Detalhe da pesquisa
1.
OECD harmonised template 201: Structuring and reporting mechanistic information to foster the integration of new approach methodologies for hazard and risk assessment of chemicals.
Regul Toxicol Pharmacol
; 142: 105426, 2023 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-37277057
2.
Gauging innovation and health impact from biomedical research: survey results and interviews with recipients of EU-funding in the fields of Alzheimer's disease, breast cancer and prostate cancer.
Health Res Policy Syst
; 21(1): 66, 2023 Jun 29.
Artigo
Inglês
| MEDLINE | ID: mdl-37386455
3.
Temozolomide down-regulates P-glycoprotein in human blood-brain barrier cells by disrupting Wnt3 signaling.
Cell Mol Life Sci
; 71(3): 499-516, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23771630
4.
Insights in the chemical components of liposomes responsible for P-glycoprotein inhibition.
Nanomedicine
; 10(1): 77-87, 2014 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-23850894
5.
Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition.
Mol Cancer
; 12: 137, 2013 Nov 13.
Artigo
Inglês
| MEDLINE | ID: mdl-24225025
6.
Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance.
Mol Pharm
; 10(1): 161-74, 2013 Jan 07.
Artigo
Inglês
| MEDLINE | ID: mdl-23186264
7.
Digoxin and ouabain induce the efflux of cholesterol via liver X receptor signalling and the synthesis of ATP in cardiomyocytes.
Biochem J
; 447(2): 301-11, 2012 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22845468
8.
Probabilistic modelling of developmental neurotoxicity based on a simplified adverse outcome pathway network.
Comput Toxicol
; 21: 100206, 2022 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-35211661
9.
Towards a qAOP framework for predictive toxicology - Linking data to decisions.
Comput Toxicol
; 21: 100195, 2022 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-35211660
10.
Nitric oxide and P-glycoprotein modulate the phagocytosis of colon cancer cells.
J Cell Mol Med
; 15(7): 1492-504, 2011 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20716130
11.
Alzheimer's Disease, and Breast and Prostate Cancer Research: Translational Failures and the Importance to Monitor Outputs and Impact of Funded Research.
Animals (Basel)
; 10(7)2020 Jul 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32674379
12.
Digoxin and ouabain induce P-glycoprotein by activating calmodulin kinase II and hypoxia-inducible factor-1alpha in human colon cancer cells.
Toxicol Appl Pharmacol
; 240(3): 385-92, 2009 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19647009
13.
Classical inhibitors of NOX NAD(P)H oxidases are not specific.
Curr Drug Metab
; 9(8): 686-96, 2008 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-18855607
14.
Chemical alternatives assessment of different flame retardants - A case study including multi-walled carbon nanotubes as synergist.
Environ Int
; 101: 27-45, 2017 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-28161204
15.
Creating a Structured AOP Knowledgebase via Ontology-Based Annotations.
Appl In Vitro Toxicol
; 3(4): 298-311, 2017 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30057931
16.
An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells.
PLoS One
; 10(5): e0126159, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25955018
17.
Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma.
Oncotarget
; 6(2): 1128-42, 2015 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-25544757
18.
Carbonic anhydrase XII is a new therapeutic target to overcome chemoresistance in cancer cells.
Oncotarget
; 6(9): 6776-93, 2015 Mar 30.
Artigo
Inglês
| MEDLINE | ID: mdl-25686827
19.
Simvastatin and downstream inhibitors circumvent constitutive and stromal cell-induced resistance to doxorubicin in IGHV unmutated CLL cells.
Oncotarget
; 6(30): 29833-46, 2015 Oct 06.
Artigo
Inglês
| MEDLINE | ID: mdl-26284584
20.
Nanoparticle- and liposome-carried drugs: new strategies for active targeting and drug delivery across blood-brain barrier.
Curr Drug Metab
; 14(6): 625-40, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23869808