Detalhe da pesquisa
1.
Structure-activity relationship study of central pyridine-derived TYK2 JH2 inhibitors: Optimization of the PK profile through C4' and C6 variations.
Bioorg Med Chem Lett
; 91: 129373, 2023 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37315697
2.
Measurement Properties of the CAPACITY Instrument to Assess Perceived Communication With the Health Care Team Among Care Partners of Patients With Cognitive Impairment.
Med Care
; 58(9): 842-849, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32826749
3.
Racially diverse participant registries to facilitate the recruitment of African Americans into presymptomatic Alzheimer's disease studies.
Alzheimers Dement
; 16(8): 1107-1114, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32543781
4.
Determination of Real Time in Vivo Drug Receptor Occupancy for a Covalent Binding Drug as a Clinical Pharmacodynamic Biomarker by Immunocapture-LC-MS/MS.
Anal Chem
; 91(13): 8443-8452, 2019 07 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31247719
5.
Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop.
Mol Cell
; 43(1): 57-71, 2011 Jul 08.
Artigo
Inglês
| MEDLINE | ID: mdl-21726810
6.
Conversion of carbazole carboxamide based reversible inhibitors of Bruton's tyrosine kinase (BTK) into potent, selective irreversible inhibitors in the carbazole, tetrahydrocarbazole, and a new 2,3-dimethylindole series.
Bioorg Med Chem Lett
; 28(18): 3080-3084, 2018 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30097367
7.
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer.
Genes Dev
; 24(8): 837-52, 2010 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20395368
8.
Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain.
J Biol Chem
; 290(17): 11061-74, 2015 Apr 24.
Artigo
Inglês
| MEDLINE | ID: mdl-25762719
9.
Design and synthesis of carbazole carboxamides as promising inhibitors of Bruton's tyrosine kinase (BTK) and Janus kinase 2 (JAK2).
Bioorg Med Chem Lett
; 25(19): 4265-9, 2015 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26320619
10.
Pre-clinical cognitive phenotypes for Alzheimer disease: a latent profile approach.
Am J Geriatr Psychiatry
; 22(11): 1364-74, 2014 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-24080384
11.
Purine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors for autoimmune diseases.
Bioorg Med Chem Lett
; 24(9): 2206-11, 2014 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24685542
12.
Impact of ¹8F-florbetapir PET imaging of ß-amyloid neuritic plaque density on clinical decision-making.
Neurocase
; 20(4): 466-73, 2014 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-23672654
13.
The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes.
Alzheimers Dement
; 10(5): 541-51, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24439168
14.
Association between results of an amyloid PET scan and healthcare utilization in individuals with cognitive impairment.
J Am Geriatr Soc
; 72(3): 707-717, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38069618
15.
Beta amyloid PET scans for dementia diagnoses: Practice and research implications from CARE-IDEAS.
J Am Geriatr Soc
; 2024 May 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38798126
16.
Elevated Amyloid-ß PET Scan and Cognitive and Functional Decline in Mild Cognitive Impairment and Dementia of Uncertain Etiology.
J Alzheimers Dis
; 97(3): 1161-1171, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38306055
17.
Neuropsychological predictors of dementia in late-life major depressive disorder.
Am J Geriatr Psychiatry
; 21(3): 297-306, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23395197
18.
Phenotypic regional functional imaging patterns during memory encoding in mild cognitive impairment and Alzheimer's disease.
Alzheimers Dement
; 9(3): 284-94, 2013 May.
Artigo
Inglês
| MEDLINE | ID: mdl-22841497
19.
Prevalence and incidence of depressive symptoms and diagnosis of depression as associated with elevated amyloid among Medicare beneficiaries with cognitive impairment.
J Affect Disord
; 334: 293-296, 2023 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37150216
20.
Incidence of dementia and cognitive impairment, not dementia in the United States.
Ann Neurol
; 70(3): 418-26, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21425187