Detalhe da pesquisa
1.
SETD7 functions as a transcription repressor in prostate cancer via methylating FOXA1.
Proc Natl Acad Sci U S A
; 120(33): e2220472120, 2023 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37549269
2.
Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress.
Proc Natl Acad Sci U S A
; 119(3)2022 01 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35031563
3.
Exploiting the tumor-suppressive activity of the androgen receptor by CDK4/6 inhibition in castration-resistant prostate cancer.
Mol Ther
; 30(4): 1628-1644, 2022 04 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35121110
4.
Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer.
Nucleic Acids Res
; 45(7): 3738-3751, 2017 04 20.
Artigo
Inglês
| MEDLINE | ID: mdl-28062857
5.
Androgen receptor splice variants drive castration-resistant prostate cancer metastasis by activating distinct transcriptional programs.
J Clin Invest
; 2024 Apr 30.
Artigo
Inglês
| MEDLINE | ID: mdl-38687617
6.
Androgen receptor serine 81 phosphorylation mediates chromatin binding and transcriptional activation.
J Biol Chem
; 287(11): 8571-83, 2012 Mar 09.
Artigo
Inglês
| MEDLINE | ID: mdl-22275373
7.
Androgen Receptor Enhances p27 Degradation in Prostate Cancer Cells through Rapid and Selective TORC2 Activation.
J Biol Chem
; 287(3): 2090-8, 2012 Jan 13.
Artigo
Inglês
| MEDLINE | ID: mdl-22139837
8.
LSD1 Inhibition Disrupts Super-Enhancer-Driven Oncogenic Transcriptional Programs in Castration-Resistant Prostate Cancer.
Cancer Res
; 83(10): 1684-1698, 2023 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36877164
9.
Demethylation of EHMT1/GLP Protein Reprograms Its Transcriptional Activity and Promotes Prostate Cancer Progression.
Cancer Res Commun
; 3(8): 1716-1730, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37663929
10.
Increased AR expression in castration-resistant prostate cancer rapidly induces AR signaling reprogramming with the collaboration of EZH2.
Front Oncol
; 12: 1021845, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36408179
11.
RB1 loss in castration-resistant prostate cancer confers vulnerability to LSD1 inhibition.
Oncogene
; 41(6): 852-864, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34975152
12.
Pioneer of prostate cancer: past, present and the future of FOXA1.
Protein Cell
; 12(1): 29-38, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32946061
13.
Susceptibility-Associated Genetic Variation in NEDD9 Contributes to Prostate Cancer Initiation and Progression.
Cancer Res
; 81(14): 3766-3776, 2021 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33632899
14.
A Novel Mechanism to Induce BRCAness in Cancer Cells.
Cancer Res
; 80(14): 2977-2978, 2020 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32669350
15.
Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer.
Nat Genet
; 52(10): 1011-1017, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32868907
16.
LSD1 Activates PI3K/AKT Signaling Through Regulating p85 Expression in Prostate Cancer Cells.
Front Oncol
; 9: 721, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31428587
17.
TMPRSS2-ERG activates NO-cGMP signaling in prostate cancer cells.
Oncogene
; 38(22): 4397-4411, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30718921
18.
ZBTB7A Mediates the Transcriptional Repression Activity of the Androgen Receptor in Prostate Cancer.
Cancer Res
; 79(20): 5260-5271, 2019 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31444154
19.
c-Jun has multiple enhancing activities in the novel cross talk between the androgen receptor and Ets variant gene 1 in prostate cancer.
Mol Cancer Res
; 5(7): 725-35, 2007 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-17634427
20.
ETV1 is a novel androgen receptor-regulated gene that mediates prostate cancer cell invasion.
Mol Endocrinol
; 21(8): 1835-46, 2007 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-17505060