Effect of attention on frontal distribution of delta activity and cerebral metabolic rate in schizophrenia.

15 patients with schizophrenia and nine normal volunteers had 32 channel topographic EEG recorded for spectral analysis during the uptake of 18-F-deoxyglucose (FDG) for positron emission tomography (PET). Both patients and controls performed the Continuous Performance Test, a visual vigilance task, during FDG uptake. EEG was also obtained during an initial pre-FDG resting period. Each EEG epoch was individually inspected for eye movement artifacts. Analysis confirmed increased delta activity in the frontal region of patients with schizophrenia in comparison to normal controls, and a significant correlation between increased frontal delta and relative reduction in frontal lobe metabolism among patients with schizophrenia. This finding of increased delta is consistent with PET, blood flow and topographic EEG studies of schizophrenia, suggesting reduced frontal activity.

Influence of crambe meal as a protein source on intake, site of digestion, ruminal fermentation, and microbial efficiency in beef steers fed grass hay.

Four ruminally and duodenally cannulated beef steers (558 +/- 37 kg) were arranged in a 4 x 4 Latin square to evaluate the influence of crambe meal as a protein source on intake, digestion, and microbial efficiency. Steers were offered chopped (10.2 cm) brome hay (6.2% CP) for ad libitum consumption and one of four supplements. Protein sources used were soybean and crambe meals (CM). Protein sources were blended to provide four levels of supplemental CM protein (0, 33, 67, and 100%). Protein supplements were fed to provide similar amounts of protein and energy. Amounts of supplements fed were 831, 885, 950, and 996 g of DM/steer daily for 0, 33, 67, and 100% CM treatments, respectively. Crambe meal represented 0, 2.00, 3.83, and 5.88% of the DM intake for respective treatments. Steers were allowed a 21-d adaptation to diets before each collection period. Supplements were offered at 0800 and forage at 0830. Crambe meal had no influence (P > .10) on forage and total DM intake (grams/kilogram of BW). Apparent total tract, ruminal, and postruminal digestion of OM, NDF, ADF, and N were unaffected (P > .10) by CM supplementation.(ABSTRACT TRUNCATED AT 250 WORDS)

Rapid quantitative procedure for removing cholesterol from butter fat.

Cholesterol is rapidly and quantitatively removed from butter fat by passage of the fat in hexane or benzene solution over a column of Celite impregnated with an aqueous solution of digitonin.

Focal left temporal slow EEG activity is related to a verbal recent memory deficit in a non-demented elderly population.

Neuropsychological measures of memory and cognition and topographical quantitative EEG were obtained on 35 healthy, non-demented, right-handed, elderly subjects aged 60-81. All were free of medications which impair cognition. They were divided into a left temporal slow abnormality group (n = 9) and a control group (n = 26) on the basis of topographically normalized measures of both delta and theta activity for the left temporal lead T3. The group with left temporal slow activity was significantly deficient on measures of memory savings and memory losses derived from the Logical Memory (Story Recall) Test in the Wechsler Memory Scale--Revised. There were no significant differences between these two groups on the non-memory cognitive tasks. This predominant verbal recent memory deficit profile is reasonably similar to the neuropsychological deficit profile of very mildly demented Alzheimer patients. Because left temporal slow EEG activity is also the predominant EEG abnormality in mild Alzheimer patients, a prospective study should be done to determine if this abnormality in non-demented elderly subjects is most often a preclinical sign of Alzheimer's disease.