(17): 1859-70, 2011 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21896658
6.
Structural analysis of human KDM5B guides histone demethylase inhibitor development.
Nat Chem Biol
; 12(7): 539-45, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27214403
7.
Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis.
Ann Rheum Dis
; 75(6): 1255-61, 2016 06.
Artigo
Inglês
| MEDLINE | ID: mdl-26209657
8.
Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states.
Proc Natl Acad Sci U S A
; 110(24): 9710-5, 2013 Jun 11.
Artigo
Inglês
| MEDLINE | ID: mdl-23716676
9.
Structural insights into functional overlapping and differentiation among myosin V motors.
J Biol Chem
; 288(47): 34131-34145, 2013 Nov 22.
Artigo
Inglês
| MEDLINE | ID: mdl-24097982
10.
A scintillation proximity assay for histone demethylases.
Anal Biochem
; 463: 54-60, 2014 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25010373
11.
Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate.
J Med Chem
; 67(6): 4525-4540, 2024 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38294854
12.
Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist.
Structure
; 2024 May 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38815576
13.
Protein binder toolbox for studies of solute carrier transporters.
J Mol Biol
; : 168665, 2024 Jun 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38878854
14.
A prominent ß-hairpin structure in the winged-helix domain of RECQ1 is required for DNA unwinding and oligomer formation.
Nucleic Acids Res
; 39(5): 1703-17, 2011 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-21059676
15.
Structural characterization of human urea transporters UT-A and UT-B and their inhibition.
Sci Adv
; 9(39): eadg8229, 2023 09 29.
Artigo
Inglês
| MEDLINE | ID: mdl-37774028
16.
High-Throughput Expression and Purification of Human Solute Carriers for Structural and Biochemical Studies.
J Vis Exp
; (199)2023 09 29.
Artigo
Inglês
| MEDLINE | ID: mdl-37843272
17.
Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.
iScience
; 26(2): 105928, 2023 Feb 17.
Artigo
Inglês
| MEDLINE | ID: mdl-36619367
18.
Structure of the human RECQ1 helicase reveals a putative strand-separation pin.
Proc Natl Acad Sci U S A
; 106(4): 1039-44, 2009 Jan 27.
Artigo
Inglês
| MEDLINE | ID: mdl-19151156
19.
FAS2FURIOUS: Moderate-Throughput Secreted Expression of Difficult Recombinant Proteins in Drosophila S2 Cells.
Front Bioeng Biotechnol
; 10: 871933, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35600892
20.
Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain.
Nat Commun
; 13(1): 4087, 2022 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35840580